IRIS
PALADINO, SIMONA
 Distribuzione geografica
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Continente #
NA - Nord America 1.663
EU - Europa 1.417
AS - Asia 792
AF - Africa 47
Continente sconosciuto - Info sul continente non disponibili 1
OC - Oceania 1
SA - Sud America 1
Totale 3.922
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Nazione #
US - Stati Uniti d'America 1.635
IT - Italia 969
SG - Singapore 332
CN - Cina 231
HK - Hong Kong 187
NL - Olanda 119
IE - Irlanda 62
FI - Finlandia 61
DE - Germania 57
CI - Costa d'Avorio 42
GB - Regno Unito 40
UA - Ucraina 34
CA - Canada 27
IN - India 21
FR - Francia 18
SE - Svezia 18
VN - Vietnam 13
RU - Federazione Russa 12
ES - Italia 7
CZ - Repubblica Ceca 6
RS - Serbia 5
ZA - Sudafrica 4
DK - Danimarca 3
IR - Iran 3
TW - Taiwan 3
AT - Austria 2
AU - Australia 1
BA - Bosnia-Erzegovina 1
BE - Belgio 1
BG - Bulgaria 1
CL - Cile 1
EU - Europa 1
MX - Messico 1
PK - Pakistan 1
PL - Polonia 1
SD - Sudan 1
TR - Turchia 1
Totale 3.922
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Città #
Chandler 308
Singapore 273
Hong Kong 187
Napoli 172
Naples 167
Santa Clara 119
Amsterdam 102
Ashburn 92
Millbury 83
Jacksonville 61
Princeton 58
Nanjing 57
Boston 50
Beijing 37
Des Moines 35
Wilmington 27
Lawrence 24
Nanchang 23
Rome 23
Salerno 21
Milan 20
Ottawa 19
Formia 17
Woodbridge 16
Houston 15
Seattle 15
Pozzuoli 13
Shanghai 13
Acerra 12
Dong Ket 12
Hebei 12
Ann Arbor 11
Caserta 11
Redwood City 11
Tianjin 11
Changsha 10
Los Angeles 10
Shenyang 8
Dublin 7
Falls Church 7
Jiaxing 7
Kronberg 7
Kunming 7
Munich 7
Pune 7
Racale 7
Bacoli 6
Barano d'Ischia 6
Caivano 6
Moscow 6
Norwalk 6
Portici 6
San Mateo 6
Toronto 6
Aversa 5
Boardman 5
Casoria 5
London 5
Washington 5
Avellino 4
Belgrade 4
Felitto 4
Florence 4
Fort Worth 4
Helsinki 4
Limatola 4
Monte di Procida 4
Parma 4
Altamura 3
Augusta 3
Boscoreale 3
Brno 3
Cambridge 3
Campagna 3
Casalnuovo Di Napoli 3
Contursi 3
Copenhagen 3
Fairfield 3
Fisciano 3
Gainesville 3
Guangzhou 3
Indiana 3
Lanzhou 3
Lappeenranta 3
Limbiate 3
Marano di Napoli 3
Minturno 3
Montesarchio 3
New York 3
Palermo 3
Paris 3
Sassari 3
Springs 3
Stockport 3
Taizhou 3
Valladolid 3
Zhengzhou 3
Airola 2
Ardabil 2
Battipaglia 2
Totale 2.413
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Nome #
Alteration of endosomal trafficking is associated with early-onset parkinsonism caused by SYNJ1 mutations 125
Novel mutations in dystonin provide clues to the pathomechanisms of HSAN-VI 102
Alteration of endosomal trafficking is associated with neurodegenerative diseases 94
Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer 85
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 82
Metformin restores the mitochondrial network and reverses mitochondrial dysfunction in Down syndrome cells 82
PD-1 blockade delays tumor growth by inhibiting an intrinsic SHP2/Ras/MAPK signalling in thyroid cancer cells. 79
Convergent effects of resveratrol and PYK2 on prostate cells 75
Deregulation of microtubule organization and RNA metabolism in Arx models for Lissencephaly and developmental epileptic encephalopathy 75
EGFR activation triggers cellular hypertrophy and lysosomal disease in NAGLU-depleted cardiomyoblasts, mimicking the hallmarks of mucopolysaccharidosis IIIB 72
Wilson disease protein ATP7B utilizes lysosomal exocytosis to maintain copper homeostasis 71
High mobility group A1 protein modulates autophagy in cancer cells. 70
The thyroid hormone activating enzyme, type 2 deiodinase, induces myogenic differentiation by regulating mitochondrial metabolism and reducing oxidative stress 68
Probing the Eumelanin-Silica Interface in Chemically Engineered Bulk Hybrid Nanoparticles for Targeted Subcellular Antioxidant Protection 64
La cellula come una grande Fabbrica 63
Regulation of sub-compartmental targeting and folding properties of the Prion-like protein Shadoo 62
Mitochondrial dysfunction in down syndrome: molecular mechanisms and therapeutic targets 61
Characterization of the properties and trafficking of an anchorless form of the prion protein. 60
PERK-mediated unfolded protein response activation and oxidative stress in PARK20 fibroblasts 60
Effects of long-term citrate treatment in the PC3 prostate cancer cell line 60
Regulation of trafficking and folding of cellular prion protein PrPC and its shadow Shadoo 59
