FUSCO, ALFREDO
FUSCO, ALFREDO
DIPARTIMENTO DI MEDICINA MOLECOLARE E BIOTECNOLOGIE MEDICHE
Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2).
2003 Carlomagno, F; Vitagliano, D; Guida, T; Basolo, F; Castellone, Md; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, Massimo
Glial cell line-derived neurotrophic factor induces proliferative inhibition of NT2/D1 cells through RET-mediated up-regulation of the cyclin-dependent kinase inhibitor p27(kip1).
2002 Baldassarre, G; Bruni, P; Boccia, A; Salvatore, G; Melillo, ROSA MARINA; Motti, Ml; Napolitano, M; Belletti, B; Fusco, Alfredo; Santoro, Massimo; Viglietto, G.
Human papilloma virus 16E7 oncogene does not cooperate with ret/ptc 3 oncogene in the neoplastic transformation of thyroid cells in transgenic mice
2000 Portella, Giuseppe; Borselli, C.; Santoro, Massimo; Gerbasio, D.; D'Armiento, M. R.; Dumont, E. J.; Ledent, C.; Rothstein, J. L.; Vecchio, Giancarlo; Fusco, Alfredo
The docking protein FRS2 links RET and its oncogenic forms with the RAS/MAPK cascade.
2001 Melillo, ROSA MARINA; Santoro, Massimo; S. H., Ong; M., Billaud; Fusco, Alfredo; J., Schlessinger; I., Lax
Ret-mediated mitogenesis requires Src kinase activity.
1999 Melillo, ROSA MARINA; Barone, Mv; Lupoli, G; Cirafici, Am; Carlomagno, F; Visconti, R; Matoskova, B; DI FIORE, Pp; Vecchio, G; Fusco, Alfredo; Santoro, Massimo
Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes.
2003 Castellone, Md; Cirafici, Am; DE VITA, G; DE FALCO, V; Malorni, L; Tallini, G; Fagin, Ja; Fusco, Alfredo; Melillo, ROSA MARINA; Santoro, Massimo
Thyroid cell transformation inhibits the expression of a novel protein tyrosinephosphstase.
1997 Zhang, L; Martelli, Ml; Battaglia, C; Trapasso, F; Tramontano, Donatella; Viglietto, G; Porcellini, Antonio; Santoro, M; AND FUSCO, A.
Genetic Alterations in differentiated thyroid cancer:what can be expected for gene expression profiling of thyroid carcinomas
2003 Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, Francesca; Castellone, MARIA DOMENICA; Vitagliano, Donata; Guida, Teresa; Vecchio, Giancarlo; Fusco, Alfredo
Molecular mechanisms of RET activation in human cancer
2002 Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, F; Fusco, Alfredo; Vecchio, Giancarlo
Mitogenic and dedifferentiating effect of the K-fgf/hst oncogene on rat thyroid PC clone 3 epithelial cells.
1993 Battaglia, C; Berlingieri, Mt; Martelli, Ml; Trapasso, F; DELLI BOVI, Pasquale; Fusco, Alfredo
Molecular heterogeneity of RET loss of function in Hirschsprung's disease.
1996 Carlomagno, F; DE VITA, G; Berlingieri, Mt; DE FRANCISCIS, V; Melillo, ROSA MARINA; Colantuoni, V; Kraus, Mh; DI FIORE, Pp; Fusco, Alfredo; M., Santoro
ONYX-015, an E1B gene-defective adenovirus,induces cell death in human anaplastic thyroid carcinoma cell lines.
2002 Portella, Giuseppe; Scala, S.; Vitagliano, Donata; Vecchio, Giancarlo; Fusco, Alfredo
Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels.
2003 Wang, J; Knauf, Ja; Basu, S; Puxeddu, E; Kuroda, H; Santoro, Massimo; Fusco, Alfredo; Fagin, Ja
Tyrosine 1062 of RET-MEN2A mediates activation of Akt(PKB) and MAPK pathways leading to PC12 cell survival.
2000 DE VITA, G; Melillo, ROSA MARINA; Carlomagno, C; Visconti, R; Castellone, Md; Bellacosa, A; Billaud, M; Fusco, Alfredo; Tsichlis, Pn; Santoro, Massimo
The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes
2002 Carlomagno, Francesca; Vitagliano, Donata; Guida, Teresa; Napolitano, M.; Vecchio, Giancarlo; Fusco, Alfredo; Gazit, A.; Levitzki, A.; Santoro, Massimo
The Insulin Receptor Substrate (IRS)-1 recruits Phosphatidylinositol 3-Kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.
