IRIS
FUSCO, ALFREDO
 Distribuzione geografica
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Continente #
AS - Asia 18.053
NA - Nord America 16.692
EU - Europa 11.813
SA - Sud America 2.373
AF - Africa 412
OC - Oceania 21
Continente sconosciuto - Info sul continente non disponibili 5
Totale 49.369
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Nazione #
US - Stati Uniti d'America 16.033
SG - Singapore 8.487
RU - Federazione Russa 5.473
VN - Vietnam 3.258
CN - Cina 3.034
BR - Brasile 1.930
HK - Hong Kong 1.602
IT - Italia 1.256
DE - Germania 819
UA - Ucraina 774
FI - Finlandia 689
FR - Francia 644
IE - Irlanda 640
SE - Svezia 413
CA - Canada 393
NL - Olanda 379
GB - Regno Unito 344
IN - India 289
JP - Giappone 241
BD - Bangladesh 204
AR - Argentina 157
MX - Messico 152
IQ - Iraq 134
ZA - Sudafrica 129
PH - Filippine 116
EC - Ecuador 92
PL - Polonia 88
ID - Indonesia 82
TH - Thailandia 80
CI - Costa d'Avorio 74
KR - Corea 73
ES - Italia 72
TR - Turchia 64
PK - Pakistan 55
AT - Austria 51
VE - Venezuela 48
CO - Colombia 43
IR - Iran 33
PY - Paraguay 33
LT - Lituania 32
CL - Cile 30
MA - Marocco 30
TW - Taiwan 30
KE - Kenya 29
UZ - Uzbekistan 29
JO - Giordania 27
AE - Emirati Arabi Uniti 25
EG - Egitto 24
JM - Giamaica 24
SA - Arabia Saudita 24
CZ - Repubblica Ceca 23
AZ - Azerbaigian 22
DZ - Algeria 21
IL - Israele 18
DO - Repubblica Dominicana 17
OM - Oman 17
BE - Belgio 15
TN - Tunisia 15
KZ - Kazakistan 14
PE - Perù 14
AU - Australia 12
LB - Libano 12
AL - Albania 11
BO - Bolivia 11
CR - Costa Rica 11
ET - Etiopia 11
KG - Kirghizistan 11
MY - Malesia 11
NP - Nepal 11
RO - Romania 11
UY - Uruguay 11
HU - Ungheria 10
BB - Barbados 9
GE - Georgia 9
HN - Honduras 9
SN - Senegal 9
GT - Guatemala 8
AO - Angola 7
NG - Nigeria 7
NI - Nicaragua 7
PS - Palestinian Territory 7
PT - Portogallo 7
BA - Bosnia-Erzegovina 6
BG - Bulgaria 6
CH - Svizzera 6
GA - Gabon 6
PA - Panama 6
SY - Repubblica araba siriana 6
CV - Capo Verde 5
GR - Grecia 5
HR - Croazia 5
MD - Moldavia 5
MK - Macedonia 5
PR - Porto Rico 5
RS - Serbia 5
TT - Trinidad e Tobago 5
IS - Islanda 4
KH - Cambogia 4
MN - Mongolia 4
MU - Mauritius 4
Totale 49.262
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Città #
Singapore 3.716
San Jose 2.403
Chandler 1.571
Hong Kong 1.547
Moscow 1.346
Ashburn 1.090
Ho Chi Minh City 915
Jacksonville 833
Beijing 794
Hanoi 731
Santa Clara 539
Princeton 530
Millbury 506
The Dalles 503
Lauterbourg 479
Los Angeles 447
Nanjing 371
Amsterdam 326
Woodbridge 326
Boston 275
Naples 273
Munich 252
Buffalo 244
Wilmington 243
Dallas 225
New York 207
Tokyo 201
Ottawa 190
Hefei 185
São Paulo 179
Houston 166
Haiphong 157
Napoli 148
Nanchang 142
Da Nang 134
Ann Arbor 132
Redondo Beach 131
Turku 116
Frankfurt am Main 102
Shenyang 93
Chicago 89
Des Moines 86
Orem 86
Brooklyn 79
Seattle 79
Tianjin 78
Hebei 77
Council Bluffs 76
Dong Ket 76
Falls Church 76
Boardman 75
Montreal 75
Norwalk 74
Warsaw 73
Chennai 68
Mexico City 66
Kronberg 65
Denver 64
Dublin 62
Biên Hòa 61
Toronto 61
Jiaxing 60
Baghdad 58
Atlanta 57
Nuremberg 57
Rio de Janeiro 57
Johannesburg 56
London 55
Changsha 52
Helsinki 50
Stockholm 49
Belo Horizonte 46
Kunming 46
Cagliari 43
Hải Dương 42
San Francisco 42
Poplar 41
Phoenix 38
Washington 37
Curitiba 34
Rome 34
Manchester 33
Shanghai 33
Aversa 31
Indiana 31
Quito 31
San Mateo 31
Augusta 30
Bangkok 30
Hangzhou 28
Can Tho 26
Charlotte 26
Nairobi 26
Tashkent 26
Amman 25
Guangzhou 25
Lawrence 25
Guarulhos 24
Guayaquil 24
Milan 24
Totale 25.797
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Nome #
A mutated p53 gene alters thyroid cell differentiation 196
The complex CBX7-PRMT1 has a critical role in regulating E-cadherin gene expression and cell migration 184
The Metallophosphoesterase-Domain-Containing Protein 2 (MPPED2) Gene Acts as Tumor Suppressor in Breast Cancer 182
HMGA2 induces pituitary tumorigenesis by enhancing E2F1 activity 179
A ceRNA circuitry involving the long noncoding RNA Klhl14-AS, Pax8 and Bcl2 drives thyroid carcinogenesis 175
PATZ1 acts as a tumor suppressor in thyroid cancer via targeting p53-dependent genes involved in EMT and cell migration 171
HMGA1 silencing reduces stemness and temozolomide resistance in glioblastoma stem cells 171
Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells. 169
HMGA1 induces EZH2 overexpression in human B-cell lymphomas 168
Setting up and exploitation of a nano/technological platform for the evaluation of HMGA1b protein in peripheral blood of cancer patients 167
CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation 167
UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas 166
