Antimalarial agents having a novel pharmacophore of formula (I) are herein described. These polycyclic compounds are able to inhibit chloroquine-sensitive and chloroquine-resistant strains ofPlasmodium falciparum (Pf). Furthermore, the synthesis of these compounds involves few steps from commercial products with low cost of production.
Preparation of imidazole derivatives as antimalarial agents / G., Campiani; S., Gemma; Fattorusso, Caterina; G., Kukreja; B. P., Joshi; TAGLIALATELA SCAFATI, Orazio; L., Savini; M., DE ANGELIS; Fattorusso, Ernesto. - (2007).
Preparation of imidazole derivatives as antimalarial agents
FATTORUSSO, CATERINA;TAGLIALATELA SCAFATI, ORAZIO;FATTORUSSO, ERNESTO
2007
Abstract
Antimalarial agents having a novel pharmacophore of formula (I) are herein described. These polycyclic compounds are able to inhibit chloroquine-sensitive and chloroquine-resistant strains ofPlasmodium falciparum (Pf). Furthermore, the synthesis of these compounds involves few steps from commercial products with low cost of production.File in questo prodotto:
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