CERCHIA, CARMEN
CERCHIA, CARMEN
DIPARTIMENTO DI FARMACIA
Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature
2014 Lavecchia, Antonio; DI GIOVANNI, Carmen; Cerchia, Carmen
Cdc25 inhibitors in melanoma cells
2014 Capasso, Alessandra; Cerchia, Carmen; DI GIOVANNI, Carmen; Granato, Giuseppina; Bertoni, Alessandra; Albano, Francesco; DE VENDITTIS, Emmanuele; Ruocco, MARIA ROSARIA; Lavecchia, Antonio
Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors
2014 Troiano, V; Scarbaci, K; Ettari, R; Micale, N; Cerchia, Carmen; Pinto, A; Schirmeister, T; Novellino, Ettore; Grasso, S; Lavecchia, Antonio; Zappalà, M.
Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents
2014 Scarbaci, K; Troiano, V; Ettari, R; Pinto, A; Micale, N; DI GIOVANNI, Carmen; Cerchia, Carmen; Schirmeister, T; Novellino, Ettore; Lavecchia, Antonio; Zappalà, M; Grasso, S.
Discovery Of Novel Peroxisome Proliferator-Activated Receptor γ (PPARγ) Scaffolds With Partial Agonist Binding Properties By Integrated In Silico/In Vitro Work Flow
2013 Lavecchia, Antonio; DI GIOVANNI, Carmen; Cerchia, Carmen; Laghezza, A.; Tortorella, P.; Loiodice, F.; Novellino, Ettore
Characterization of novel inhibitors of CDC25 phosphatases: biochemical and biological analysis
2017 Nasso, Rosarita; Masullo, Mariorosario; Rullo, Rosario; Simonetti, Martina; Arcucci, Alessandro; Granato, Giuseppina; Cerchia, Carmen; Lavecchia, Antonio; Ruocco, MARIA ROSARIA; DE VENDITTIS, Emmanuele
The antiproliferative and proapoptotic effects of cladosporols A and B are related to their different binding mode as PPARγ ligands
2016 Zurlo, Diana; Ziccardi, Pamela; Votino, Carolina; Colangelo, Tommaso; Cerchia, Carmen; Dal Piaz, Fabrizio; Dallavalle, Sabrina; Moricca, Salvatore; Novellino, Ettore; Lavecchia, Antonio; Colantuoni, Vittorio; Lupo, Angelo
New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity
2017 Piemontese, Luca; Cerchia, Carmen; Laghezza, Antonio; Ziccardi, Pamela; Sblano, Sabina; Tortorella, Paolo; Iacobazzi, Vito; Infantino, Vittoria; Convertini, Paolo; Dal Piaz, Fabrizio; Lupo, Angelo; Colantuoni, Vittorio; Lavecchia, Antonio; Loiodice, Fulvio
Identification of a new series of amides as non-covalent proteasome inhibitors
2014 Scarbaci, K.; Troiano, V.; Micale, N.; Ettari, R.; DI GIOVANNI, Carmen; Cerchia, Carmen; Grasso, S.; Novellino, Ettore; Schirmeister, T.; Lavecchia, Antonio; Zappalà, M.
Small Molecule Drugs And Targeted Therapy For Melanoma: Current Strategies And Future Directions
2017 Cerchia, Carmen; Lavecchia, Antonio
A compound-based proteomic approach discloses 15-ketoatractyligenin methyl ester as a new PPARγ partial agonist with anti-proliferative ability
2017 Vasaturo, Michele; Fiengo, Lorenzo; De Tommasi, Nunziatina; Sabatino, Lina; Ziccardi, Pamela; Colantuoni, Vittorio; Bruno, Maurizio; Cerchia, Carmen; Novellino, Ettore; Lupo, Angelo; Lavecchia, Antonio; Piaz, Fabrizio Dal
Discovery of a Novel Small Molecule Inhibitor Targeting the Frataxin/Ubiquitin Interaction via Structure-Based Virtual Screening and Bioassays
2013 Lavecchia, A.; Di Giovanni, C.; Cerchia, C.; Russo, Annapina; Russo, Giulia; Novellino, E.
Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors: Design, Synthesis, Inhibition Mechanism, and in Vitro Efficacy against Melanoma Cell Lines
2019 Cerchia, Carmen; Nasso, Rosarita; Mori, Matteo; Villa, Stefania; Gelain, Arianna; Capasso, Alessandra; Aliotta, Federica; Simonetti, Martina; Rullo, Rosario; Masullo, Mariorosario; DE VENDITTIS, Emmanuele; Ruocco, MARIA ROSARIA; Lavecchia, Antonio
Ligand-based chemoinformatic discovery of a novel small molecule inhibitor targeting CDC25 dual specificity phosphatases and displaying in vitro efficacy against melanoma cells
2015 Capasso, Alessandra; Cerchia, Carmen; Di Giovanni, Carmen; Granato, Giuseppina; Albano, Francesco; Romano, Simona; De Vendittis, Emmanuele; Ruocco, Maria Rosaria; Lavecchia, Antonio
App maturation and intracellular localization are controlled by a specific inhibitor of 37/67 kda laminin-1 receptor in neuronal cells
2020 Bhattacharya, A.; Limone, A.; Napolitano, F.; Cerchia, C.; Parisi, S.; Minopoli, G.; Montuori, N.; Lavecchia, A.; Sarnataro, D.
