PLATELLA, CHIARA
PLATELLA, CHIARA
DIPARTIMENTO DI SCIENZE CHIMICHE
A first-in-class and a fished out anticancer platinum compound:: Cis -[PtCl2(NH3)2] and cis -[PtI2(NH3)2] compared for their reactivity towards DNA model systems
2016 Musumeci, Domenica; Platella, Chiara; Riccardi, Claudia; Merlino, Antonello; Marzo, Tiziano; Massai, Lara; Messori, Luigi; Montesarchio, Daniela
Tuning the polymorphism of the anti-VEGF G-rich V7t1 aptamer by covalent dimeric constructs
2020 Riccardi, C.; Musumeci, D.; Platella, C.; Gaglione, R.; Arciello, A.; Montesarchio, D.
Trifunctionalized naphthalene diimides and dimeric analogues as g-quadruplex-targeting anticancer agents selected by affinity chromatography
2020 Platella, C.; Pirota, V.; Musumeci, D.; Rizzi, F.; Iachettini, S.; Zizza, P.; Biroccio, A.; Freccero, M.; Montesarchio, D.; Doria, F.
Synthesis, DNA binding studies, and antiproliferative activity of novel Pt(II)-complexes with an L-alanyl-based ligand
2020 Riccardi, C.; Capasso, D.; Rozza, G. M.; Platella, C.; Montesarchio, D.; Di Gaetano, S.; Marzo, T.; Pratesi, A.; Messori, L.; Roviello, G. N.; Musumeci, D.
The role of G-quadruplex structures of LIGS-generated aptamers R1.2 and R1.3 in IgM specific recognition
2019 Moccia, Federica; Platella, Chiara; Musumeci, Domenica; Batool, Sana; Zumrut, Hasan; Bradshaw, John; Mallikaratchy, Prabodhika; Montesarchio, Daniela
Antitumour activity of resveratrol on human melanoma cells: A possible mechanism related to its interaction with malignant cell telomerase
2017 Platella, Chiara; Guida, Serena; Bonmassar, Laura; Aquino, Angelo; Bonmassar, Enzo; Ravagnan, Giampiero; Montesarchio, Daniela; Roviello, Giovanni N.; Musumeci, Domenica; Fuggetta, Maria Pia
Fluorescence Sensing Using DNA Aptamers in Cancer Research and Clinical Diagnostics
2017 Musumeci, Domenica; Platella, Chiara; Riccardi, Claudia; Moccia, Federica; Montesarchio, Daniela
G-quadruplex-based aptamers against protein targets in therapy and diagnostics
2017 Platella, Chiara; Riccardi, Claudia; Montesarchio, Daniela; Roviello, Giovanni N.; Musumeci, Domenica
Shedding light on the interaction of polydatin and resveratrol with G-quadruplex and duplex DNA: a biophysical, computational and biological approach
2020 Platella, C.; Raucci, U.; Rega, N.; D'Atri, S.; Levati, L.; Roviello, G. N.; Fuggetta, M. P.; Musumeci, D.; Montesarchio, D.
On the interaction of an anticancer trisubstituted naphthalene diimide with G-quadruplexes of different topologies: a structural insight
2020 Platella, Chiara; Trajkovski, Marko; Doria, Filippo; Freccero, Mauro; Plavec, Janez; Montesarchio, Daniela
Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes
2017 Musumeci, Domenica; Amato, Jussara; Zizza, Pasquale; Platella, Chiara; Cosconati, Sandro; Cingolani, Chiara; Biroccio, Annamaria; Novellino, Ettore; Randazzo, Antonio; Giancola, Concetta; Pagano, Bruno; Montesarchio, Daniela
Tailoring a lead-like compound targeting multiple G-quadruplex structures
2019 Amato, Jussara; Platella, Chiara; Iachettini, Sara; Zizza, Pasquale; Musumeci, Domenica; Cosconati, Sandro; Pagano, Alessia; Novellino, Ettore; Biroccio, Annamaria; Randazzo, Antonio; Pagano, Bruno; Montesarchio, Daniela
On the binding of naphthalene diimides to a human telomeric G-quadruplex multimer model
2021 Pirota, V.; Platella, C.; Musumeci, D.; Benassi, A.; Amato, J.; Pagano, B.; Colombo, G.; Freccero, M.; Doria, F.; Montesarchio, D.
