Recently we presented a prototype for fluorescence and radionuclide planar imaging system in small animals and its use in the analysis of solid surface tumors was assessed. The optical part is based on the detection of the red fluorescence radiation emitted by a hematoporphyrin (HP) compound injected systemically in the mice and accumulated in tumors, under green light illumination of the mouse body. Here we report on the improvement we made on the optical system, by using a high-sensitivity cooled CCD camera and optical magnification via a stereomicroscope.
Haematoporphyrin mediated laser induced fluorescence in vivoimaging of tumor and organs in small animals / Autiero, M.; Celentano, Luigi; Cozzolino, R.; Laccetti, P.; Marotta, M.; Mettivier, Giovanni; Montesi, M. C.; Riccio, P.; Roberti, G.; Russo, Paolo. - (2004), pp. 3743-3747. (Intervento presentato al convegno IEEE Nucl. Sci. Symp. and Medical Imaging Conference tenutosi a Roma nel Ottobre 16-22, 2004) [10.1109/NSSMIC.2004.1466694].
Haematoporphyrin mediated laser induced fluorescence in vivoimaging of tumor and organs in small animals
CELENTANO, LUIGI;METTIVIER, GIOVANNI;M. C. MONTESI;G. ROBERTI;RUSSO, PAOLO
2004
Abstract
Recently we presented a prototype for fluorescence and radionuclide planar imaging system in small animals and its use in the analysis of solid surface tumors was assessed. The optical part is based on the detection of the red fluorescence radiation emitted by a hematoporphyrin (HP) compound injected systemically in the mice and accumulated in tumors, under green light illumination of the mouse body. Here we report on the improvement we made on the optical system, by using a high-sensitivity cooled CCD camera and optical magnification via a stereomicroscope.File | Dimensione | Formato | |
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