PALAZZO, LUCA
PALAZZO, LUCA
DIPARTIMENTO DI MEDICINA MOLECOLARE E BIOTECNOLOGIE MEDICHE
The PARG frontier: mechanisms of PAR turnover and opportunities in precision oncology
2026 Catara, Giuliana; Gerace, Gaetano; Lauro, Raffaella; Palazzo, Luca
Histidine and tyrosine residues are targets for SIRT6 ADP-ribosylation activity
2026 Gregor Matthias Rack, Johannes; Prokhorova, Evgeniia; Lauro, Raffaella; Georgina Kopasz, Anna; Baretić, Domagoj; Raggiaschi, Roberto; Mutabdzija, Jovana; V Filippov, Dmitri; Timinszky, Gyula; Leidecker, Orsolya; Ahel, Ivan; Palazzo, Luca
Expulsion of iron-rich ferritin via CD63-mediated exosome drives ferroptosis resistance in ovarian cancer cells
2025 Battaglia, A. M.; Sacco, A.; Giorgio, E.; Petriaggi, L.; Elzanowska, J.; Cruz, A. R.; Rocha, L.; Pereira, C. E.; Strano Moraes, M. C.; Palazzo, L.; De Vitis, C.; Costa-Silva, B.; Biamonte, F.
Suppression of ADP-ribosylation reversal triggers cell vulnerability to alkylating agents
2025 Caggiano, Rocco; Prokhorova, Evgeniia; Duma, Lena; Schützenhofer, Kira; Lauro, Raffaella; Catara, Giuliana; Melillo, Rosa Marina; Celetti, Angela; Smith, Rebecca; Weroha, S John; Kaufmann, Scott H; Ahel, Ivan; Palazzo, Luca
PARPs and ADP-ribosyl hydrolases in cancer therapy: From drug targets to biomarkers
2025 Groslambert, Joséphine; Schützenhofer, Kira; Palazzo, Luca; Ahel, Ivan
The DarT/DarG Toxin–Antitoxin ADP-Ribosylation System as a Novel Target for a Rational Design of Innovative Antimicrobial Strategies
2023 Catara, Giuliana; Caggiano, Rocco; Palazzo, Luca
The disruption of the CCDC6 - PP4 axis induces a BRCAness like phenotype and sensitivity to PARP inhibitors in high-grade serous ovarian carcinoma
2022 Morra, Francesco; Merolla, Francesco; Damia, Giovanna; Ricci, Francesca; Varricchio, Silvia; Ilardi, Gennaro; Arenare, Laura; Califano, Daniela; Napolitano, Virginia; Fruscio, Robert; Melillo, Rosa Marina; Palazzo, Luca; Celetti, Angela
Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease
2021 Prokhorov, E; Agnew, T.; Wondisford, Ar; Tellier, M; Kaminski, N; Beijer, D; Holder, J; Groslambert, J; Suskiewicz, Mj; Zhu, K; Reber, Jm; Krassnig, Sc; Palazzo, L; Murphy, S; Nielsen, Ml; Mangerich, A; Ahel, D; Baets, J; O'Sullivan, Rj; Ahel, I
Progress and outlook in studying the substrate specificities of PARPs and related enzymes
2021 Suskiewicz, Mj; Palazzo, L; Hughes, R; Ahel, I
Serine ADP-ribosylation in DNA-damage response regulation
2021 Palazzo, L; Suskiewicz, Mj; Ahel, I
Mono(ADP-ribosyl)ation Enzymes and NAD + Metabolism: A Focus on Diseases and Therapeutic Perspectives
2021 Poltronieri, P.; Celetti, A.; Palazzo, L
(ADP-ribosyl)hydrolases: structure, function, and biology
2020 Rack, Jgm; Palazzo, L; Ahel, I
ADP-ribosylation signalling and human disease
2019 Palazzo, L; Mikolčević, P; Mikoč, A; Ahel, I
CAF-1 Subunits Levels Suggest Combined Treatments with PARP-Inhibitors and Ionizing Radiation in Advanced HNSCC
