IRIS
NICOSIA, Alfredo
 Distribuzione geografica
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Continente #
NA - Nord America 2.010
EU - Europa 799
AS - Asia 752
AF - Africa 31
Continente sconosciuto - Info sul continente non disponibili 1
OC - Oceania 1
SA - Sud America 1
Totale 3.595
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Nazione #
US - Stati Uniti d'America 1.925
SG - Singapore 396
CN - Cina 332
IT - Italia 257
IE - Irlanda 167
FI - Finlandia 126
NL - Olanda 123
CA - Canada 85
GB - Regno Unito 55
CI - Costa d'Avorio 29
DE - Germania 22
SE - Svezia 17
IN - India 12
RO - Romania 11
FR - Francia 7
BE - Belgio 4
HK - Hong Kong 4
RU - Federazione Russa 3
ES - Italia 2
GH - Ghana 2
KR - Corea 2
PK - Pakistan 2
AU - Australia 1
BO - Bolivia 1
EU - Europa 1
LU - Lussemburgo 1
MO - Macao, regione amministrativa speciale della Cina 1
PL - Polonia 1
PT - Portogallo 1
RS - Serbia 1
TH - Thailandia 1
TR - Turchia 1
UA - Ucraina 1
UZ - Uzbekistan 1
Totale 3.595
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Città #
Chandler 461
Singapore 311
Millbury 149
Amsterdam 122
Nanjing 120
Princeton 113
Ashburn 92
Boston 92
Naples 92
Ottawa 82
Santa Clara 79
Des Moines 62
Lawrence 51
Wilmington 46
Beijing 45
Napoli 32
Hebei 31
Nanchang 30
Shenyang 27
Dearborn 20
Jiaxing 20
Tianjin 17
Falls Church 15
Milan 14
Changsha 13
Norwalk 12
Helsinki 10
Pune 10
New York 9
The Dalles 8
Washington 8
Marano 7
Los Angeles 6
Munich 6
Seattle 6
Bologna 5
Frankfurt am Main 5
Brussels 4
Chicago 4
Fairfield 4
Formia 4
Fort Worth 4
Hong Kong 4
Kronberg 4
Lappeenranta 4
London 4
Marano di Napoli 4
Rome 4
Indiana 3
Kunming 3
Redmond 3
Salerno 3
San Vitaliano 3
Simi Valley 3
Toronto 3
Accra 2
Ann Arbor 2
Boardman 2
Casavatore 2
Casoria 2
Edinburgh 2
Ischia 2
Lanzhou 2
Molfetta 2
Nuremberg 2
Paris 2
Redwood City 2
San Francisco 2
Shanghai 2
Springfield 2
Stockholm 2
Woodbridge 2
Acerra 1
Afragola 1
Aprilia 1
Augusta 1
Belgrade 1
Birmingham 1
Bucharest 1
Caserta 1
Catanzaro 1
Chungnam 1
City of London 1
Cochabamba 1
Coimbatore 1
Dezhou 1
Dublin 1
Ferrara 1
Fisciano 1
Fremont 1
Galati 1
Gdansk 1
Glasgow 1
Gondomar 1
Guangzhou 1
Gunzenhausen 1
Hangzhou 1
Hefei 1
Horia 1
Jinan 1
Totale 2.355
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Nome #
Integrity of the antiviral STING-mediated DNA sensing in tumor cells is required to sustain the immunotherapeutic efficacy of herpes simplex oncolytic virus 75
Generation of a novel mesothelin-targeted oncolytic herpes virus and implemented strategies for manufacturing 68
Novel human anti-Claudin 1 monoclonal antibodies inhibit HCV infection and may synergize with anti-SRB1 mAb. 55
Generation of a retargeted oncolytic herpes virus encoding adenosine deaminase for tumor adenosine clearance 47
Rapid Affinity Maturation of Novel Anti-PD-L1 Antibodies by a Fast Drop of the Antigen Concentration and FACS Selection of Yeast Libraries 45
A genetic vaccine encoding shared cancer neoantigens to treat tumors with microsatellite instability 45
One-Step Recovery of scFv Clones from High-Throughput Sequencing-Based Screening of Phage Display Libraries Challenged to Cells Expressing Native Claudin-1 43
Massive parallel screening of phage libraries for the generation of repertoires of human immunomodulatory monoclonal antibodies. 43
Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge 42
A long non-coding SINEUP RNA boosts semi-stable production of fully human monoclonal antibodies in HEK293E cells 42
Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling 42
A Bipartite Activation Domain Is Responsible For the Activity of Transcription Factor Hnf1/lfb1 In Cells of Hepatic and Nonhepatic Origin 41
Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen ama1: Report on a phase 1a clinical trial 41
New viral vectors for infectious diseases and cancer 40
A dna/ki67-based flow cytometry assay for cell cycle analysis of antigen-specific CD8 T cells in vaccinated mice 40
Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model 39
Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells 36
Promoter of the Pertussis Toxin Operon and Production of Pertussis Toxin 35
Chimpanzee adenovirus- and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults 35
Replicative conditioning of Herpes simplex type 1 virus by Survivin promoter, combined to ERBB2 retargeting, improves tumour cell-restricted oncolysis 35
Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation. 33
Translating the Immunogenicity of Prime-boost Immunization With ChAd63 and MVA ME-TRAP From Malaria Naive to Malaria-endemic Populations 33
