FIORILLO, BIANCA
FIORILLO, BIANCA
DIPARTIMENTO DI FARMACIA
Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain
2020 Carino, A; Moraca, F; Fiorillo, B; Marchianò, S; Sepe, V; Biagioli, M; Finamore, C; Bozza, S; Francisci, D; Distrutti, E; Catalanotti, B; Zampella, A; Fiorucci, S
Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1
2021 Fiorillo, B.; Sepe, V.; Conflitti, P.; Roselli, R.; Biagioli, M.; Marchiano, S.; De Luca, P.; Baronissi, G.; Rapacciuolo, P.; Cassiano, C.; Catalanotti, B.; Zampella, A.; Limongelli, V.; Fiorucci, S.
Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction
2021 Biagioli, M.; Marchiano, S.; Roselli, R.; Di Giorgio, C.; Bellini, R.; Bordoni, M.; Gidari, A.; Sabbatini, S.; Francisci, D.; Fiorillo, B.; Catalanotti, B.; Distrutti, E.; Carino, A.; Zampella, A.; Costantino, G.; Fiorucci, S.
Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics
2022 Fiorillo, Bianca; Marchianò, Silvia; Moraca, Federica; Sepe, Valentina; Carino, Adriana; Rapacciuolo, Pasquale; Biagioli, Michele; Limongelli, Vittorio; Zampella, Angela; Catalanotti, Bruno; Fiorucci, Stefano
Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease
2022 Fiorucci, Stefano; Rapacciuolo, Pasquale; Fiorillo, Bianca; Roselli, Rosalinda; Marchianò, Silvia; Di Giorgio, Cristina; Bordoni, Martina; Bellini, Rachele; Cassiano, Chiara; Conflitti, Paolo; Catalanotti, Bruno; Limongelli, Vittorio; Sepe, Valentina; Biagioli, Michele; Zampella, Angela
Combinatorial targeting of G-protein-coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug-induced liver injury
2022 Biagioli, M.; Marchiano, S.; di Giorgio, C.; Roselli, R.; Bordoni, M.; Bellini, R.; Fiorillo, B.; Sepe, Valentina; Catalanotti, B.; Cassiano, C.; Monti, M. C.; Distrutti, E.; Zampella, Angela; Fiorucci, S.
Molecular Basis for Non-Covalent, Non-Competitive FAAH Inhibition
2022 Morgillo, CARMINE MARCO; Lupia, Antonio; Deplano, Alessandro; Pirone, Luciano; Fiorillo, Bianca; Pedone, Emilia; Javier Luque, F.; Onnis, Valentina; Moraca, Federica; Catalanotti, Bruno
Discovery of a Novel Class of Dual GPBAR1 Agonists-RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders
2023 Fiorillo, B.; Roselli, R.; Finamore, C.; Biagioli, M.; di Giorgio, C.; Bordoni, M.; Conflitti, P.; Marchiano, S.; Bellini, R.; Rapacciuolo, P.; Cassiano, C.; Limongelli, V.; Sepe, V.; Catalanotti, B.; Fiorucci, S.; Zampella, A.
Hijacking SARS-Cov-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on receptor binding region
2020 Carino, Adriana; Moraca, Federica; Fiorillo, Bianca; Marcan('(o)), Silvia; Sepe, Valentina; Biagioli, Michele; Finamore, Claudia; Bozza, Silvia; Francisci, Daniela; Distrutti, Eleonora; Catalanotti, Bruno; Zampella, Angela; Fiorucci, Stefano
The TBC1D31/praja2 complex controls primary ciliogenesis through PKA-directed OFD1 ubiquitylation
2021 Senatore, E.; Chiuso, F.; Rinaldi, L.; Intartaglia, D.; Delle Donne, R.; Pedone, E.; Catalanotti, B.; Pirone, L.; Moraca, F.; Giamundo, G.; Scala, G.; Raffeiner, A.; Torres-Quesada, O.; Stefan, E.; Kwiatkowski, M.; van Pijkeren, A.; Morleo, M.; Franco, B.; Garbi, C.; Conte, I.; Feliciello, A.; Fiorillo, B.
Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders
2023 Fiorucci, Stefano; Sepe, Valentina; Biagioli, Michele; Fiorillo, Bianca; Rapacciuolo, Pasquale; Distrutti, Eleonora; Zampella, Angela
AI-assisted de novo design of selective k-opioid receptor antagonists for the treatment of opioid addiction
2022 Salas Estrada, Letty Leslie Ann; Provasi, Davide; Lamim Ribeiro, Joao Marcelo; Fiorillo, Bianca; Filizola, Marta
Allosteric communication across the μ-opioid receptor-Gi1 protein complex induced by ligands of varying efficacy
2024 Fiorillo, Bianca; Ghosh, Rikhia; Konovalov, Kirill; Provasi, Davide; Filizola, Marta
Metadynamics simulations leveraged by statistical analyses and artificial intelligence-based tools to inform the discovery of G protein-coupled receptor ligands
2022 Salas-Estrada, L; Fiorillo, B; Filizola, M.
Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders”
2023 Fiorillo, Bianca; Roselli, Rosalinda; Finamore, Claudia; Biagioli, Michele; di Giorgio, Cristina; Bordoni, Martina; Conflitti, Paolo; Marchianò, Silvia; Bellini, Rachele; Rapacciuolo, Pasquale; Cassiano, Chiara; Limongelli, Vittorio; Sepe, Valentina; Catalanotti, Bruno; Fiorucci, Stefano; Zampella, Angela
Computational characterization of the binding mode and mechanism of action of tricyclic small molecules at 5-HT1E and 5-HT1F receptors
2023 Fiorillo, Bianca; Zilberg, Gregory; Wacker, Daniel; Filizola, Marta
Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT1eR and 5-HT1FR
2024 Zilberg, G; Parpounas, Ak; Warren, Al; Fiorillo, B; Provasi, D; Filizola, M; Wacker, D.
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists
2023 Finamore, Claudia; Festa, Carmen; Fiorillo, Bianca; Di Leva, Francesco Saverio; Roselli, Rosalinda; Marchianò, Silvia; Biagioli, Michele; Spinelli, Lucio; Fiorucci, Stefano; Limongelli, Vittorio; Zampella, Angela; DE MARINO, Simona
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| Hijacking SARS-CoV-2/ACE2 Receptor Interaction by Natural and Semi-synthetic Steroidal Agents Acting on Functional Pockets on the Receptor Binding Domain | 1.1 Articolo in rivista | 2020 | Carino, A; Moraca, F; Fiorillo, B; Marchianò, S; Sepe, V; Biagioli, M; Finamore, C; Bozza, S; Francisci, D; Distrutti, E; Catalanotti, B; Zampella, A; Fiorucci, S | |
| Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1 | 1.1 Articolo in rivista | 2021 | Fiorillo, B.; Sepe, V.; Conflitti, P.; Roselli, R.; Biagioli, M.; Marchiano, S.; De Luca, P.; Baronissi, G.; Rapacciuolo, P.; Cassiano, C.; Catalanotti, B.; Zampella, A.; Limongelli, V.; Fiorucci, S. | |
| Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction | 1.1 Articolo in rivista | 2021 | Biagioli, M.; Marchiano, S.; Roselli, R.; Di Giorgio, C.; Bellini, R.; Bordoni, M.; Gidari, A.; Sabbatini, S.; Francisci, D.; Fiorillo, B.; Catalanotti, B.; Distrutti, E.; Carino, A.; Zampella, A.; Costantino, G.; Fiorucci, S. | |
| Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics | 1.1 Articolo in rivista | 2022 | Fiorillo, Bianca; Marchianò, Silvia; Moraca, Federica; Sepe, Valentina; Carino, Adriana; Rapacciuolo, Pasquale; Biagioli, Michele; Limongelli, Vittorio; Zampella, Angela; Catalanotti, Bruno; Fiorucci, Stefano | |
| Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease | 1.1 Articolo in rivista | 2022 | Fiorucci, Stefano; Rapacciuolo, Pasquale; Fiorillo, Bianca; Roselli, Rosalinda; Marchianò, Silvia; Di Giorgio, Cristina; Bordoni, Martina; Bellini, Rachele; Cassiano, Chiara; Conflitti, Paolo; Catalanotti, Bruno; Limongelli, Vittorio; Sepe, Valentina; Biagioli, Michele; Zampella, Angela | |
| Combinatorial targeting of G-protein-coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug-induced liver injury | 1.1 Articolo in rivista | 2022 | Biagioli, M.; Marchiano, S.; di Giorgio, C.; Roselli, R.; Bordoni, M.; Bellini, R.; Fiorillo, B.; Sepe, Valentina; Catalanotti, B.; Cassiano, C.; Monti, M. C.; Distrutti, E.; Zampella, Angela; Fiorucci, S. | |