2001 Melillo, ROSA MARINA; Carlomagno, Francesca; DE VITA, Gabriella; Formisano, Pietro; Vecchio, Giancarlo; Fusco, Alfredo; Billaud, M.; Santoro, Massimo
The RET receptor: function in development and dysfunction in congenital malformation.
2001 Manie, S; Santoro, Massimo; Fusco, Alfredo; Billaud, M.
RET activation and clinicopathologic features in poorly differentiated thyroid tumors.
2002 Santoro, Massimo; Papotti, M; Chiappetta, G; GARCIA ROSTAN, G; Volante, M; Johnson, C; Camp, Rl; Pentimalli, F; Monaco, C; Herrero, A; Carcangiu, Ml; Fusco, Alfredo
Expression of the RET oncogene induces differentiation of SK-N-BE neuroblastoma cells.
1995 D'Alessio, A; DE VITA, Gabriella; Cal, G; Nitsch, Lucio; Fusco, Alfredo; Vecchio, G; Santelli, G; Santoro, M; DE FRANCISCIS, V.
MicroRNA deregulation in human thyroid papillary carcinomas.
2006 Pallante, Pierlorenzo; Visone, R; Ferracin, M; Ferraro, A; Berlingieri, Mt; Troncone, Giancarlo; Chiappetta, G; Liu, Cg; Santoro, Massimo; Negrini, M; Croce, Cm; Fusco, Alfredo
Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
---|---|---|---|---|
Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2). | 1.1 Articolo in rivista | 2003 | Carlomagno, F; Vitagliano, D; Guida, T; Basolo, F; Castellone, Md; Melillo, ROSA MARINA; Fusco, Alfredo; Santoro, Massimo | |
Glial cell line-derived neurotrophic factor induces proliferative inhibition of NT2/D1 cells through RET-mediated up-regulation of the cyclin-dependent kinase inhibitor p27(kip1). | 1.1 Articolo in rivista | 2002 | Baldassarre, G; Bruni, P; Boccia, A; Salvatore, G; Melillo, ROSA MARINA; Motti, Ml; Napolitano, M; Belletti, B; Fusco, Alfredo; Santoro, Massimo; Viglietto, G. | |
Human papilloma virus 16E7 oncogene does not cooperate with ret/ptc 3 oncogene in the neoplastic transformation of thyroid cells in transgenic mice | 1.1 Articolo in rivista | 2000 | Portella, Giuseppe; Borselli, C.; Santoro, Massimo; Gerbasio, D.; D'Armiento, M. R.; Dumont, E. J.; Ledent, C.; Rothstein, J. L.; Vecchio, Giancarlo; Fusco, Alfredo | |
The docking protein FRS2 links RET and its oncogenic forms with the RAS/MAPK cascade. | 1.1 Articolo in rivista | 2001 | Melillo, ROSA MARINA; Santoro, Massimo; S. H., Ong; M., Billaud; Fusco, Alfredo; J., Schlessinger; I., Lax | |
Ret-mediated mitogenesis requires Src kinase activity. | 1.1 Articolo in rivista | 1999 | Melillo, ROSA MARINA; Barone, Mv; Lupoli, G; Cirafici, Am; Carlomagno, F; Visconti, R; Matoskova, B; DI FIORE, Pp; Vecchio, G; Fusco, Alfredo; Santoro, Massimo | |
Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes. | 1.1 Articolo in rivista | 2003 | Castellone, Md; Cirafici, Am; DE VITA, G; DE FALCO, V; Malorni, L; Tallini, G; Fagin, Ja; Fusco, Alfredo; Melillo, ROSA MARINA; Santoro, Massimo | |
Thyroid cell transformation inhibits the expression of a novel protein tyrosinephosphstase. | 1.1 Articolo in rivista | 1997 | Zhang, L; Martelli, Ml; Battaglia, C; Trapasso, F; Tramontano, Donatella; Viglietto, G; Porcellini, Antonio; Santoro, M; AND FUSCO, A. | |