Chronic Hepatitis C Virus infection subverts vaccine induced T-cell immunity in humans 33
Derivation of vaccines from mimotopes. Immunologic properties of human hepatitis B virus surface antigen mimotopes displayed on filamentous phage. 32
A Human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo 32
A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory 32
Novel genetically-modified chimpanzee adenovirus and MVA-vectored respiratory syncytial virus vaccine safely boosts humoral and cellular immunity in healthy older adults 32
Adenovirus type 4 and 7 vaccination or adenovirus type 4 respiratory infection elicits minimal cross-reactive antibody responses to nonhuman adenovirus vaccine vectors 31
Safety and immunogenicity of malaria vectored vaccines given with routine expanded program on immunization vaccines in gambian infants and neonates: A randomized controlled trial 31
Anti body-selected mimics of hepatitis C virus hypervariable region 1 activate both primary and memory Th lymphocytes 30
Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class II invariant chain 30
A phase Ia study to assess the safety and immunogenicity of new malaria vaccine candidates ChAd63 CS administered alone and with MVA CS 30
Fusion of HCV nonstructural antigen to MHC class II-associated invariant chain enhances T-cell responses induced by vectored vaccines in nonhuman primates 30
Cholesterol conjugation potentiates the antiviral activity of an HIV immunoadhesin 30
Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment 30
Identification of biologically active peptides using random libraries displayed on phage. 29
Efficacy of a virus-vectored vaccine against human and bovine respiratory syncytial virus infections 29
High-Throughput Monoclonal Antibody Discovery from Phage Libraries: Challenging the Current Preclinical Pipeline to Keep the Pace with the Increasing mAb Demand 29
A novel adenovirus type 6 (Ad6)-based hepatitis C virus vector that overcomes preexisting anti-Ad5 immunity and induces potent and broad cellular immune responses in rhesus macaques 28
A Myosin-like Dimerization Helix and An Extra-large Homeodomain Are Essential Elements of the Tripartite Dna-binding Structure of Lfb1 28
A general strategy to identify mimotopes of pathological antigens using only random peptide libraries and human sera. 28
Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents 28
Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults 28
Longitudinal transcriptomic and genetic landscape of radiotherapy response in canine melanoma 28
2 Different Liver-specific Factors Stimulate Invitro Transcription From the Human Alpha-1-antitrypsin Promoter 27
A complex interplay of positive and negative elements is responsible for the different transcriptional activity of liver NF1 variants. 27
Absence of systemic toxicity changes following intramuscular administration of novel pSG2.HIVconsv DNA, ChAdV63.HIVconsv and MVA.HIVconsv vaccines to BALB/c mice. 27
T-cell immunity and hepatitis C virus reinfection after cure of chronic hepatitis C with an interferon-free antiviral regimen in a chimpanzee 27
Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice 27
Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants 26
Immune profiling of premalignant lesions in patients with Lynch syndrome 26
MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans 26
An adenovirus type 5 (Ad5) amplicon-based packaging cell line for production of high-capacity helper-independent Delta E1-E2-E3-E4 Ad5 vectors 25
Identification and Characterization of Hepatocyte-specific Regulatory Regions of the Rat Pyruvate-kinase L-gene - the Synergistic Effects of Multiple Elements 25
Antibody Response To Respiratory Syncytial Virus Infection In Children <18 Months Old 25
Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins 24
Chimpanzee Adenovirus Vector Ebola Vaccine - Preliminary Report 24
Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals 24
Chimpanzee adenoviral vectors as vaccines–challenges to move the technology into the fast lane 24
Mucosal delivery of a vectored RSV vaccine is safe and elicits protective immunity in rodents and nonhuman primates 24
A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees 23
Genetic vaccination by gene electro-transfer in non-human primates 23
A model for the hepatitis C virus envelope glycoprotein E2 23
The X-ray structure of an atypical homeodomain present in the rat liver transcription factor LFB1/HNF1 and implications for DNA binding. 23
