IRIS
MICELI, Francesco
 Distribuzione geografica
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Continente #
AS - Asia 2.526
NA - Nord America 1.857
EU - Europa 1.681
SA - Sud America 378
AF - Africa 52
Continente sconosciuto - Info sul continente non disponibili 1
Totale 6.495
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Nazione #
US - Stati Uniti d'America 1.762
SG - Singapore 1.039
RU - Federazione Russa 673
VN - Vietnam 563
IT - Italia 515
CN - Cina 419
BR - Brasile 312
HK - Hong Kong 214
NL - Olanda 94
FR - Francia 80
DE - Germania 74
JP - Giappone 53
BD - Bangladesh 51
IN - India 47
CA - Canada 44
FI - Finlandia 44
GB - Regno Unito 39
UA - Ucraina 35
IE - Irlanda 34
AR - Argentina 27
SE - Svezia 26
MX - Messico 22
KR - Corea 21
ID - Indonesia 20
IQ - Iraq 15
ZA - Sudafrica 14
AT - Austria 12
PL - Polonia 11
TH - Thailandia 11
EC - Ecuador 10
PH - Filippine 10
ES - Italia 9
BE - Belgio 8
UZ - Uzbekistan 8
EG - Egitto 7
SA - Arabia Saudita 7
TR - Turchia 7
TW - Taiwan 7
VE - Venezuela 7
CL - Cile 6
CO - Colombia 6
PY - Paraguay 6
PK - Pakistan 5
GR - Grecia 4
IL - Israele 4
JM - Giamaica 4
LT - Lituania 4
AE - Emirati Arabi Uniti 3
AO - Angola 3
BB - Barbados 3
BZ - Belize 3
CR - Costa Rica 3
DZ - Algeria 3
ET - Etiopia 3
GH - Ghana 3
JO - Giordania 3
KE - Kenya 3
LB - Libano 3
NI - Nicaragua 3
RS - Serbia 3
TN - Tunisia 3
CG - Congo 2
CH - Svizzera 2
DO - Repubblica Dominicana 2
GE - Georgia 2
GT - Guatemala 2
HU - Ungheria 2
IS - Islanda 2
KG - Kirghizistan 2
MA - Marocco 2
MY - Malesia 2
NG - Nigeria 2
OM - Oman 2
PR - Porto Rico 2
PT - Portogallo 2
UY - Uruguay 2
ZW - Zimbabwe 2
AG - Antigua e Barbuda 1
AL - Albania 1
AZ - Azerbaigian 1
BG - Bulgaria 1
BS - Bahamas 1
BW - Botswana 1
CW - ???statistics.table.value.countryCode.CW??? 1
CY - Cipro 1
DK - Danimarca 1
DM - Dominica 1
GM - Gambi 1
GY - Guiana 1
HR - Croazia 1
HT - Haiti 1
KN - Saint Kitts e Nevis 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
LK - Sri Lanka 1
LV - Lettonia 1
MD - Moldavia 1
ML - Mali 1
MU - Mauritius 1
MW - Malawi 1
Totale 6.487
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Città #
Singapore 486
San Jose 249
Hong Kong 201
Chandler 168
Moscow 165
Ho Chi Minh City 149
Beijing 142
Naples 114
Ashburn 113
Hanoi 104
Hefei 83
Dong Ket 80
Millbury 68
The Dalles 64
Santa Clara 60
Amsterdam 58
Los Angeles 58
Lauterbourg 53
Napoli 40
Tokyo 40
Dallas 39
Princeton 37
Marano di Napoli 35
New York 31
Jacksonville 30
São Paulo 30
Des Moines 28
Haiphong 28
Buffalo 27
Ottawa 24
Orem 22
Formia 20
Redondo Beach 20
Boston 18
Da Nang 17
Guangzhou 17
Breda 16
Council Bluffs 16
Nuremberg 16
Trentola-Ducenta 16
Nanjing 15
Seoul 15
Wilmington 15
Lawrence 14
Chicago 13
Biên Hòa 12
Milan 12
Norwalk 12
Brasília 10
Denver 10
Houston 10
Johannesburg 10
Brooklyn 9
Chennai 9
Frankfurt am Main 9
Mexico City 9
Mumbai 9
Munich 9
Seattle 9
Hebei 8
Jakarta 8
Rome 8
Warsaw 8
Ann Arbor 7
Atlanta 7
Belo Horizonte 7
Bắc Ninh 7
Hải Dương 7
Manchester 7
Rio de Janeiro 7
Stockholm 7
Tashkent 7
Turin 7
Verona 7
Baghdad 6
Giugliano in Campania 6
Helsinki 6
Kyoto 6
Montreal 6
Shenyang 6
Bhopal 5
Boardman 5
Charlotte 5
Curitiba 5
Fortaleza 5
Lappeenranta 5
London 5
Nanchang 5
Palermo 5
Pescara 5
Pisa 5
Poplar 5
Pozzuoli 5
Quito 5
Redwood City 5
Thái Nguyên 5
Bangkok 4
Barano d'Ischia 4
Dublin 4
Fairfield 4
Totale 3.434
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Nome #
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 196
A novel hyperekplexia-causing mutation in the pre-trasmembrane segm 1 of the human glycine receptor alpha 1 subunit reduces membrane expression and impairs gating by agonists 183