Genetic Alterations in differentiated thyroid cancer:what can be expected for gene expression profiling of thyroid carcinomas | 1.1 Articolo in rivista | 2003 | Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, Francesca; Castellone, MARIA DOMENICA; Vitagliano, Donata; Guida, Teresa; Vecchio, Giancarlo; Fusco, Alfredo | |
Molecular mechanisms of RET activation in human cancer | 2.1 Contributo in volume (Capitolo o Saggio) | 2002 | Santoro, Massimo; Melillo, ROSA MARINA; Carlomagno, F; Fusco, Alfredo; Vecchio, Giancarlo | |
Mitogenic and dedifferentiating effect of the K-fgf/hst oncogene on rat thyroid PC clone 3 epithelial cells. | 1.1 Articolo in rivista | 1993 | Battaglia, C; Berlingieri, Mt; Martelli, Ml; Trapasso, F; DELLI BOVI, Pasquale; Fusco, Alfredo | |
Molecular heterogeneity of RET loss of function in Hirschsprung's disease. | 1.1 Articolo in rivista | 1996 | Carlomagno, F; DE VITA, G; Berlingieri, Mt; DE FRANCISCIS, V; Melillo, ROSA MARINA; Colantuoni, V; Kraus, Mh; DI FIORE, Pp; Fusco, Alfredo; M., Santoro | |
ONYX-015, an E1B gene-defective adenovirus,induces cell death in human anaplastic thyroid carcinoma cell lines. | 1.1 Articolo in rivista | 2002 | Portella, Giuseppe; Scala, S.; Vitagliano, Donata; Vecchio, Giancarlo; Fusco, Alfredo | |
Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels. | 1.1 Articolo in rivista | 2003 | Wang, J; Knauf, Ja; Basu, S; Puxeddu, E; Kuroda, H; Santoro, Massimo; Fusco, Alfredo; Fagin, Ja | |
Tyrosine 1062 of RET-MEN2A mediates activation of Akt(PKB) and MAPK pathways leading to PC12 cell survival. | 1.1 Articolo in rivista | 2000 | DE VITA, G; Melillo, ROSA MARINA; Carlomagno, C; Visconti, R; Castellone, Md; Bellacosa, A; Billaud, M; Fusco, Alfredo; Tsichlis, Pn; Santoro, Massimo | |
The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes | 1.1 Articolo in rivista | 2002 | Carlomagno, Francesca; Vitagliano, Donata; Guida, Teresa; Napolitano, M.; Vecchio, Giancarlo; Fusco, Alfredo; Gazit, A.; Levitzki, A.; Santoro, Massimo | |
The Insulin Receptor Substrate (IRS)-1 recruits Phosphatidylinositol 3-Kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret. | 1.1 Articolo in rivista | 2001 | Melillo, ROSA MARINA; Carlomagno, Francesca; DE VITA, Gabriella; Formisano, Pietro; Vecchio, Giancarlo; Fusco, Alfredo; Billaud, M.; Santoro, Massimo | |
The RET receptor: function in development and dysfunction in congenital malformation. | 1.1 Articolo in rivista | 2001 | Manie, S; Santoro, Massimo; Fusco, Alfredo; Billaud, M. | |
RET activation and clinicopathologic features in poorly differentiated thyroid tumors. | 1.1 Articolo in rivista | 2002 | Santoro, Massimo; Papotti, M; Chiappetta, G; GARCIA ROSTAN, G; Volante, M; Johnson, C; Camp, Rl; Pentimalli, F; Monaco, C; Herrero, A; Carcangiu, Ml; Fusco, Alfredo | |
Expression of the RET oncogene induces differentiation of SK-N-BE neuroblastoma cells. | 1.1 Articolo in rivista | 1995 | D'Alessio, A; DE VITA, Gabriella; Cal, G; Nitsch, Lucio; Fusco, Alfredo; Vecchio, G; Santelli, G; Santoro, M; DE FRANCISCIS, V. | |
MicroRNA deregulation in human thyroid papillary carcinomas. | 1.1 Articolo in rivista | 2006 | Pallante, Pierlorenzo; Visone, R; Ferracin, M; Ferraro, A; Berlingieri, Mt; Troncone, Giancarlo; Chiappetta, G; Liu, Cg; Santoro, Massimo; Negrini, M; Croce, Cm; Fusco, Alfredo |