IRIS
ZAMPELLA, ANGELA
 Distribuzione geografica
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Continente #
NA - Nord America 3.830
EU - Europa 2.487
AS - Asia 1.650
AF - Africa 74
SA - Sud America 10
Continente sconosciuto - Info sul continente non disponibili 3
OC - Oceania 3
Totale 8.057
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Nazione #
US - Stati Uniti d'America 3.744
IT - Italia 1.354
SG - Singapore 860
CN - Cina 618
FI - Finlandia 290
IE - Irlanda 278
DE - Germania 143
NL - Olanda 115
UA - Ucraina 105
CA - Canada 81
GB - Regno Unito 57
IN - India 51
CI - Costa d'Avorio 48
VN - Vietnam 44
SE - Svezia 39
RU - Federazione Russa 36
MA - Marocco 20
FR - Francia 17
ID - Indonesia 17
JP - Giappone 17
HK - Hong Kong 14
KR - Corea 9
ES - Italia 8
AT - Austria 6
BE - Belgio 6
IR - Iran 6
CH - Svizzera 5
CL - Cile 5
TR - Turchia 5
MX - Messico 4
BG - Bulgaria 3
EG - Egitto 3
PK - Pakistan 3
PT - Portogallo 3
RO - Romania 3
AL - Albania 2
AR - Argentina 2
CZ - Repubblica Ceca 2
DK - Danimarca 2
EU - Europa 2
JE - Jersey 2
KE - Kenya 2
MT - Malta 2
NZ - Nuova Zelanda 2
PL - Polonia 2
A1 - Anonimo 1
AE - Emirati Arabi Uniti 1
AU - Australia 1
BR - Brasile 1
BY - Bielorussia 1
CO - Colombia 1
EE - Estonia 1
GR - Grecia 1
IM - Isola di Man 1
KZ - Kazakistan 1
LI - Liechtenstein 1
MY - Malesia 1
OM - Oman 1
PA - Panama 1
PE - Perù 1
PH - Filippine 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
TW - Taiwan 1
ZA - Sudafrica 1
Totale 8.057
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Città #
Singapore 710
Chandler 647
Santa Clara 323
Naples 291
Millbury 268
Princeton 224
Napoli 196
Nanjing 166
Boston 154
Ashburn 143
Jacksonville 124
Beijing 115
Amsterdam 87
Des Moines 81
Wilmington 80
Ottawa 73
Munich 61
Nanchang 59
Helsinki 57
Shenyang 46
Dong Ket 44
Hebei 43
Lawrence 37
Woodbridge 37
Rome 33
Salerno 33
Pune 31
Jiaxing 30
Torre Annunziata 29
Seattle 28
Tianjin 27
Angri 26
Norwalk 26
Falls Church 24
Houston 24
Ann Arbor 23
Formia 22
Milan 22
Changsha 21
Casablanca 20
Perugia 20
Shanghai 20
Boardman 18
Kronberg 14
Redwood City 14
Jakarta 11
Kunming 10
Los Angeles 10
Bologna 9
Ercolano 9
Bari 8
Dublin 8
Frattamaggiore 8
Hong Kong 8
Lappeenranta 8
Oulu 8
Piemonte 8
Rende 8
Sesto Fiorentino 8
Washington 8
Cagliari 7
Moscow 7
Mountain View 7
Fairfield 6
Lanzhou 6
Orange 6
Redmond 6
Shenzhen 6
Brea 5
Cambridge 5
Indiana 5
Monza 5
Palermo 5
Tokyo 5
Turin 5
Binzhou 4
Caserta 4
Castellammare Di Stabia 4
Chennai 4
Ikari 4
Langhirano 4
Ludhiana 4
Regensburg 4
San Francisco 4
San Leucio 4
South Tangerang 4
Vico Equense 4
Yellow Springs 4
Afragola 3
Ancona 3
Bacoli 3
Boulder 3
Boydton 3
Brescia 3
Brussels 3
Changchun 3
Chions 3
Cosenza 3
Dallas 3
Gaeta 3
Totale 4.874
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Nome #
Guida Ragionata allo Svolgimento di Esercizi di Chimica Organica 109
Characterisation of the dynamic interactions between complex N-glycans and human CD22 99
Discovery of UDCA derivatives as new modulators of bile acid receptors 85
Design, synthesis and pharmacological characterization of novel potent nonsteroidal agonists of the farnesoid X receptor 69
Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists 68
Traduzione-CHIMICA ORGANICA Settima Edizione J. McMURRY 62
Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists 62
Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1 62
Targeting bile acid receptors: discovery of a potent and selective Farnesoid X receptor agonist as a new lead in the pharmacological approach to liver diseases 61
Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury 61
Potent dual agonists of nuclear and membrane bile acid receptors 60
Inspection on bile acid scaffold in the discovery of the first example of LXRa/GPBAR1 dual agonists 59
Harnessing interrupted Fischer in continuous flow: sustainable synthesis of (spiro)indolenine and (spiro)indoline privileged scaffolds 59
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain 59
Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease 59
Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH) 57
Synthesis, Pharmacological Evaluation, and Molecular Modeling Studies of Novel Peptidic CAAX Analogues as Farnesyl-Protein-Transferase Inhibitors 56
Identification of new GPBAR1 selective agonists containing an epoxide group on cholane side chains 56
Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists 55
Bile acids derivatives in the selective modulation of FXR and GP-BAR1 54
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction 54
Design, synthesis, and biological evaluation of potent dual agonists of nuclear and membrane bile acid receptors 53
Synthesis of new isoxazole derivatives as fxr agonists with improved pharmacokinetic properties 53
Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids 52
Concise synthesis of AHMHA unit in perthamide C. Structural and stereochemical revision of perthamide C 52
Marine natural products as modulators of nuclear receptors 52
Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1 52
Modification on Ursodeoxycholic Acid (UDCA) Scaffold. Discovery of Bile Acid Derivatives As Selective Agonists of Cell-Surface G-Protein Coupled Bile Acid Receptor 1 (GP-BAR1) 51
Quantum mechanical calculation of coupling constants in the configurational analysis of flexible systems: determination of the configuration of Callipeltin A 51
Theonella swinhoei as a source of anti-inflammatory cyclopeptides 51
Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties 50
Design and synthesis of hyodeoxycholic acid derivatives as GPBAR1 receptor modulators useful in the treatment of colon inflammation 50
Discovery of a Novel Class of Dual GPBAR1 Agonists-RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders 49
Marine and semi-sinthetic hydroxystroids as new scaffolds for pregnane X receptor modulation 49
Synthesis of a new class of isoxazole derivatives with a dual FXR agonistic and COX-2 inhibitory activity. 49
Callipeltins F-I: new antifungal peptides from the marine sponge Latrunculia sp. 48
Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists 47
Theonellasterols and Conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors 47
Bioactive cembrane derivatives from the Indian Ocean Soft Coral, Sinularia kavarattiensis 47
BAR 501, a Novel GPBAR1 Ligand, Reverses Intestinal and Liver Inflammatory Models Demonstrating That GPBAR1 Is an Essential Modulator of Innate Immunity in Entero-Hepatic Tissues 47
GPBAR1 activation by C6-substituted hyodeoxycholane analogues protect against colitis 47
Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling 46
Plakilactones: a new class of marine agonists of the peroxisome proliferator-activated receptor ??? from Plakinastrella mamillaris 46
BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis 46
Chimica Organica 45
Solomonamides A and B: two unprecedented cyclic peptides from the marine sponge Theonella swinhoei 45
Farnesoid X receptor modulators 2014-present: a patent review 45
The first total synthesis of solomonsterol B, a marine pregnane X receptor agonist 44
Bile acids derivatives in the selective modulation of FXR and GPBAR1 44
Sphinxolides E-G and Redispongiolide C: Four New Cytotoxic Macrolides from the New Caledonian Lithistida Sponges Neosiphonia superstes and Redispongia coerulea 43
Conicasterol E, a small heterodimer partner sparing farnesoid-X-receptor modulator endowed with a pregnane-X-receptor agonistic activity, from the marine sponge Theonella swinhoei 43
Binding mechanism of the farnesoid X receptor marine antagonist suvanine reveals a strategy to forestall drug modulation on nuclear receptors. Design, synthesis, and biological evaluation of novel ligands 43
FXR mediates a chromatin looping in the GR promoter thus promoting the resolution of colitis in rodents 43
Exploitation of Cholane Scaffold for the Discovery of Potent and Selective Farnesoid X Receptor (FXR) and G-Protein Coupled Bile Acid Receptor 1 (GP-BAR1) Ligands 43
Decoding the vasoregulatory activities of bile acid-activated receptors in systemic and portal circulation: Role of gaseous mediators 43
Computer-Aided Drug Design Unveils the Structural Requisites for Bile Acid Receptors Modulation 43
Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity 42
Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands 42
New jaspamide derivatives with antimicrofilament activity from the sponge Jaspis splendans 41
4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity 41
An advanced cellular assay for replicon-based antiviral screening of marine natural products 41
Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonism 41
Rational Drug Design of New Selective Modulators of GPBAR1 41
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1 41
Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics 41
Critical surveys covering the year 2005: total synthesis of natural products 40
Isolation of Plakinamine I: a new steroidal alkaloid from the marine sponge Corticium sp. and synthesis of an analogue model compound 40
Absolute stereochemistry of marine macrolides Reidispongiolide A and Sphinxolide B 40
The First Total Synthesis of Solomonsterol B, a Marine Pregnane X Receptor Agonist 40
Inspection on bile acid scaffold in the discovery of the first example of LXR/GPBAR1 dual agonists 40
Structures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activity 39
Anti-inflammatory cyclopeptides from the marine sponge Theonella swinhoei 39
Synthesis of new bile acids derivatives as selective FXR/GPBAR1 ligands 39
Discovery of cholanoic acid derivatives as new modulators of bile acid receptors 39
Discovery of a new class of GPBAR1 modulators 39
Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis 38
Discovery of Sulfated Sterols from Marine Invertebrates as a New Class of Marine Natural Antagonists of Farnesoid-X-Receptor 38
Epoxide functionalization on cholane side chains in the identification of G-protein coupled bile acid receptor (GPBAR1) selective agonists 38
Synthesis of a new class of isoxazole derivatives with a dual FXR agonistic and COX-2 inhibitory activity 38
Immunomodulatory functions of FXR 37
Perthamide C Inhibits eNOS and iNOS Expression and Has Immunomodulating Activity In Vivo 37
Stereochemical determination of highly flexible systems by quantitative NMR-derived interproton distances combined with quantum mechanical calculations of 13C chemical shifts 37
Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis 37
Synthetic studies on callipeltin A: stereoselective synthesis of (2R,3R,4S)-3-hydroxy-2,4,6- trimethylheptanoic acid 36
Coscinolactams A and B: new nitrogen-containing sesterterpenoids from the marine sponge Coscinoderma mathewsi exerting anti-inflammatory properties 36
Amphiasterins: a new family of cytotoxic metabolites from the marine sponge Plakortis quasiamphiaster 36
Bengamides and related new amino acid derivatives from the New Caledonian marine sponge Jaspis carteri 36
Antiviral and cytotoxic compounds from marine sponges of South Pacific 36
Towards FXR selectivity: manipulation of 6-ethylcholane scaffold 36
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy 36
Isolation of callipeltins A-C and of two new open-chain derivatives of callipeltin A from the marine sponge Latrunculia sp. A revision of the stereostructure of callipeltins. 35
Conicasterol E, a Small Heterodimer Partner Sparing Farnesoid X Receptor Modulator Endowed with a Pregnane X Receptor Agonistic Activity, from the Marine Sponge Theonella swinhoei 35
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists 34
Farnesoid X receptor modulators (2011 - 2014): a patent review 34
Stereochemical assignment of the C23-C35 portion of sphinxolode/reidispongiolide class of natural products by asymmetric synthesis 34
Cytotoxic and antiviral macrolides and cyclopeptides from New Caledonian Lithistida sponges 34
Towards new ligands of nuclear receptors. Discovery of malaitasterol A, an unique bis-secosterol from marine sponge Theonella swinhoei 34
Bile acids activated receptors regulate innate immunity 34
Isolation and structural elucidation of callipeltins J-M: antifungal peptides from the marine sponge Latrunculia sp 33
Stereoselective synthesis of (2R,3R,4R)-3-hydroxy-2,4,6-trimethylheptanoic acid and determination of the absolute stereochemistry of the natural product from Callipeltin A 33
Totale 4.683
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Categoria #
all - tutte 40.047
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.047
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020327 0 0 0 0 0 13 32 37 7 63 107 68
2020/2021651 23 45 58 36 79 117 62 37 74 23 33 64
2021/20221.345 30 11 16 7 16 45 30 64 290 41 163 632
2022/20231.552 278 123 31 148 187 172 21 157 249 88 68 30
2023/20241.208 64 173 142 49 43 109 39 109 46 49 269 116
2024/20251.783 403 551 70 126 146 487 0 0 0 0 0 0
Totale 8.498