Kv7 channel activation reduces brain endothelial cell permeability and prevents kainic acid-induced blood-brain barrier damage 179
Decreased subunit stability as a novel mechanism for potassium current impairment by a KCNQ2 C terminus mutation causing benign familial neonatal convulsions 158
Involvement of KCNQ2 subunits in [3H]dopamine release triggered by depolarization and pre-synaptic muscarinic receptor activation from rat striatal synaptosomes. 152
Insights into the pathogenesis of ATP1A1-related CMT disease using patient-specific iPSCs 147
A novel KCNQ3 mutation in familial epilepsy with focal seizures and intellectual disability 145
The voltage-sensing domain of Kv7.2 channels as a molecular target for epilepsy-causing mutations and anticonvulsants 142
Decreased Subunit Stability as a Novel Mechanismfor PotassiumCurrent Impairment by a KCNQ2 C Terminus Mutation Causing Benign Familial Neonatal Convulsions 141
A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy 138
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits 138
Driving with no brakes: Molecular pathophysiology of Kv7 potassium channels 137
Autism and developmental disability caused by KCNQ3 gain-of-function variants 137
Generation of an iPSC line (UNINAi001-A) from a girl with neonatal-onset epilepsy and non-syndromic intellectual disability carrying the homozygous KCNQ3 p.PHE534ILEfs*15 variant and of an iPSC line (UNINAi002-A) from a non-carrier, unaffected brother 136
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 133
Genotype-phenotype correlations in patients with de novo KCNQ2 pathogenic variants 133
Neuronal potassium channel openers in the management of epilepsy: Role and potential of retigabine 131
GAIN-OF-FUNCTION DUE TO INCREASED OPENING PROBABILITY BY TWO KCNQ5 PORE VARIANTS CAUSING DEVELOPMENTAL AND/OR EPILEPTIC ENCEPHALOPATHY 129
Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels 127
Atypical gating of M-type potassium channels conferred by mutations in uncharged residues in the S4 region of KCNQ2 causing benign familial neonatal convulsions. 123
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism 122
Specification of skeletal muscle differentiation by repressor element-1 silencing transcription factor (REST)-regulated Kv7.4 potassium channels 119
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction 119
Potassium current inactivation as a novel pathomechanism for KCNQ2 developmental and epileptic encephalopathy 118
Atypical gating of M-type potassium channels conferred by mutations in uncharged residues in the S4 region of KCNQ2 causing benign familial neonatal convulsions 115
Gating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain 115
Human neoplastic mesothelial cells express voltage-gated sodium channels involved in cell motility 113
Vasorelaxation by hydrogen sulphide involves activation of Kv7 potassium channels 113
Coupling between the voltage-sensing and phosphatase domains of Ci-VSP 113
Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7.2 potassium channel subunits 112
Functional analysis of novel KCNQ2 and KCNQ3 gene variants found in a large pedigree with benign familial neonatal convulsions (BFNC) 109
Early treatment with quinidine in two patients with epilepsy of infancy with migrating focal seizures (EIMFS) due to gain-of-function KCNT1 mutations: functional studies, clinical responses and critical issues for personalized therapy 107
Pharmacological Targeting Of Neuronal Kv7.2/3 Channels: A Focus On Chemotypes And Receptor Sites 103
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 101