| Molecular Basis for Non-Covalent, Non-Competitive FAAH Inhibition | 1.1 Articolo in rivista | 2022 | Morgillo, CARMINE MARCO; Lupia, Antonio; Deplano, Alessandro; Pirone, Luciano; Fiorillo, Bianca; Pedone, Emilia; Javier Luque, F.; Onnis, Valentina; Moraca, Federica; Catalanotti, Bruno | |
| Discovery of a Novel Class of Dual GPBAR1 Agonists-RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders | 1.1 Articolo in rivista | 2023 | Fiorillo, B.; Roselli, R.; Finamore, C.; Biagioli, M.; di Giorgio, C.; Bordoni, M.; Conflitti, P.; Marchiano, S.; Bellini, R.; Rapacciuolo, P.; Cassiano, C.; Limongelli, V.; Sepe, V.; Catalanotti, B.; Fiorucci, S.; Zampella, A. | |
| Hijacking SARS-Cov-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on receptor binding region | 1.1 Articolo in rivista | 2020 | Carino, Adriana; Moraca, Federica; Fiorillo, Bianca; Marcan('(o)), Silvia; Sepe, Valentina; Biagioli, Michele; Finamore, Claudia; Bozza, Silvia; Francisci, Daniela; Distrutti, Eleonora; Catalanotti, Bruno; Zampella, Angela; Fiorucci, Stefano | |
| The TBC1D31/praja2 complex controls primary ciliogenesis through PKA-directed OFD1 ubiquitylation | 1.1 Articolo in rivista | 2021 | Senatore, E.; Chiuso, F.; Rinaldi, L.; Intartaglia, D.; Delle Donne, R.; Pedone, E.; Catalanotti, B.; Pirone, L.; Moraca, F.; Giamundo, G.; Scala, G.; Raffeiner, A.; Torres-Quesada, O.; Stefan, E.; Kwiatkowski, M.; van Pijkeren, A.; Morleo, M.; Franco, B.; Garbi, C.; Conte, I.; Feliciello, A.; Fiorillo, B. | |
| Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders | 1.1 Articolo in rivista | 2023 | Fiorucci, Stefano; Sepe, Valentina; Biagioli, Michele; Fiorillo, Bianca; Rapacciuolo, Pasquale; Distrutti, Eleonora; Zampella, Angela | |
| AI-assisted de novo design of selective k-opioid receptor antagonists for the treatment of opioid addiction | 1.5 Abstract in rivista | 2022 | Salas Estrada, Letty Leslie Ann; Provasi, Davide; Lamim Ribeiro, Joao Marcelo; Fiorillo, Bianca; Filizola, Marta | |
| Allosteric communication across the μ-opioid receptor-Gi1 protein complex induced by ligands of varying efficacy | 1.5 Abstract in rivista | 2024 | Fiorillo, Bianca; Ghosh, Rikhia; Konovalov, Kirill; Provasi, Davide; Filizola, Marta | |
| Metadynamics simulations leveraged by statistical analyses and artificial intelligence-based tools to inform the discovery of G protein-coupled receptor ligands | 1.1 Articolo in rivista | 2022 | Salas-Estrada, L; Fiorillo, B; Filizola, M. | |
| Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders” | 1.7 Commento, erratum, replica e simili | 2023 | Fiorillo, Bianca; Roselli, Rosalinda; Finamore, Claudia; Biagioli, Michele; di Giorgio, Cristina; Bordoni, Martina; Conflitti, Paolo; Marchianò, Silvia; Bellini, Rachele; Rapacciuolo, Pasquale; Cassiano, Chiara; Limongelli, Vittorio; Sepe, Valentina; Catalanotti, Bruno; Fiorucci, Stefano; Zampella, Angela | |
| Computational characterization of the binding mode and mechanism of action of tricyclic small molecules at 5-HT1E and 5-HT1F receptors | 1.5 Abstract in rivista | 2023 | Fiorillo, Bianca; Zilberg, Gregory; Wacker, Daniel; Filizola, Marta | |
| Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT1eR and 5-HT1FR | 1.1 Articolo in rivista | 2024 | Zilberg, G; Parpounas, Ak; Warren, Al; Fiorillo, B; Provasi, D; Filizola, M; Wacker, D. | |
| Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists | 1.1 Articolo in rivista | 2023 | Finamore, Claudia; Festa, Carmen; Fiorillo, Bianca; Di Leva, Francesco Saverio; Roselli, Rosalinda; Marchianò, Silvia; Biagioli, Michele; Spinelli, Lucio; Fiorucci, Stefano; Limongelli, Vittorio; Zampella, Angela; DE MARINO, Simona |