SANTORO, MASSIMO
SANTORO, MASSIMO
DIPARTIMENTO DI MEDICINA MOLECOLARE E BIOTECNOLOGIE MEDICHE
RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho.
2001 Barone, MARIA VITTORIA; Sepe, L; Melillo, ROSA MARINA; Mineo, A; Santelli, G; Monaco, C; Castellone, Md; Tramontano, Donatella; Fusco, Alfredo; Santoro, Massimo
Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma
2002 F., Basolo; R., Giannini; C., Monaco; Melillo, ROSA MARINA; Carlomagno, Francesca; M., Pancrazi; G., Salvatore; G., Chiappetta; F., Pacini; R., Elisei; P., Miccoli; A., Pinchera; Fusco, Alfredo; Santoro, Massimo
The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway.
2002 Pelicci, G; Troglio, F; Bodini, A; Melillo, ROSA MARINA; Pettirossi, V; Coda, L; DE GIUSEPPE, A; Santoro, Massimo; Pelicci, Pg
Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels.
2003 Wang, J; Knauf, Ja; Basu, S; Puxeddu, E; Kuroda, H; Santoro, Massimo; Fusco, Alfredo; Fagin, Ja
The Insulin Receptor Substrate (IRS)-1 recruits Phosphatidylinositol 3-Kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.
2001 Melillo, ROSA MARINA; Carlomagno, Francesca; DE VITA, Gabriella; Formisano, Pietro; Vecchio, Giancarlo; Fusco, Alfredo; Billaud, M.; Santoro, Massimo
The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes
2002 Carlomagno, Francesca; Vitagliano, Donata; Guida, Teresa; Napolitano, M.; Vecchio, Giancarlo; Fusco, Alfredo; Gazit, A.; Levitzki, A.; Santoro, Massimo
The RET receptor: function in development and dysfunction in congenital malformation.
2001 Manie, S; Santoro, Massimo; Fusco, Alfredo; Billaud, M.
RET activation and clinicopathologic features in poorly differentiated thyroid tumors.
2002 Santoro, Massimo; Papotti, M; Chiappetta, G; GARCIA ROSTAN, G; Volante, M; Johnson, C; Camp, Rl; Pentimalli, F; Monaco, C; Herrero, A; Carcangiu, Ml; Fusco, Alfredo
FRA-1 expression in hyperplastic and neoplastic thyroid diseases.
2000 G., Chiappetta; G., Tallini; M. C., De; F., Pentimalli; F. d., Nigris; S., Losito; M., Fedele; S., Battista; P., Verde; Santoro, Massimo; Fusco, Alfredo
The receptor tyrosine kinase RET is a Hsp90 client protein and is degraded upon exposure to 17-AAG.
2009 Santoro, Massimo
Presence of physiologically stimulated RET in adult rat brain: induction of RET expression during nerve regeneration.
1996 Colucci D'Amato, G. L.; D'Alessio, A.; Filliatreau, G.; Florio, T.; Di Giamberardino, L.; Chiappetta, G.; Vecchio, Giancarlo; Fusco, Alfredo; Santoro, Massimo; de Franciscis, V.
The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line.
1993 Santoro, Massimo; Melillo, ROSA MARINA; Grieco, M.; Berlingieri, M. T.; Vecchio, Giancarlo; Fusco, Alfredo
High frequency of activation of tyrosine kinase oncogenes in human papillary thyroid carcinoma
1989 Bongarzone, I.; Pierotti, M.; Monzini, N.; Mondellini, P.; Manenti, G.; Donghi, R.; Pilotti, S.; Grieco, M.; Santoro, Massimo; Fusco, Alfredo; Vecchio, Giancarlo; Della Porta, G.
CHARACTERIZATION OF AN INVERSION ON THE LONG ARM OF CHROMOSOME-10 JUXTAPOSING D10S170 AND RET AND CREATING THE ONCOGENIC SEQUENCE RET PTC
1992 Pierotti, M. A.; Santoro, Massimo; Jenkins, R. B.; Sozzi, G.; Bongarzone, I.; Grieco, M.; Monzini, N.; Miozzo, M.; Herrmann, M. A.; Fusco, Alfredo; Hay, I. D.; DELLA PORTA, G.; Vecchio, Giancarlo
Cloning and characterization of H4 (D10S170), a gene involved in RET rearrangements in vivo.