Metodo per la preparazione di un supporto a basso legame aspecifico per cromatografia di affinità e/o sintesi diretta di oligonucleotidi
2017 Platella, Chiara; Musumeci, Domenica; Amato, Jussara; Randazzo, Antonio; Pagano, Bruno; Montesarchio, Daniela
Method for the preparation of a low unspecific binding-support for affinity chromatography and/or on-line synthesis of oligonucleotides
2018 Platella, Chiara; Musumeci, Domenica; Amato, Jussara; Randazzo, Antonio; Pagano, Bruno; Montesarchio, Daniela
Controlled Pore Glass-based oligonucleotide affinity support: towards High Throughput Screening methods for the identification of conformation-selective G-quadruplex ligands
2018 Platella, Chiara; Musumeci, Domenica; Arciello, Angela; Doria, Filippo; Freccero, Mauro; Randazzo, Antonio; Amato, Jussara; Pagano, Bruno; Montesarchio, Daniela
G-quadruplex-based aptamers targeting human thrombin: Discovery, chemical modifications and antithrombotic effects
2021 Riccardi, C.; Napolitano, E.; Platella, C.; Musumeci, D.; Montesarchio, D.
Anti-VEGF DNA-based aptamers in cancer therapeutics and diagnostics
2021 Riccardi, Claudia; Napolitano, Ettore; Platella, Chiara; Musumeci, Domenica; Melone, Mariarosa A. B.; Montesarchio, Daniela
Disentangling the Structure-Activity Relationships of Naphthalene Diimides as Anticancer G-Quadruplex-Targeting Drugs
2021 Platella, C; Napolitano, E; Riccardi, C; Musumeci, D; Montesarchio, D.
Interference of polydatin/resveratrol in the ACE2:Spike recognition during COVID-19 infection. a focus on their potential mechanism of action through computational and biochemical assays
2021 Perrella, F.; Coppola, F.; Petrone, A.; Platella, C.; Montesarchio, D.; Stringaro, A.; Ravagnan, G.; Fuggetta, M. P.; Rega, N.; Musumeci, D.
Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
---|---|---|---|---|
A first-in-class and a fished out anticancer platinum compound:: Cis -[PtCl2(NH3)2] and cis -[PtI2(NH3)2] compared for their reactivity towards DNA model systems | 1.1 Articolo in rivista | 2016 | Musumeci, Domenica; Platella, Chiara; Riccardi, Claudia; Merlino, Antonello; Marzo, Tiziano; Massai, Lara; Messori, Luigi; Montesarchio, Daniela | |
Tuning the polymorphism of the anti-VEGF G-rich V7t1 aptamer by covalent dimeric constructs | 1.1 Articolo in rivista | 2020 | Riccardi, C.; Musumeci, D.; Platella, C.; Gaglione, R.; Arciello, A.; Montesarchio, D. | |
Trifunctionalized naphthalene diimides and dimeric analogues as g-quadruplex-targeting anticancer agents selected by affinity chromatography | 1.1 Articolo in rivista | 2020 | Platella, C.; Pirota, V.; Musumeci, D.; Rizzi, F.; Iachettini, S.; Zizza, P.; Biroccio, A.; Freccero, M.; Montesarchio, D.; Doria, F. | |
Synthesis, DNA binding studies, and antiproliferative activity of novel Pt(II)-complexes with an L-alanyl-based ligand | 1.1 Articolo in rivista | 2020 | Riccardi, C.; Capasso, D.; Rozza, G. M.; Platella, C.; Montesarchio, D.; Di Gaetano, S.; Marzo, T.; Pratesi, A.; Messori, L.; Roviello, G. N.; Musumeci, D. | |
The role of G-quadruplex structures of LIGS-generated aptamers R1.2 and R1.3 in IgM specific recognition | 1.1 Articolo in rivista | 2019 | Moccia, Federica; Platella, Chiara; Musumeci, Domenica; Batool, Sana; Zumrut, Hasan; Bradshaw, John; Mallikaratchy, Prabodhika; Montesarchio, Daniela | |
Antitumour activity of resveratrol on human melanoma cells: A possible mechanism related to its interaction with malignant cell telomerase | 1.1 Articolo in rivista | 2017 | Platella, Chiara; Guida, Serena; Bonmassar, Laura; Aquino, Angelo; Bonmassar, Enzo; Ravagnan, Giampiero; Montesarchio, Daniela; Roviello, Giovanni N.; Musumeci, Domenica; Fuggetta, Maria Pia | |
Fluorescence Sensing Using DNA Aptamers in Cancer Research and Clinical Diagnostics | 1.1 Articolo in rivista | 2017 | Musumeci, Domenica; Platella, Chiara; Riccardi, Claudia; Moccia, Federica; Montesarchio, Daniela | |