2019 Morra, Francesco; Merolla, Francesco; Picardi, Ida; Russo, Daniela; Ilardi, Gennaro; Varricchio, Silvia; Liotti, Federica; Pacelli, Roberto; Palazzo, Luca; Mascolo, Massimo; Celetti, Angela; Staibano, Stefania
PARPs and PAR as novel pharmacological targets for the treatment of stress granule-associated disorders
2019 Grimaldi, G; Catara, G; Palazzo, L; Corteggio, A; Valente, C; Corda, D
Targeting ADP-ribosylation as an antimicrobial strategy
2019 Catara, G; Corteggio, A; Valente, C; Grimaldi, G; Palazzo, L
PARPs in genome stability and signal transduction: implications for cancer therapy
2018 Palazzo, L; Ahel, I
MacroD1 Is a Promiscuous ADP-Ribosyl Hydrolase Localized to Mitochondria
2018 Agnew, T; Munnur, D; Crawford, K; Palazzo, L; Mikoč, A; Ahel, I
Serine is the major residue for ADP-ribosylation upon DNA damage
2018 Palazzo, L; Leidecker, O; Prokhorova, E; Dauben, H; Matic, I; Ahel, I.
Studying catabolism of protein ADP-ribosylation
2017 Palazzo, L.; James, D. I.; Waddell, I. D.; Ahel, I.
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| The PARG frontier: mechanisms of PAR turnover and opportunities in precision oncology | 1.8 Articolo in rassegna (review) | 2026 | Catara, Giuliana; Gerace, Gaetano; Lauro, Raffaella; Palazzo, Luca | |
| Histidine and tyrosine residues are targets for SIRT6 ADP-ribosylation activity | 1.1 Articolo in rivista | 2026 | Gregor Matthias Rack, Johannes; Prokhorova, Evgeniia; Lauro, Raffaella; Georgina Kopasz, Anna; Baretić, Domagoj; Raggiaschi, Roberto; Mutabdzija, Jovana; V Filippov, Dmitri; Timinszky, Gyula; Leidecker, Orsolya; Ahel, Ivan; Palazzo, Luca | |
| Expulsion of iron-rich ferritin via CD63-mediated exosome drives ferroptosis resistance in ovarian cancer cells | 1.1 Articolo in rivista | 2025 | Battaglia, A. M.; Sacco, A.; Giorgio, E.; Petriaggi, L.; Elzanowska, J.; Cruz, A. R.; Rocha, L.; Pereira, C. E.; Strano Moraes, M. C.; Palazzo, L.; De Vitis, C.; Costa-Silva, B.; Biamonte, F. | |
| Suppression of ADP-ribosylation reversal triggers cell vulnerability to alkylating agents | 1.1 Articolo in rivista | 2025 | Caggiano, Rocco; Prokhorova, Evgeniia; Duma, Lena; Schützenhofer, Kira; Lauro, Raffaella; Catara, Giuliana; Melillo, Rosa Marina; Celetti, Angela; Smith, Rebecca; Weroha, S John; Kaufmann, Scott H; Ahel, Ivan; Palazzo, Luca | |
| PARPs and ADP-ribosyl hydrolases in cancer therapy: From drug targets to biomarkers | 1.8 Articolo in rassegna (review) | 2025 | Groslambert, Joséphine; Schützenhofer, Kira; Palazzo, Luca; Ahel, Ivan | |
| The DarT/DarG Toxin–Antitoxin ADP-Ribosylation System as a Novel Target for a Rational Design of Innovative Antimicrobial Strategies | 1.1 Articolo in rivista | 2023 | Catara, Giuliana; Caggiano, Rocco; Palazzo, Luca | |