Selective PPARγ modulators for Type 2 diabetes treatment: How far have we come and what does the future hold?
2018 Lavecchia, Antonio; Cerchia, Carmen
Exploring structural relationships between bioactive and commercial chemical space and developing target hypotheses for compound acquisition
2017 Cerchia, Carmen; Dimova, Dilyana; Lavecchia, Antonio; Bajorath, Jürgen
Sulfonimide and amide derivatives as novel PPARα antagonists: Synthesis, antiproliferative activity, and docking studies
2020 Ammazzalorso, A.; Bruno, I.; Florio, R.; de Lellis, L.; Laghezza, A.; Cerchia, C.; de Filippis, B.; Fantacuzzi, M.; Giampietro, L.; Maccallini, C.; Tortorella, P.; Veschi, S.; Loiodice, F.; Lavecchia, A.; Cama, A.; Amoroso, R.
Antitumor agents 7. Synthesis, antiproliferative activity and molecular modeling of new L-lysine-conjugated pyridophenoxazinones as potent DNA-binding ligands and topoisomerase IIα inhibitors
2020 Pedatella, S.; Cerchia, C.; Manfra, M.; Cioce, A.; Bolognese, A.; Lavecchia, A.
Development of novel amides as noncovalent inhibitors of immunoproteasomes
2019 Ettari, R.; Cerchia, C.; Maiorana, S.; Guccione, M.; Novellino, E.; Bitto, A.; Grasso, S.; Lavecchia, A.; Zappala, M.
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature | 1.1 Articolo in rivista | 2014 | Lavecchia, Antonio; DI GIOVANNI, Carmen; Cerchia, Carmen | |
| Cdc25 inhibitors in melanoma cells | 1.5 Abstract in rivista | 2014 | Capasso, Alessandra; Cerchia, Carmen; DI GIOVANNI, Carmen; Granato, Giuseppina; Bertoni, Alessandra; Albano, Francesco; DE VENDITTIS, Emmanuele; Ruocco, MARIA ROSARIA; Lavecchia, Antonio | |
| Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors | 1.1 Articolo in rivista | 2014 | Troiano, V; Scarbaci, K; Ettari, R; Micale, N; Cerchia, Carmen; Pinto, A; Schirmeister, T; Novellino, Ettore; Grasso, S; Lavecchia, Antonio; Zappalà, M. | |
| Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents | 1.1 Articolo in rivista | 2014 | Scarbaci, K; Troiano, V; Ettari, R; Pinto, A; Micale, N; DI GIOVANNI, Carmen; Cerchia, Carmen; Schirmeister, T; Novellino, Ettore; Lavecchia, Antonio; Zappalà, M; Grasso, S. | |
| Discovery Of Novel Peroxisome Proliferator-Activated Receptor γ (PPARγ) Scaffolds With Partial Agonist Binding Properties By Integrated In Silico/In Vitro Work Flow | 4.3 Poster | 2013 | Lavecchia, Antonio; DI GIOVANNI, Carmen; Cerchia, Carmen; Laghezza, A.; Tortorella, P.; Loiodice, F.; Novellino, Ettore | |
| Characterization of novel inhibitors of CDC25 phosphatases: biochemical and biological analysis | 4.2 Abstract in Atti di convegno | 2017 | Nasso, Rosarita; Masullo, Mariorosario; Rullo, Rosario; Simonetti, Martina; Arcucci, Alessandro; Granato, Giuseppina; Cerchia, Carmen; Lavecchia, Antonio; Ruocco, MARIA ROSARIA; DE VENDITTIS, Emmanuele | |
| The antiproliferative and proapoptotic effects of cladosporols A and B are related to their different binding mode as PPARγ ligands | 1.1 Articolo in rivista | 2016 | Zurlo, Diana; Ziccardi, Pamela; Votino, Carolina; Colangelo, Tommaso; Cerchia, Carmen; Dal Piaz, Fabrizio; Dallavalle, Sabrina; Moricca, Salvatore; Novellino, Ettore; Lavecchia, Antonio; Colantuoni, Vittorio; Lupo, Angelo | |
| New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity | 1.1 Articolo in rivista | 2017 | Piemontese, Luca; Cerchia, Carmen; Laghezza, Antonio; Ziccardi, Pamela; Sblano, Sabina; Tortorella, Paolo; Iacobazzi, Vito; Infantino, Vittoria; Convertini, Paolo; Dal Piaz, Fabrizio; Lupo, Angelo; Colantuoni, Vittorio; Lavecchia, Antonio; Loiodice, Fulvio | |