G-quadruplex-based aptamers against protein targets in therapy and diagnostics | 1.1 Articolo in rivista | 2017 | Platella, Chiara; Riccardi, Claudia; Montesarchio, Daniela; Roviello, Giovanni N.; Musumeci, Domenica | |
Shedding light on the interaction of polydatin and resveratrol with G-quadruplex and duplex DNA: a biophysical, computational and biological approach | 1.1 Articolo in rivista | 2020 | Platella, C.; Raucci, U.; Rega, N.; D'Atri, S.; Levati, L.; Roviello, G. N.; Fuggetta, M. P.; Musumeci, D.; Montesarchio, D. | |
On the interaction of an anticancer trisubstituted naphthalene diimide with G-quadruplexes of different topologies: a structural insight | 1.1 Articolo in rivista | 2020 | Platella, Chiara; Trajkovski, Marko; Doria, Filippo; Freccero, Mauro; Plavec, Janez; Montesarchio, Daniela | |
Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes | 1.1 Articolo in rivista | 2017 | Musumeci, Domenica; Amato, Jussara; Zizza, Pasquale; Platella, Chiara; Cosconati, Sandro; Cingolani, Chiara; Biroccio, Annamaria; Novellino, Ettore; Randazzo, Antonio; Giancola, Concetta; Pagano, Bruno; Montesarchio, Daniela | |
Tailoring a lead-like compound targeting multiple G-quadruplex structures | 1.1 Articolo in rivista | 2019 | Amato, Jussara; Platella, Chiara; Iachettini, Sara; Zizza, Pasquale; Musumeci, Domenica; Cosconati, Sandro; Pagano, Alessia; Novellino, Ettore; Biroccio, Annamaria; Randazzo, Antonio; Pagano, Bruno; Montesarchio, Daniela | |
On the binding of naphthalene diimides to a human telomeric G-quadruplex multimer model | 1.1 Articolo in rivista | 2021 | Pirota, V.; Platella, C.; Musumeci, D.; Benassi, A.; Amato, J.; Pagano, B.; Colombo, G.; Freccero, M.; Doria, F.; Montesarchio, D. | |
Metodo per la preparazione di un supporto a basso legame aspecifico per cromatografia di affinità e/o sintesi diretta di oligonucleotidi | 6.1 Brevetto | 2017 | Platella, Chiara; Musumeci, Domenica; Amato, Jussara; Randazzo, Antonio; Pagano, Bruno; Montesarchio, Daniela | |
Method for the preparation of a low unspecific binding-support for affinity chromatography and/or on-line synthesis of oligonucleotides | 6.1 Brevetto | 2018 | Platella, Chiara; Musumeci, Domenica; Amato, Jussara; Randazzo, Antonio; Pagano, Bruno; Montesarchio, Daniela | |
Controlled Pore Glass-based oligonucleotide affinity support: towards High Throughput Screening methods for the identification of conformation-selective G-quadruplex ligands | 1.1 Articolo in rivista | 2018 | Platella, Chiara; Musumeci, Domenica; Arciello, Angela; Doria, Filippo; Freccero, Mauro; Randazzo, Antonio; Amato, Jussara; Pagano, Bruno; Montesarchio, Daniela | |
G-quadruplex-based aptamers targeting human thrombin: Discovery, chemical modifications and antithrombotic effects | 1.1 Articolo in rivista | 2021 | Riccardi, C.; Napolitano, E.; Platella, C.; Musumeci, D.; Montesarchio, D. | |
Anti-VEGF DNA-based aptamers in cancer therapeutics and diagnostics | 1.1 Articolo in rivista | 2021 | Riccardi, Claudia; Napolitano, Ettore; Platella, Chiara; Musumeci, Domenica; Melone, Mariarosa A. B.; Montesarchio, Daniela | |
Disentangling the Structure-Activity Relationships of Naphthalene Diimides as Anticancer G-Quadruplex-Targeting Drugs | 1.1 Articolo in rivista | 2021 | Platella, C; Napolitano, E; Riccardi, C; Musumeci, D; Montesarchio, D. | |
Interference of polydatin/resveratrol in the ACE2:Spike recognition during COVID-19 infection. a focus on their potential mechanism of action through computational and biochemical assays | 1.1 Articolo in rivista | 2021 | Perrella, F.; Coppola, F.; Petrone, A.; Platella, C.; Montesarchio, D.; Stringaro, A.; Ravagnan, G.; Fuggetta, M. P.; Rega, N.; Musumeci, D. |