A Novel Kv7.3 Variant in the Voltage-Sensing S4 Segment in a Family With Benign Neonatal Epilepsy: Functional Characterization and in vitro Rescue by β-Hydroxybutyrate 101
Gating consequences of charge neutralization of arginine residues in the S4 segment of K(v)7.2, an epilepsy-linked K+ channel subunit 100
IKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunits 99
Distinct epilepsy phenotypes and response to drugs in KCNA1 gain- and loss-of function variants 98
Gating currents from neuronal KV7.4 Channels: General features and correlation with the ionic conductance 96
Kv7.4 channels regulate potassium permeability in neuronal mitochondria 93
Subtype-selective activation of K(v)7 channels by AaTXKβ₂₋₆₄, a novel toxin variant from the Androctonus australis scorpion venom. 92
Constitutive opening of the Kv7.2 pore activation gate causes KCNQ2-developmental encephalopathy 88
Activation of Kv7 potassium channels inhibits intracellular Ca2+ increases triggered by TRPV1-mediated pain-inducing stimuli in F11 immortalized sensory neurons 87
Phenotypic and functional assessment of two novel KCNQ2 gain-of-function variants Y141N and G239S and effects of amitriptyline treatment 82
A new K+channel-independent mechanism is involved in the antioxidant effect of XE-991 in an in vitro model of glucose metabolism impairment: implications for Alzheimer's disease 82
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 82
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP2-Dependent K+ Channel Gating 82
Personalized stem cell therapy to correct corneal defects due to a unique homozygous-heterozygous mosaicism of ectrodactyly-ectodermal dysplasia-clefting syndrome 78
Cardiotoxic effects of antihistamines: From basics to clinics (...and back) 77
Expression and function of Kv7.4 channels in rat cardiac mitochondria: Possible targets for cardioprotection 76
Correlating the Clinical and Genetic Features of Benign Familial Neonatal Seizures (BFNS) with the Functional Consequences of Underlying Mutations 74
Epileptic encephalopathy in a patientwith a novel variant in the Kv7.2 S2 transmembrane segment: Clinical, genetic, and functional features 72
In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel 69
Hyperekplexia caused by dominant-negative suppression of GLYRA1 function 68
Novel KCNQ2 and KCNQ3 mutations in a large cohort of families with benign neonatal epilepsy: First evidence for an altered channel regulation by syntaxin-1A 68
Neutralization of a unique, negatively-charged residue in the voltage sensor of KV7.2 subunits in a sporadic case of benign familial neonatal seizures 68
Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain-of-function variant 65
The fast-dissociating D2 antagonist antipsychotic JNJ-37822681 is a neuronal Kv7 channel opener: Potential repurposing for epilepsy treatment 61
Molecular pharmacology and therapeutic potential of neuronal Kv7-modulating drugs 59
The Role of Kv7.2 in Neurodevelopment: Insights and Gaps in Our Understanding 49
Editorial: Kv7 Channels: Structure, Physiology, and Pharmacology 48
Two-step voltage-sensor activation of the human KV7.4 channel and effect of a deafness-associated mutation 9
Totale 6.607
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Categoria #
all - tutte 21.052
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.052
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022310 10 2 1 5 8 4 4 17 40 16 86 117
2022/2023543 56 53 6 111 76 46 6 30 81 58 16 4
2023/2024218 13 30 38 11 14 14 3 14 11 7 37 26
2024/20251.589 68 70 9 15 43 69 217 108 146 160 524 160
2025/20263.253 319 269 423 303 490 150 352 213 396 176 97 65
2026/202766 66 0 0 0 0 0 0 0 0 0 0 0
Totale 6.607