New somatic mutations and WNK1-B4GALNT3 gene fusion in papillary thyroid carcinoma 163
CBX7 and HMGA1b proteins act in opposite way on the regulation of the SPP1 gene expression 163
NCOA4 inhibits initiation of DNA replication to maintain genome stability 159
HMGA1 protein expression sensitizes cells to cisplatin-induced cell death. 158
UbcH10 expression may be a useful tool in the prognosis of ovarian carcinomas. 158
Identification of the genes up- and down-regulated by the high mobility group A1 (HMGA1) proteins: tissue specificity of the HMGA1-dependent gene regulation. 157
HMGA1 protein overexpression in human breast carcinomas: correlation with ErbB2 expression. 156
Upregulation of miR-21 by Ras in vivo and its role in tumor growth 156
Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes 156
Translational regulation of a novel testis-specific RNF4 transcript. 154
A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor 153
MicroRNAs (miR)-221 and miR-222, both overexpressed in human thyroid papillary carcinomas, regulate p27Kip1 protein levels and cell cycle. 153
The cl2/dro1/ccdc80 null mice develop thyroid and ovarian neoplasias 153
PATZ1 is a target of miR-29b that is induced by Ha-Ras oncogene in rat thyroid cells 153
Thyroid targeting of the N-ras(Gln61Lys) oncogene in transgenic mice results in follicular tumors that progress to poorly differentiated carcinomas. 152
UbcH10 expression in human lymphomas. 152
CBX7 is a tumor suppressor in mice and humans. 152
Phosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytes. 150
The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes 150
The loss of the CBX7 gene expression represents an adverse prognostic marker for survival of colon carcinoma patients. 150
Wnt4 inhibits cell motility induced by oncogenic Ras 150
Role of Dicer1 in thyroid cell proliferation and differentiation 150
Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas. 149
Increased BDNF promoter methylation in the wernicke area of suicide subjects. 148
HMGA1-pseudogene7 transgenic mice develop B cell lymphomas 148
Critical role of CCDC6 in the neoplastic growth of testicular germ cell tumors 147
UbcH10 expression can predict prognosis and sensitivity to the antineoplastic treatment for colorectal cancer patients 147
The Long Non-Coding RNA Prader Willi/Angelman Region RNA5 (PAR5) Is Downregulated in Anaplastic Thyroid Carcinomas Where It Acts as a Tumor Suppressor by Reducing EZH2 Activity 147
Genetic Alterations in differentiated thyroid cancer:what can be expected for gene expression profiling of thyroid carcinomas 146
POZ-, AT-hook-, and Zinc Finger-containing Protein (PATZ) Interacts with Human Oncogene B Cell Lymphoma 6 (BCL6) and Is Required for Its Negative Autoregulation. 146
From protein-protein interaction to E2 inhibitors leads: identification of peptide binding of UbcH10 146
CBX7 modulates the expression of genes critical for cancer progression. 146
High mobility group A1 protein modulates autophagy in cancer cells. 146
Therapy of human pancreatic carcinoma based on suppression of HMGA1 protein synthesis in preclinical models. 144
The Insulin Receptor Substrate (IRS)-1 recruits Phosphatidylinositol 3-Kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret. 144
Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype 144
miR-155 is positively regulated by CBX7 in mouse embryonic fibroblasts and colon carcinomas, and targets the KRAS oncogene 144
Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice 144
Differential Expression of LncRNA in Bladder Cancer Development 143
TACC3 mediates the association of MBD2 with histone acetyltransferases and relieves transcriptional repression of methylated promoters.. 143
Chromatin and DNA methylation dynamics during retinoic acid-induced RET gene transcriptional activation in neuroblastoma cells. 143
Hmga2 is necessary for Otx2-dependent exit of embryonic stem cells from the pluripotent ground state 143
High-mobility group A2 gene expression is frequently induced in non-functioning pituitary adenomas (NFPAs), even in the absence of chromosome 12 polysomy. 142
CDH-16 gene expression in thyroid cell differentiation and transformation. 142
The receptor protein tyrosine phosphatase PTPRJ negatively modulates the CD98hc oncoprotein in lung cancer cells. 142
miR-130b-3p Upregulation Contributes to the Development of Thyroid Adenomas Targeting CCDC6 Gene 141
High-mobility-group A1 (HMGA1) proteins down-regulate the expression of the recombination activating gene 2 (RAG2). 140
IFN-gamma gene expression is controlled by the architectural transcription factor HMGA1. 140
