The validation of new metal-based agents for the cancer therapy, in particular the ruthenium complex inspired to the drug NAMI-A, AziRu. Its pharmacokinetic profile was improved by the inclusion in liposomes. The validation was performed by evaluation of biocompatibility and cellular uptake of different types of liposomes. Moreover were analyzed the cell death pathways induced by these compounds.
In vitro biological characterization of innovative anticancer metal-based agents / Santamaria, R.. - (2016).
In vitro biological characterization of innovative anticancer metal-based agents
SANTAMARIA, RITA
2016
Abstract
The validation of new metal-based agents for the cancer therapy, in particular the ruthenium complex inspired to the drug NAMI-A, AziRu. Its pharmacokinetic profile was improved by the inclusion in liposomes. The validation was performed by evaluation of biocompatibility and cellular uptake of different types of liposomes. Moreover were analyzed the cell death pathways induced by these compounds.File in questo prodotto:
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