Epitope discovery using peptide libraries displayed on phage. 23
A database system for handling phage library-derived sequences. 23
Production and characterization of high-titer serum-free cell culture grown hepatitis C virus particles of genotype 1-6 23
Safety and immunogenicity of novel respiratory syncytial virus (RSV) vaccines based on the RSV viral proteins F, N and M2-1 encoded by simian adenovirus (PanAd3-RSV) and MVA (MVA-RSV); Protocol for an open-label, dose-escalation, single-centre, phase 1 clinical trial in healthy adults 23
Antigen-specific CD8 T cells in cell cycle circulate in the blood after vaccination 23
Novel Human Anti-PD-L1 mAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling 23
A novel Chimpanzee serotype-based adenoviral vector as delivery tool for cancer vaccines 22
Alteration In L-type Pyruvate-kinase Gene-expression Is Not Associated With the Lf-b1 Messenger-rna Level 22
Cloning and Sequencing of the Pertussis Toxin Genes - Operon Structure and Gene Duplication 22
A Novel Vaccine Strategy Employing Serologically Different Chimpanzee Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection 22
Enhancing blood-stage malaria subunit vaccine immunogenicity in rhesus macaques by combining adenovirus, poxvirus, and protein-in-adjuvant vaccines. 21
Identification of peptides binding to IgG in the CSF of multiple sclerosis patients 21
Development of chimpanzee adenoviruses as vaccine vectors: challenges and successes emerging from clinical trials. 21
Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regimen elicits T cell and neutralizing antibody immune responses 21
Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP 21
Exposure to hepatitis C virus induces cellular immune responses without detectable viremia or seroconversion 20
Hypervariable region 1 deletion and required adaptive envelope mutations confer decreased dependency on scavenger receptor class B type I and low-density lipoprotein receptor for hepatitis C virus. 20
Incidence and Risk Factors for Hepatitis C Virus Infection among Illicit Drug Users in Italy 20
A first-in-human study of the novel HIV-fusion inhibitor C34-PEG4-Chol 20
Differential Screening of Phage-Ab Libraries by Oligonucleotide Microarray Technology 19
Cross-reactive phage-displayed mimotopes lead to the discovery of mimicry between HSV-1 and a brain-specific protein 19
High prevalence of hypervariable region 1-specific and -cross-reactive CD4(+) T cells in HCV-infected individuals responsive to IFN-alpha treatment 19
Antibody responses to hepatitis C virus hypervariable region 1: Evidence for cross-reactivity and immune-mediated sequence variation 19
Synchronous division induced in Escherichia coli K12 by gemts mutants of phage Mu. 19
Peptide and protein display on the surface of filamentous bacteriophage. 19
Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies 19
A next generation vaccine against human rabies based on a single dose of a chimpanzee adenovirus vector serotype c 19
The kinetics of hepatitis C virus-specific CD8 T-cell responses in the blood mirror those in the liver in acute hepatitis C virus infection 18
Hepatitis C virus carriers with persistently normal ALT levels: biological peculiarities and update of the natural history of liver disease at 10 years 18
Bacteriophage lambda display of complex cDNA libraries: A new approach to functional genomics 18
Mimotopes of the hepatitis C virus hypervariable region 1, but not the natural sequences, induce cross-reactive antibody response by genetic immunization 18
Enhancing B- and T-cell immune response to a hepatitis C virus E2 DNA vaccine by intramuscular electrical gene transfer 18
Identification of amino acid residues in CD81 critical for interaction with hepatitis C virus envelope glycoprotein E2 18
Monoclonal antibodies (mAB) with broad specificity for a large repertoire of HCV variants 18
Promoter Elements and Factors Involved In Hepatic Transcription of the Human Apoa-i Gene Positive and Negative Regulators Bind To Overlapping Sites 18
A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA 18
Totale 2.838
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Categoria #
all - tutte 20.724
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.724
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020135 0 0 0 0 4 3 23 3 7 14 56 25
2020/202165 4 3 9 3 2 12 1 10 8 4 9 0
2021/2022810 8 2 12 4 11 36 34 33 210 22 57 381
2022/20231.047 178 78 6 115 124 130 1 86 160 102 50 17
2023/2024591 32 81 74 29 31 62 9 57 9 34 130 43
2024/2025541 234 233 22 18 34 0 0 0 0 0 0 0
Totale 3.714