PEPE, STEFANO
PEPE, STEFANO
DIPARTIMENTO DI ENDOCRINOLOGIA ED ONCOLOGIA MOLECOLARE E CLINICA (attivo dal 01/01/1994 al 31/12/2012)
Retroviral vector-mediated overexpression of the RIIbeta subunit of the cAMP-dependent protein kinase induces differentiation in human leukemia cells and reverts the transformed phenotype of mouse fibroblasts.
1994 Tortora, Giampaolo; Budillon, A.; Clair, T.; Pepe, Stefano; Yokozaki, H.; Merlo, G.; Rohlff, C.; Cho Chung, Y. S.
Epidermal growth factor (EGFR) and Transferrin (TRFR) receptor upregulation is induced by arabinoside cytosine (ARA-C) on human tumor cells.
1993 M., Caraglia; P., Correale; G., Genua; Pepe, Stefano; DEL VECCHIO, Silvana; G., Esposito; Bianco, ANGELO RAFFAELE; P. T. a. g. l. i. a. f. e. r. r., I.
Hereditary and familial breast and ovarian cancer: spectrum of related tumors.
2008 Pepe, Stefano
Differential sensitivity to non-MHC-restricted rIL-2 activated lymphocyte killing of human mammary epithelial MCF-10A cells overexpressing oncogenes or PKA subunits.
1996 Tagliaferri, P.; Tortora, Giampaolo; Guarrasi, R.; Damiano, Vincenzo; Ruggiero, A.; Morelli, D.; Caraglia, M.; Bianco, Roberto; di Isernia, G.; Pepe, Stefano; Arteaga, C. L.; Langton Webster, B. C.; Bianco, A. R.; Ciardiello, F.
In vitro cytotoxicity of VP-16213 on human ovarian cancer.
1984 L., Morasca; E., Erba; M., Vaghi; G., Amato; Pepe, Stefano; C., Mangioni; N., Colombo; F., Landoni; M. D. '. I. n. c. a. l. c., I.
Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective EGFR-tyrosine kinase inhibitor ZD1839 (‘Iressa’)
2002 Bianco, C; Tortora, Giampaolo; Bianco, Roberto; Caputo, R; Veneziani, BIANCA MARIA; Caputo, R; Damiano, Vincenzo; Troiani, T; Fontanini, G; Raben, D; Pepe, Stefano; Bianco, Ar
Studio osservazionale sorveglianza diagnostica di donne ad alto rischio genetico-familiare di tumore mammario (ISSIN-HIBCR)
2008 Pepe, Stefano
TSH-regulated growth and cell cycle distribution of thyroid cells involve type I isozyme of cAMP-dependent protein kinase
1993 Tortora, Giampaolo; Pepe, Stefano; Cirafici, A. M.; Ciardiello, F.; Porcellini, Antonio; Clair, T.; Colletta, G.; Cho Chung, Y. S.; Bianco, A. R.
Le neoplasie eredo-familiari della mammella, dell'ovaio e del colon retto. Aspetti clininci, diagnostici e teraputici.
2010 Pepe, Stefano
Breast cancer prevention with fenretinide in young women at gentic and familial risk. A phase III randomized clinical trial
2010 Pepe, Stefano
Phase I clinical study with 8-Chloro-cAMP and evaluation of immunological effects in cancer patients.
1995 Tortora, Giampaolo; Ciardiello, F.; Pepe, Stefano; Tagliaferri, P.; Ruggiero, A.; Bianco, C.; Guarrasi, R.; Miki, K.; Bianco, A. R.
Synergistic inhibition of growth and induction of apoptosis by 8-chloro-cAMP and paclitaxel or cisplatin in human cancer cells.
1997 Tortora, Giampaolo; DI ISERNIA, G; Sandomenico, C; Bianco, Roberto; Pomatico, G; Pepe, Stefano; Bianco, Ar; Ciardiello, F.
Cooperative antitumor effect of mixed backbone oligonucleotides targeting protein kinase A in combination with cytotoxic drugs or biologic agents.
1998 Tortora, Giampaolo; Caputo, R; Damiano, Vincenzo; Bianco, Roberto; Pepe, Stefano; Pomatico, G; Bianco, Ar; Jiang, Z; Agrawal, S; Ciardiello, F.
Differential effects of type I and type II protein kinase A isoforms on chinese hamster ovary cell cycle and proliferation.
1994 Tortora, Giampaolo; Pepe, Stefano; Bianco, C.; Damiano, Vincenzo; Ruggiero, A.; Baldassarre, G.; Corbo, C.; Cho Chung, Y. S.; Bianco, A. R.; Ciardiello, F.
The RIalfa subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells.
1994 Tortora, Giampaolo; Pepe, Stefano; Bianco, C.; Baldassarre, G.; Budillon, A.; Clair, T.; Cho Chung, Y. S.; Bianco, A. R.; Ciardiello, F.
Overexpression of wild-type p53 ovverrides the mitogenic effect of the RIa subunit of protein kinase A in human breast cells.
1995 Damiano, Vincenzo; F., Ciardiello; C., Bianco; G., Baldassarre; G., Di Isernia; Pepe, Stefano; A., Ruggiero; G., Merlo; Bianco, ANGELO RAFFAELE; Tortora, Giampaolo
Cooperative inhibitory effect of novel mixed backbone oligonucleotide targeting Protein Kinase A in combination with docetaxel and anti-EGFR-Receptor antibody on human breast cancer cell growth.
1999 Tortora, Giampaolo; Caputo, R; Pomatico, G; Pepe, Stefano; Bianco, A. R.; Agrawal, S; Mendelsohn, J; Ciardiello, F.
The cAMP-dependent protein kinase type I is involved in hypersensitivity of human breast cells to topoisomerase II inhibitors.
1995 Tortora, Giampaolo; Ciardiello, F.; Damiano, Vincenzo; Pepe, Stefano; Bianco, C.; di Isernia, G.; Davies, S. L.; North, P.; Harris, A. L.; Hickson, I. D.; Bianco, A. R.
Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225.
1999 Ciardiello, F; Bianco, Roberto; Damiano, Vincenzo; DE LORENZO, Sonya; Pepe, Stefano; DE PLACIDO, Sabino; Fan, Z; Mendelsohn, J; Bianco, A. R.; Tortora, