The efficacy and safety of renin angiotensin system (RAS) inhibition for lowering blood pressure in older populations has been demonstrated in a number of clinical trials. Whether a patient’s age influences the overall ability of these drugs to lower blood pressure and protect against progress of cardiovascular and kidney disease has been the focus of few clinical trials. Herein, we review the mechanism of action of the renin angiotensin cascade and then discuss the clinical evidence surrounding the use of RAS-blocking drugs in the older population.
Valsartan improves maximal exercise capacity in elderly hypertensives: results of a randomized, placebo-controlled crossover trial / DE ROSA, MARIA LEONARDA. - (2010). (Intervento presentato al convegno The 23rd scientific meeting of the International Society of Hypertension tenutosi a Vancouver,Canada nel September 26-30/2010).
Valsartan improves maximal exercise capacity in elderly hypertensives: results of a randomized, placebo-controlled crossover trial
DE ROSA, MARIA LEONARDA
2010
Abstract
The efficacy and safety of renin angiotensin system (RAS) inhibition for lowering blood pressure in older populations has been demonstrated in a number of clinical trials. Whether a patient’s age influences the overall ability of these drugs to lower blood pressure and protect against progress of cardiovascular and kidney disease has been the focus of few clinical trials. Herein, we review the mechanism of action of the renin angiotensin cascade and then discuss the clinical evidence surrounding the use of RAS-blocking drugs in the older population.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