| The disruption of the CCDC6 - PP4 axis induces a BRCAness like phenotype and sensitivity to PARP inhibitors in high-grade serous ovarian carcinoma | 1.1 Articolo in rivista | 2022 | Morra, Francesco; Merolla, Francesco; Damia, Giovanna; Ricci, Francesca; Varricchio, Silvia; Ilardi, Gennaro; Arenare, Laura; Califano, Daniela; Napolitano, Virginia; Fruscio, Robert; Melillo, Rosa Marina; Palazzo, Luca; Celetti, Angela | |
| Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease | 1.1 Articolo in rivista | 2021 | Prokhorov, E; Agnew, T.; Wondisford, Ar; Tellier, M; Kaminski, N; Beijer, D; Holder, J; Groslambert, J; Suskiewicz, Mj; Zhu, K; Reber, Jm; Krassnig, Sc; Palazzo, L; Murphy, S; Nielsen, Ml; Mangerich, A; Ahel, D; Baets, J; O'Sullivan, Rj; Ahel, I | |
| Progress and outlook in studying the substrate specificities of PARPs and related enzymes | 1.8 Articolo in rassegna (review) | 2021 | Suskiewicz, Mj; Palazzo, L; Hughes, R; Ahel, I | |
| Serine ADP-ribosylation in DNA-damage response regulation | 1.8 Articolo in rassegna (review) | 2021 | Palazzo, L; Suskiewicz, Mj; Ahel, I | |
| Mono(ADP-ribosyl)ation Enzymes and NAD + Metabolism: A Focus on Diseases and Therapeutic Perspectives | 1.1 Articolo in rivista | 2021 | Poltronieri, P.; Celetti, A.; Palazzo, L | |
| (ADP-ribosyl)hydrolases: structure, function, and biology | 1.8 Articolo in rassegna (review) | 2020 | Rack, Jgm; Palazzo, L; Ahel, I | |
| ADP-ribosylation signalling and human disease | 1.8 Articolo in rassegna (review) | 2019 | Palazzo, L; Mikolčević, P; Mikoč, A; Ahel, I | |
| CAF-1 Subunits Levels Suggest Combined Treatments with PARP-Inhibitors and Ionizing Radiation in Advanced HNSCC | 1.1 Articolo in rivista | 2019 | Morra, Francesco; Merolla, Francesco; Picardi, Ida; Russo, Daniela; Ilardi, Gennaro; Varricchio, Silvia; Liotti, Federica; Pacelli, Roberto; Palazzo, Luca; Mascolo, Massimo; Celetti, Angela; Staibano, Stefania | |
| PARPs and PAR as novel pharmacological targets for the treatment of stress granule-associated disorders | 1.8 Articolo in rassegna (review) | 2019 | Grimaldi, G; Catara, G; Palazzo, L; Corteggio, A; Valente, C; Corda, D | |
| Targeting ADP-ribosylation as an antimicrobial strategy | 1.8 Articolo in rassegna (review) | 2019 | Catara, G; Corteggio, A; Valente, C; Grimaldi, G; Palazzo, L | |
| PARPs in genome stability and signal transduction: implications for cancer therapy | 1.8 Articolo in rassegna (review) | 2018 | Palazzo, L; Ahel, I | |
| MacroD1 Is a Promiscuous ADP-Ribosyl Hydrolase Localized to Mitochondria | 1.1 Articolo in rivista | 2018 | Agnew, T; Munnur, D; Crawford, K; Palazzo, L; Mikoč, A; Ahel, I | |
| Serine is the major residue for ADP-ribosylation upon DNA damage | 1.1 Articolo in rivista | 2018 | Palazzo, L; Leidecker, O; Prokhorova, E; Dauben, H; Matic, I; Ahel, I. | |
| Studying catabolism of protein ADP-ribosylation | 2.1 Contributo in volume (Capitolo o Saggio) | 2017 | Palazzo, L.; James, D. I.; Waddell, I. D.; Ahel, I. |