A constitutively active Rac impairs the acquisition of epithelial cell polarity. 56
Targeting mitochondrial network architecture in down syndrome and aging 52
Fighting the Huntington’s Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization, In Vitro and In Vivo Studies 51
ZSCAN4+ mouse embryonic stem cells have an oxidative and flexible metabolic profile 50
Human trisomic ipscs from down syndrome fibroblasts manifest mitochondrial alterations early during neuronal differentiation 50
Molecular determinants of ER-Golgi contacts identified through a new FRET-FLIM system 48
Targeting Heparan Sulfate Proteoglycans as a Novel Therapeutic Strategy for Mucopolysaccharidoses 47
The combined effect of USP7 inhibitors and PARP inhibitors in hormone-sensitive and castration-resistant prostate cancer cells 47
Nrf2 pathway in age-related neurological disorders: Insights into MicroRNAs 47
Oligomerization is a specific requirement for apical sorting of GPI-anchored proteins but not for non-raft associated apical proteins 46
Detergent-resistant membrane domains but not the proteasome are involved in the misfolding of a PrP mutant retained in the endoplasmic reticulum. 45
Caveolin and caveolae are not directly involved in GPI-anchored proteins sorting 45
Phenotypic effects of homeodomain-interacting protein kinase 2 deletion in mice 45
Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1. 44
Pioglitazone improves mitochondrial organization and bioenergetics in down syndrome cells 44
Localization of neuroglobin in the brain of R6/2 mouse model of Huntington's disease 43
Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway 43
Membrane association of Rac and E-cadherin in FRT thyroid epithelial cells. 42
PrP(C) association with lipid rafts in the early secretory pathway stabilizes its cellular conformation. 42
Detergent-resistant membrane microdomains and apical sorting of GPI-anchored proteins in polarized epithelial cells. 41
Trafficking and Membrane Organization of GPI-Anchored Proteins in Health and Diseases 40
PrPC is sorted to the basolateral membrane of epithelial cells independently of its association with rafts. 39
Truncated Analogues of a G-Quadruplex-Forming Aptamer Targeting Mutant Huntingtin: Shorter Is Better! 38
TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins. 38
Cell-penetrating peptides: two faces of the same coin 38
Calcium levels in the Golgi complex regulate clustering and apical sorting of GPI-APs in polarized epithelial cells 38
Protein oligomerization modulates raft partitioning and apical sorting of GPI-anchored proteins. 37
Lipid rafts and clathrin cooperate in the internalization of PrP in epithelial FRT cells. 37
Endoplasmic reticulum stress reduces the export from the ER and alters the architecture of post-ER compartments 37
Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice 37
Identification of sumoylation sites in CCDC6, the first identified RET partner gene in papillary thyroid carcinoma, uncovers a mode of regulating CCDC6 function on CREB1 transcriptional activity 36
Resveratrol Couples Apoptosis with Autophagy in UVB-Irradiated HaCaT Cells 36
Analysis of detergent-resistant membranes associated with apical and basolateral GPI-anchored proteins in polarized epithelial cells. 34
Lipid rafts and sorting of GPI-anchored proteins 34
Analysis of TrkA and p75NTR cellular localization and signalling capability after NGF stimulation 34
Verapamil Inhibits Ser202/Thr205 Phosphorylation of Tau by Blocking TXNIP/ROS/p38 MAPK Pathway 34
Editorial: Novel Mechanism of Radioactive Iodine Refractivity in Thyroid Cancer 34
GPI-Anchored proteins are confined in subdiffraction clusters at the apical surface of polarized epithelial cells 34
Analysis of mechanisms of sorting of GPI-anchored proteins in polarized epithelial cells: role of the GPI-anchor and ectodomain 33
Overexpression of the Hsa21 Transcription Factor RUNX1 Modulates the Extracellular Matrix in Trisomy 21 Cells 32
Mechanism of sorting of GPI-anchored proteins in polarized epithelial cells 32
Caveolin transfection results in caveolae formation but not apical sorting of glycosylphosphatidylinositol (GPI)-anchored proteins in epithelial cells. 31
Chronic exposure to l-BMAA cyanotoxin induces cytoplasmic TDP-43 accumulation and glial activation, reproducing an amyotrophic lateral sclerosis-like phenotype in mice 30