HMGA1-pseudogene expression is induced in human pituitary tumors 140
Characterization of inflammatory infiltrate of ulcerative dermatitis in C57BL/6NCrl-Tg(HMGA1P6)1Pg mice 140
ONYX-015, an E1B gene-defective adenovirus,induces cell death in human anaplastic thyroid carcinoma cell lines. 138
SOM230, a new somatostatin analogue, is highly effective in the therapy of growth hormone/prolactin-secreting pituitary adenomas. 138
Molecular biology of the MEN2 gene 138
Identification of sumoylation sites in CCDC6, the first identified RET partner gene in papillary thyroid carcinoma, uncovers a mode of regulating CCDC6 function on CREB1 transcriptional activity 138
DNA methylation state of the galectin-3 gene represents a potential new marker of thyroid malignancy 138
HMGA2 overexpression plays a critical role in the progression of esophageal squamous carcinoma 138
miR-191 down-regulation plays a role in thyroid follicular tumors through CDK6 targeting. 137
HMGA1 overexpression is associated with a particular subset of human breast carcinomas 137
Glial cell line-derived neurotrophic factor differentially stimulates ret mutants associated with the multiple endocrine neoplasia type 2 syndromes and Hirschsprung's disease 136
The lncRNA RMST is drastically downregulated in anaplastic thyroid carcinomas where exerts a tumor suppressor activity impairing epithelial-mesenchymal transition and stemness 135
Loss of one or two PATZ1 alleles has a critical role in the progression of thyroid carcinomas induced by the RET/PTC1 oncogene 135
HMGA1 protein is a novel target of the ATM kinase. 134
The "next-generation" knowledge of papillary thyroid carcinoma 134
Restoration of CBX7 expression increases the susceptibility of human lung carcinoma cells to irinotecan treatment 133
Hmga1 null mouse embryonic fibroblasts display downregulation of spindle assembly checkpoint gene expression associated to nuclear and karyotypic abnormalities 133
ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases 132
Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice 132
UbcH10 overexpression in human lung carcinomas and its correlation with EGFR and p53 mutational status. 132
UbcH10 is overexpressed in malignant breast carcinomas. 131
Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2). 131
MicroRNA deregulation in human thyroid papillary carcinomas. 130
TRANSCRIPTIONAL PROFILE OF KI-RAS-INDUCED TRANSFORMATION OF THYROID CELLS. 130
FRA-1 protein overexpression is a feature of hyperplastic and neoplastic breast disorders. 130
The RET receptor: function in development and dysfunction in congenital malformation. 130
Transformation of differentiated rat thyroid epithelial cells by viral and cellular oncogenes 130
Critical role of the HMGA2 gene in pituitary adenomas. 130
HMGA1-pseudogene overexpression contributes to cancer progression 130
UBE2C is a transcriptional target of the cell cycle regulator FOXM1 130
Roles of HMGA proteins in cancer. 129
Human papilloma virus 16E7 oncogene does not cooperate with ret/ptc 3 oncogene in the neoplastic transformation of thyroid cells in transgenic mice 129
The different RET-activating capability of mutations of cysteine 620 or cysteine 634 correlates with the multiple endocrine neoplasia type 2 disease phenotype. 129
RET activation and clinicopathologic features in poorly differentiated thyroid tumors. 127
Down-Regulation of the miR-25 and miR-30d Contributes to the Development of Anaplastic Thyroid Carcinoma Targeting the Polycomb Protein EZH2. 126
DNA damage, homology-directed repair, and DNA methylation. 126
Mitogenic and dedifferentiating effect of the K-fgf/hst oncogene on rat thyroid PC clone 3 epithelial cells. 125
Lovastatin enhances the replication of the oncolytic adenovirus dl1520 and its antineoplastic activity against anaplastic thyroid carcinoma cells. 125
Pit-1 upregulation by HMGA proteins has a role in pituitary tumorigenesis. 125
PATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context. 125
Totale 14.534
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Categoria #
all - tutte 165.331
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 165.331
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021407 0 0 0 0 0 0 0 0 0 0 310 97
2021/20222.720 39 0 1 15 24 98 31 89 630 168 514 1.111
2022/20233.440 598 266 70 409 352 409 4 304 545 299 140 44
2023/20242.017 95 314 277 136 88 161 49 228 10 28 429 202
2024/202512.906 781 953 52 81 296 524 1.397 679 1.372 1.334 4.336 1.101
2025/202622.969 2.900 1.615 2.306 2.075 4.104 1.024 2.593 1.331 3.131 1.438 452 0
Totale 49.981