| Identification of a new series of amides as non-covalent proteasome inhibitors | 1.1 Articolo in rivista | 2014 | Scarbaci, K.; Troiano, V.; Micale, N.; Ettari, R.; DI GIOVANNI, Carmen; Cerchia, Carmen; Grasso, S.; Novellino, Ettore; Schirmeister, T.; Lavecchia, Antonio; Zappalà, M. | |
| Small Molecule Drugs And Targeted Therapy For Melanoma: Current Strategies And Future Directions | 1.1 Articolo in rivista | 2017 | Cerchia, Carmen; Lavecchia, Antonio | |
| A compound-based proteomic approach discloses 15-ketoatractyligenin methyl ester as a new PPARγ partial agonist with anti-proliferative ability | 1.1 Articolo in rivista | 2017 | Vasaturo, Michele; Fiengo, Lorenzo; De Tommasi, Nunziatina; Sabatino, Lina; Ziccardi, Pamela; Colantuoni, Vittorio; Bruno, Maurizio; Cerchia, Carmen; Novellino, Ettore; Lupo, Angelo; Lavecchia, Antonio; Piaz, Fabrizio Dal | |
| Discovery of a Novel Small Molecule Inhibitor Targeting the Frataxin/Ubiquitin Interaction via Structure-Based Virtual Screening and Bioassays | 1.1 Articolo in rivista | 2013 | Lavecchia, A.; Di Giovanni, C.; Cerchia, C.; Russo, Annapina; Russo, Giulia; Novellino, E. | |
| Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors: Design, Synthesis, Inhibition Mechanism, and in Vitro Efficacy against Melanoma Cell Lines | 1.1 Articolo in rivista | 2019 | Cerchia, Carmen; Nasso, Rosarita; Mori, Matteo; Villa, Stefania; Gelain, Arianna; Capasso, Alessandra; Aliotta, Federica; Simonetti, Martina; Rullo, Rosario; Masullo, Mariorosario; DE VENDITTIS, Emmanuele; Ruocco, MARIA ROSARIA; Lavecchia, Antonio | |
| Ligand-based chemoinformatic discovery of a novel small molecule inhibitor targeting CDC25 dual specificity phosphatases and displaying in vitro efficacy against melanoma cells | 1.1 Articolo in rivista | 2015 | Capasso, Alessandra; Cerchia, Carmen; Di Giovanni, Carmen; Granato, Giuseppina; Albano, Francesco; Romano, Simona; De Vendittis, Emmanuele; Ruocco, Maria Rosaria; Lavecchia, Antonio | |
| App maturation and intracellular localization are controlled by a specific inhibitor of 37/67 kda laminin-1 receptor in neuronal cells | 1.1 Articolo in rivista | 2020 | Bhattacharya, A.; Limone, A.; Napolitano, F.; Cerchia, C.; Parisi, S.; Minopoli, G.; Montuori, N.; Lavecchia, A.; Sarnataro, D. | |
| Selective PPARγ modulators for Type 2 diabetes treatment: How far have we come and what does the future hold? | 1.1 Articolo in rivista | 2018 | Lavecchia, Antonio; Cerchia, Carmen | |
| Exploring structural relationships between bioactive and commercial chemical space and developing target hypotheses for compound acquisition | 1.1 Articolo in rivista | 2017 | Cerchia, Carmen; Dimova, Dilyana; Lavecchia, Antonio; Bajorath, Jürgen | |
| Sulfonimide and amide derivatives as novel PPARα antagonists: Synthesis, antiproliferative activity, and docking studies | 1.1 Articolo in rivista | 2020 | Ammazzalorso, A.; Bruno, I.; Florio, R.; de Lellis, L.; Laghezza, A.; Cerchia, C.; de Filippis, B.; Fantacuzzi, M.; Giampietro, L.; Maccallini, C.; Tortorella, P.; Veschi, S.; Loiodice, F.; Lavecchia, A.; Cama, A.; Amoroso, R. | |
| Antitumor agents 7. Synthesis, antiproliferative activity and molecular modeling of new L-lysine-conjugated pyridophenoxazinones as potent DNA-binding ligands and topoisomerase IIα inhibitors | 1.1 Articolo in rivista | 2020 | Pedatella, S.; Cerchia, C.; Manfra, M.; Cioce, A.; Bolognese, A.; Lavecchia, A. | |
| Development of novel amides as noncovalent inhibitors of immunoproteasomes | 1.1 Articolo in rivista | 2019 | Ettari, R.; Cerchia, C.; Maiorana, S.; Guccione, M.; Novellino, E.; Bitto, A.; Grasso, S.; Lavecchia, A.; Zappala, M. |