Different GPI-attachment signals affect the oligomerisation of GPI-anchored proteins and their apical sorting. 30
N- and O- glycans are not directly involved in the oligomerization and apical sorting of GPI proteins. 30
Study of mechanisms of protein delivery in polarized epithelial cells by live microscopy. 30
New therapeutic perspectives in CCDC6 deficient lung cancer cells. 30
Clustering in the Golgi apparatus governs sorting and function of GPI-APs in polarized epithelial cells 30
Role of rafts and caveolins in the sorting and segnalling of growth factor receptor involved in thyroid cancer. 29
Down Syndrome Fetal Fibroblasts Display Alterations of Endosomal Trafficking Possibly due to SYNJ1 Overexpression 28
Role of rafts and caveolins in the sorting and signalling of growth factor receptor involved in thyroid cancer. 28
Sorting of GPI-anchored proteins in living epithelial cells 28
Genetics and Molecular Basis of Congenital Heart Defects in Down Syndrome: Role of Extracellular Matrix Regulation 27
The Shp-1 and Shp-2, tyrosine phosphatases, are recruited on cell membrane in two distinct molecular complexes including Ret oncogenes. 27
Differential recognition of a tyrosine-dependent signal in the basolateral and endocytic pathways of thyroid epithelial cells. 27
Anandamide inhibits the Wnt/β-catenin signalling pathway in human breast cancer MDA MB 231 cells 27
Genotype-Phenotype Correlations in Neurofibromatosis Type 1: Identification of Novel and Recurrent NF1 Gene Variants and Correlations with Neurocognitive Phenotype 26
HIPK2 in cancer biology and therapy: Recent findings and future perspectives 26
Organization of GPI-anchored proteins at the cell surface and its physiopathological relevance 26
Meldonium improves Huntington’s disease mitochondrial dysfunction by restoring peroxisome proliferator-activated receptor γ coactivator 1α expression 26
Polarized sorting of GPI proteins 26
Role of rafts and caveolins in the sorting and signalling of growth factor receptor involved in thyroid cancer. 25
Selective roles for cholesterol and actin in compartmentalization of different proteins in the Golgi and plasma membrane of polarized cells. 25
Plasma membrane organization of GPI-anchored proteins 25
PrPC is sorted to the basolateral domain of epithelial cells independently of its association with rafts. 25
Imaging techniques to study protein sorting in polarized epithelial cells 24
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK 23
Role of rafts and caveolins in the sorting and signaling of growth factor receptor involved in thyroid cancer 23
N6-isopentenyladenosine improves nuclear shape in fibroblasts from humans with progeroid syndromes by inhibiting the farnesylation of prelamin A. 22
In vivo localization of GPI-anchored proteins in epithelial cells. 21
Expanding SPG18 clinical spectrum: autosomal dominant mutation causes complicated hereditary spastic paraplegia in a large family 20
A y(+)LAT-1 mutant protein interferes with y(+)LAT-2 activity: implications for the molecular pathogenesis of lysinuric protein intolerance. 19
N-Glycosylation instead of cholesterol mediates oligomerization and apical sorting of GPI-APs in FRT cells. 17
FBXW7 and USP7 regulate CCDC6 turnover during the cell cycle and affect cancer drugs susceptibility in NSCLC 17
Functional interaction between p75NTR and TrkA: the endocytic trafficking of p75NTR is driven by TrkA and regulates TrkA-mediated signalling. 16
GPI-anchored proteins are directly targeted to the apical surface in fully polarized MDCK cells. 15
Bone marrow mesenchymal stem cells as a possible ruxolitinib reservoir in the bone marrow niche 13
HIPK2 in the physiology of nervous system and its implications in neurological disorders 12
Golgi sorting regulates organization and activity of GPI proteins at apical membranes 11
Totale 4.164
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Categoria #
all - tutte 17.685
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.685
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020103 0 0 0 0 0 0 7 4 11 25 30 26
2020/2021310 9 18 34 16 31 41 17 46 33 5 35 25
2021/2022600 16 16 4 23 21 24 11 26 69 64 114 212
2022/2023840 96 78 35 59 89 73 19 89 121 110 52 19
2023/2024634 27 95 102 45 31 65 23 64 27 24 90 41
2024/2025864 154 155 27 39 103 176 210 0 0 0 0 0
Totale 4.181