1994 Grieco, M.; Cerrato, A.; Santoro, Massimo; Fusco, Alfredo; Melillo, ROSA MARINA; Vecchio, Giancarlo
PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas.
1990 Grieco, M.; Santoro, Massimo; Berlingieri, M. T.; Melillo, ROSA MARINA; Donghi, R.; Bongarzone, I.; Pierotti, M. A.; Della Porta, G.; Fusco, Alfredo; Vecchio, Giancarlo
Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma.
1994 Santoro, Massimo; Dathan, N. A.; Berlingieri, M. T.; Bongarzone, I.; Paulin, C.; Grieco, M.; Pierotti, M. A.; Vecchio, Giancarlo; Fusco, Alfredo
Expression of the RET receptor tyrosine kinase and GDNFR-alpha in normal and leukemic human hematopoietic cells and stromal cells of the bone marrow microenvironment.
1997 Gattei, V.; Celetti, A.; Cerrato, A.; Degan, M.; De Iuliis, A.; Rossi, F. M.; Chiappetta, G.; Consales, C.; Improta, S.; Zagonel, V.; Aldinucci, D.; Agosti, V.; Santoro, Massimo; Vecchio, Giancarlo; Pinto, A.; Grieco, M.
The Kirsten murine sarcoma virus induces rat thyroid carcinomas in vivo
1989 Portella, Giuseppe; Ferulano, GIUSEPPE PAOLO; Santoro, Massimo; Grieco, M.; Fusco, Alfredo; Vecchio, Giancarlo
TPA induces a block of differentiation and increases the susceptibility to neoplastic transformation of a rat thyroid epithelial cell line
1998 Portella, Giuseppe; Vitagliano, D; Li, Z; Sferratore, F; Santoro, Massimo; Vecchio, Giancarlo; Fusco, Alfredo
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho. | 1.1 Articolo in rivista | 2001 | Barone, MARIA VITTORIA; Sepe, L; Melillo, ROSA MARINA; Mineo, A; Santelli, G; Monaco, C; Castellone, Md; Tramontano, Donatella; Fusco, Alfredo; Santoro, Massimo | |
| Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma | 1.1 Articolo in rivista | 2002 | F., Basolo; R., Giannini; C., Monaco; Melillo, ROSA MARINA; Carlomagno, Francesca; M., Pancrazi; G., Salvatore; G., Chiappetta; F., Pacini; R., Elisei; P., Miccoli; A., Pinchera; Fusco, Alfredo; Santoro, Massimo | |
| The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway. | 1.1 Articolo in rivista | 2002 | Pelicci, G; Troglio, F; Bodini, A; Melillo, ROSA MARINA; Pettirossi, V; Coda, L; DE GIUSEPPE, A; Santoro, Massimo; Pelicci, Pg | |
| Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels. | 1.1 Articolo in rivista | 2003 | Wang, J; Knauf, Ja; Basu, S; Puxeddu, E; Kuroda, H; Santoro, Massimo; Fusco, Alfredo; Fagin, Ja | |
| The Insulin Receptor Substrate (IRS)-1 recruits Phosphatidylinositol 3-Kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret. | 1.1 Articolo in rivista | 2001 | Melillo, ROSA MARINA; Carlomagno, Francesca; DE VITA, Gabriella; Formisano, Pietro; Vecchio, Giancarlo; Fusco, Alfredo; Billaud, M.; Santoro, Massimo | |
| The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes | 1.1 Articolo in rivista | 2002 | Carlomagno, Francesca; Vitagliano, Donata; Guida, Teresa; Napolitano, M.; Vecchio, Giancarlo; Fusco, Alfredo; Gazit, A.; Levitzki, A.; Santoro, Massimo | |
| The RET receptor: function in development and dysfunction in congenital malformation. | 1.1 Articolo in rivista | 2001 | Manie, S; Santoro, Massimo; Fusco, Alfredo; Billaud, M. | |
| RET activation and clinicopathologic features in poorly differentiated thyroid tumors. | 1.1 Articolo in rivista | 2002 | Santoro, Massimo; Papotti, M; Chiappetta, G; GARCIA ROSTAN, G; Volante, M; Johnson, C; Camp, Rl; Pentimalli, F; Monaco, C; Herrero, A; Carcangiu, Ml; Fusco, Alfredo | |
