IRIS
NICOSIA, Alfredo
 Distribuzione geografica
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Continente #
AS - Asia 3.903
NA - Nord America 3.173
EU - Europa 2.730
SA - Sud America 592
AF - Africa 86
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 10.488
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Nazione #
US - Stati Uniti d'America 2.997
SG - Singapore 2.244
RU - Federazione Russa 1.460
CN - Cina 794
BR - Brasile 495
HK - Hong Kong 434
IT - Italia 359
VN - Vietnam 223
IE - Irlanda 170
DE - Germania 157
FI - Finlandia 153
NL - Olanda 136
CA - Canada 122
GB - Regno Unito 104
IN - India 55
AR - Argentina 39
FR - Francia 38
MX - Messico 34
CI - Costa d'Avorio 30
AT - Austria 28
SE - Svezia 26
BD - Bangladesh 24
ZA - Sudafrica 24
EC - Ecuador 19
PL - Polonia 15
UA - Ucraina 15
ID - Indonesia 14
KR - Corea 14
CO - Colombia 13
IQ - Iraq 13
ES - Italia 12
TR - Turchia 12
RO - Romania 11
PK - Pakistan 10
UZ - Uzbekistan 10
JP - Giappone 9
LT - Lituania 9
BE - Belgio 8
VE - Venezuela 8
AE - Emirati Arabi Uniti 7
JO - Giordania 6
PY - Paraguay 6
TN - Tunisia 6
CH - Svizzera 5
AZ - Azerbaigian 4
CL - Cile 4
DZ - Algeria 4
HN - Honduras 4
IL - Israele 4
RS - Serbia 4
AL - Albania 3
BO - Bolivia 3
ET - Etiopia 3
GE - Georgia 3
JM - Giamaica 3
KE - Kenya 3
LB - Libano 3
LK - Sri Lanka 3
MA - Marocco 3
OM - Oman 3
UY - Uruguay 3
AO - Angola 2
AU - Australia 2
BF - Burkina Faso 2
BG - Bulgaria 2
GH - Ghana 2
LV - Lettonia 2
MD - Moldavia 2
MY - Malesia 2
NI - Nicaragua 2
PA - Panama 2
PT - Portogallo 2
TH - Thailandia 2
ZW - Zimbabwe 2
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
BB - Barbados 1
BH - Bahrain 1
BJ - Benin 1
BS - Bahamas 1
BY - Bielorussia 1
BZ - Belize 1
CM - Camerun 1
CR - Costa Rica 1
CU - Cuba 1
CZ - Repubblica Ceca 1
EE - Estonia 1
EG - Egitto 1
EU - Europa 1
GF - Guiana Francese 1
HT - Haiti 1
IR - Iran 1
IS - Islanda 1
KH - Cambogia 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LU - Lussemburgo 1
LY - Libia 1
ME - Montenegro 1
MO - Macao, regione amministrativa speciale della Cina 1
Totale 10.477
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Città #
Singapore 975
Chandler 461
Hong Kong 433
Moscow 356
Beijing 273
Santa Clara 239
Ashburn 226
Millbury 149
Naples 136
Amsterdam 127
Nanjing 121
Princeton 113
Los Angeles 106
Boston 100
Ottawa 87
Ho Chi Minh City 73
Hefei 67
Redondo Beach 66
Des Moines 62
Buffalo 58
Hanoi 56
The Dalles 55
Munich 53
Lawrence 51
Wilmington 47
New York 43
São Paulo 40
Napoli 32
Hebei 31
Dallas 30
Nanchang 30
Helsinki 27
Shenyang 27
Tianjin 23
Frankfurt am Main 21
Jiaxing 21
Dearborn 20
Denver 20
Orem 19
Rio de Janeiro 19
Chicago 18
Mexico City 18
Falkenstein 17
Milan 17
Nuremberg 17
London 16
Falls Church 15
Changsha 14
Belo Horizonte 13
Chennai 13
Montreal 13
Vienna 13
Brooklyn 12
Curitiba 12
Da Nang 12
Norwalk 12
Seattle 12
Seoul 12
Toronto 12
Biên Hòa 11
Pune 11
Rome 11
Stockholm 11
Warsaw 11
Houston 10
Manchester 10
Porto Alegre 10
Tashkent 10
San Francisco 9
Atlanta 8
Johannesburg 8
Lappeenranta 8
Quito 8
San Jose 8
Tokyo 8
Washington 8
Bologna 7
Council Bluffs 7
Dhaka 7
Haiphong 7
Marano 7
Phoenix 7
Poplar 7
Salt Lake City 7
Tampa 7
Amman 6
Bengaluru 6
Brasília 6
Brussels 6
Campinas 6
Columbus 6
Erbil 6
Guarulhos 6
Maceió 6
Manaus 6
Ankara 5
Boardman 5
Düsseldorf 5
Guayaquil 5
Hải Dương 5
Totale 5.469
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Nome #
Generation of a novel mesothelin-targeted oncolytic herpes virus and implemented strategies for manufacturing 155
Integrity of the antiviral STING-mediated DNA sensing in tumor cells is required to sustain the immunotherapeutic efficacy of herpes simplex oncolytic virus 151
A dna/ki67-based flow cytometry assay for cell cycle analysis of antigen-specific CD8 T cells in vaccinated mice 140
A genetic vaccine encoding shared cancer neoantigens to treat tumors with microsatellite instability 131
Novel human anti-Claudin 1 monoclonal antibodies inhibit HCV infection and may synergize with anti-SRB1 mAb. 126
Rapid Affinity Maturation of Novel Anti-PD-L1 Antibodies by a Fast Drop of the Antigen Concentration and FACS Selection of Yeast Libraries 119
Generation of a retargeted oncolytic herpes virus encoding adenosine deaminase for tumor adenosine clearance 118
Massive parallel screening of phage libraries for the generation of repertoires of human immunomodulatory monoclonal antibodies. 116
A long non-coding SINEUP RNA boosts semi-stable production of fully human monoclonal antibodies in HEK293E cells 116
One-Step Recovery of scFv Clones from High-Throughput Sequencing-Based Screening of Phage Display Libraries Challenged to Cells Expressing Native Claudin-1 114
Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells 114
Prime and pull of Tcell responses against cancer-exogenous antigens is effective against CPI-resistant tumors 110
MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans 110
Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment 106
New viral vectors for infectious diseases and cancer 104
Replicative conditioning of Herpes simplex type 1 virus by Survivin promoter, combined to ERBB2 retargeting, improves tumour cell-restricted oncolysis 103
Novel Human Anti-PD-L1 mAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling 101
High-Throughput Monoclonal Antibody Discovery from Phage Libraries: Challenging the Current Preclinical Pipeline to Keep the Pace with the Increasing mAb Demand 101
Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice 98
Peptide nucleic acid-mediated circularization of target RNA as tool to inhibit translation 94
Chimpanzee adenovirus- and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults 94
A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory 93
Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation. 92
A phase Ia study to assess the safety and immunogenicity of new malaria vaccine candidates ChAd63 CS administered alone and with MVA CS 89
Longitudinal transcriptomic and genetic landscape of radiotherapy response in canine melanoma 88
Derivation of vaccines from mimotopes. Immunologic properties of human hepatitis B virus surface antigen mimotopes displayed on filamentous phage. 85
Identification of biologically active peptides using random libraries displayed on phage. 85
Chimpanzee adenoviral vectors as vaccines–challenges to move the technology into the fast lane 85
The X-ray structure of an atypical homeodomain present in the rat liver transcription factor LFB1/HNF1 and implications for DNA binding. 84
Home delivery of the communicator for remote monitoring of cardiac implantable devices: A multicenter experience during the covid-19 lockdown 83
Efficacy of a virus-vectored vaccine against human and bovine respiratory syncytial virus infections 81
Mucosal delivery of a vectored RSV vaccine is safe and elicits protective immunity in rodents and nonhuman primates 81
Monoclonal antibodies that recognise filamentous phage: tools for phage display technology. 80
Promoter of the Pertussis Toxin Operon and Production of Pertussis Toxin 80
Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants 80
Novel genetically-modified chimpanzee adenovirus and MVA-vectored respiratory syncytial virus vaccine safely boosts humoral and cellular immunity in healthy older adults 79
Recognition by human sera and immunogenicity of HBsAg mimotopes selected from an M13 phage display library. 77
Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling 77
Chronic Hepatitis C Virus infection subverts vaccine induced T-cell immunity in humans 75
Phage-displayed peptides as tools for characterization of human sera. 74
Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge 74
A next generation vaccine against human rabies based on a single dose of a chimpanzee adenovirus vector serotype c 74
Anti body-selected mimics of hepatitis C virus hypervariable region 1 activate both primary and memory Th lymphocytes 73
Synchronous division induced in Escherichia coli K12 by gemts mutants of phage Mu. 73
A Bipartite Activation Domain Is Responsible For the Activity of Transcription Factor Hnf1/lfb1 In Cells of Hepatic and Nonhepatic Origin 73
Epitope discovery using peptide libraries displayed on phage. 72
Peptide and protein display on the surface of filamentous bacteriophage. 72
A Myosin-like Dimerization Helix and An Extra-large Homeodomain Are Essential Elements of the Tripartite Dna-binding Structure of Lfb1 70
Highly-Immunogenic Virally-Vectored T-cell Vaccines Cannot Overcome Subversion of the T-cell Response by HCV during Chronic Infection 70
Safety and immunogenicity of malaria vectored vaccines given with routine expanded program on immunization vaccines in gambian infants and neonates: A randomized controlled trial 69
Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model 68
Absence of systemic toxicity changes following intramuscular administration of novel pSG2.HIVconsv DNA, ChAdV63.HIVconsv and MVA.HIVconsv vaccines to BALB/c mice. 68
A Human monoclonal antibody targeting scavenger receptor class B type I precludes hepatitis C virus infection and viral spread in vitro and in vivo 68
Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen ama1: Report on a phase 1a clinical trial 68
Genetic vaccination by gene electro-transfer in non-human primates 67
Incidence and Risk Factors for Hepatitis C Virus Infection among Illicit Drug Users in Italy 67
Cloning and Sequencing of the Pertussis Toxin Genes - Operon Structure and Gene Duplication 66
Adenovirus type 4 and 7 vaccination or adenovirus type 4 respiratory infection elicits minimal cross-reactive antibody responses to nonhuman adenovirus vaccine vectors 66
A novel adenovirus type 6 (Ad6)-based hepatitis C virus vector that overcomes preexisting anti-Ad5 immunity and induces potent and broad cellular immune responses in rhesus macaques 65
Safety and immunogenicity of novel respiratory syncytial virus (RSV) vaccines based on the RSV viral proteins F, N and M2-1 encoded by simian adenovirus (PanAd3-RSV) and MVA (MVA-RSV); Protocol for an open-label, dose-escalation, single-centre, phase 1 clinical trial in healthy adults 65
Translating the Immunogenicity of Prime-boost Immunization With ChAd63 and MVA ME-TRAP From Malaria Naive to Malaria-endemic Populations 64
Immune profiling of premalignant lesions in patients with Lynch syndrome 64
Identification and Characterization of Hepatocyte-specific Regulatory Regions of the Rat Pyruvate-kinase L-gene - the Synergistic Effects of Multiple Elements 63
A first-in-human study of the novel HIV-fusion inhibitor C34-PEG4-Chol 62
A complex interplay of positive and negative elements is responsible for the different transcriptional activity of liver NF1 variants. 61
Clinical assessment of a recombinant simian adenovirus ChAd63: a potent new vaccine vector. 61
Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults 61
An adenovirus type 5 (Ad5) amplicon-based packaging cell line for production of high-capacity helper-independent Delta E1-E2-E3-E4 Ad5 vectors 60
Development of chimpanzee adenoviruses as vaccine vectors: challenges and successes emerging from clinical trials. 60
Chimpanzee Adenovirus Vector Ebola Vaccine - Preliminary Report 60
Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants with in vitro resistance to SR-BI-targeting agents 60
Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication. 59
A novel Chimpanzee serotype-based adenoviral vector as delivery tool for cancer vaccines 59
A general strategy to identify mimotopes of pathological antigens using only random peptide libraries and human sera. 59
Cholesterol conjugation potentiates the antiviral activity of an HIV immunoadhesin 59
Promoter Elements and Factors Involved In Hepatic Transcription of the Human Apoa-i Gene Positive and Negative Regulators Bind To Overlapping Sites 58
Alteration In L-type Pyruvate-kinase Gene-expression Is Not Associated With the Lf-b1 Messenger-rna Level 57
Role of scavenger receptor class B type I in hepatitis C virus entry: kinetics and molecular determinants. 56
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus 56
Cross-reactive phage-displayed mimotopes lead to the discovery of mimicry between HSV-1 and a brain-specific protein 56
2 Different Liver-specific Factors Stimulate Invitro Transcription From the Human Alpha-1-antitrypsin Promoter 56
Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class II invariant chain 56
T-cell immunity and hepatitis C virus reinfection after cure of chronic hepatitis C with an interferon-free antiviral regimen in a chimpanzee 56
Fusion of HCV nonstructural antigen to MHC class II-associated invariant chain enhances T-cell responses induced by vectored vaccines in nonhuman primates 56
Exposure to hepatitis C virus induces cellular immune responses without detectable viremia or seroconversion 55
Expression and Immunological Properties of the 5 Subunits of Pertussis Toxin 55
Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins 54
Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals 54
A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA 54
Antibody Response To Respiratory Syncytial Virus Infection In Children <18 Months Old 54
A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees 53
High-avidity monoclonal antibodies against the human scavenger class B type I receptor efficiently block hepatitis C virus infection in the presence of high-density lipoprotein 53
A database system for handling phage library-derived sequences. 53
Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults. 53
Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies 53
Variability or conservation of hepatitis C virus hypervariable region 1? Implications for immune responses 52
High prevalence of hypervariable region 1-specific and -cross-reactive CD4(+) T cells in HCV-infected individuals responsive to IFN-alpha treatment 52
Enhancing B- and T-cell immune response to a hepatitis C virus E2 DNA vaccine by intramuscular electrical gene transfer 52
Efficient display of an HCV cDNA expression library as C-terminal fusion to the capsid protein D of bacteriophage lambda 52
Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regimen elicits T cell and neutralizing antibody immune responses 52
Totale 7.647
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Categoria #
all - tutte 39.576
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.576
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202144 0 0 0 0 0 12 1 10 8 4 9 0
2021/2022810 8 2 12 4 11 36 34 33 210 22 57 381
2022/20231.047 178 78 6 115 124 130 1 86 160 102 50 17
2023/2024591 32 81 74 29 31 62 9 57 9 34 130 43
2024/20253.668 234 233 22 18 40 264 294 212 470 435 1.125 321
2025/20263.777 804 476 531 527 1.119 320 0 0 0 0 0 0
Totale 10.618