| FRA-1 expression in hyperplastic and neoplastic thyroid diseases. | 1.1 Articolo in rivista | 2000 | G., Chiappetta; G., Tallini; M. C., De; F., Pentimalli; F. d., Nigris; S., Losito; M., Fedele; S., Battista; P., Verde; Santoro, Massimo; Fusco, Alfredo | |
| The receptor tyrosine kinase RET is a Hsp90 client protein and is degraded upon exposure to 17-AAG. | 8.10 Tesi di Dottorato | 2009 | Santoro, Massimo | |
| Presence of physiologically stimulated RET in adult rat brain: induction of RET expression during nerve regeneration. | 1.1 Articolo in rivista | 1996 | Colucci D'Amato, G. L.; D'Alessio, A.; Filliatreau, G.; Florio, T.; Di Giamberardino, L.; Chiappetta, G.; Vecchio, Giancarlo; Fusco, Alfredo; Santoro, Massimo; de Franciscis, V. | |
| The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line. | 1.1 Articolo in rivista | 1993 | Santoro, Massimo; Melillo, ROSA MARINA; Grieco, M.; Berlingieri, M. T.; Vecchio, Giancarlo; Fusco, Alfredo | |
| High frequency of activation of tyrosine kinase oncogenes in human papillary thyroid carcinoma | 1.1 Articolo in rivista | 1989 | Bongarzone, I.; Pierotti, M.; Monzini, N.; Mondellini, P.; Manenti, G.; Donghi, R.; Pilotti, S.; Grieco, M.; Santoro, Massimo; Fusco, Alfredo; Vecchio, Giancarlo; Della Porta, G. | |
| CHARACTERIZATION OF AN INVERSION ON THE LONG ARM OF CHROMOSOME-10 JUXTAPOSING D10S170 AND RET AND CREATING THE ONCOGENIC SEQUENCE RET PTC | 1.1 Articolo in rivista | 1992 | Pierotti, M. A.; Santoro, Massimo; Jenkins, R. B.; Sozzi, G.; Bongarzone, I.; Grieco, M.; Monzini, N.; Miozzo, M.; Herrmann, M. A.; Fusco, Alfredo; Hay, I. D.; DELLA PORTA, G.; Vecchio, Giancarlo | |
| Cloning and characterization of H4 (D10S170), a gene involved in RET rearrangements in vivo. | 1.1 Articolo in rivista | 1994 | Grieco, M.; Cerrato, A.; Santoro, Massimo; Fusco, Alfredo; Melillo, ROSA MARINA; Vecchio, Giancarlo | |
| PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas. | 1.1 Articolo in rivista | 1990 | Grieco, M.; Santoro, Massimo; Berlingieri, M. T.; Melillo, ROSA MARINA; Donghi, R.; Bongarzone, I.; Pierotti, M. A.; Della Porta, G.; Fusco, Alfredo; Vecchio, Giancarlo | |
| Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma. | 1.1 Articolo in rivista | 1994 | Santoro, Massimo; Dathan, N. A.; Berlingieri, M. T.; Bongarzone, I.; Paulin, C.; Grieco, M.; Pierotti, M. A.; Vecchio, Giancarlo; Fusco, Alfredo | |
| Expression of the RET receptor tyrosine kinase and GDNFR-alpha in normal and leukemic human hematopoietic cells and stromal cells of the bone marrow microenvironment. | 1.1 Articolo in rivista | 1997 | Gattei, V.; Celetti, A.; Cerrato, A.; Degan, M.; De Iuliis, A.; Rossi, F. M.; Chiappetta, G.; Consales, C.; Improta, S.; Zagonel, V.; Aldinucci, D.; Agosti, V.; Santoro, Massimo; Vecchio, Giancarlo; Pinto, A.; Grieco, M. | |
| The Kirsten murine sarcoma virus induces rat thyroid carcinomas in vivo | 1.1 Articolo in rivista | 1989 | Portella, Giuseppe; Ferulano, GIUSEPPE PAOLO; Santoro, Massimo; Grieco, M.; Fusco, Alfredo; Vecchio, Giancarlo | |
| TPA induces a block of differentiation and increases the susceptibility to neoplastic transformation of a rat thyroid epithelial cell line | 1.1 Articolo in rivista | 1998 | Portella, Giuseppe; Vitagliano, D; Li, Z; Sferratore, F; Santoro, Massimo; Vecchio, Giancarlo; Fusco, Alfredo |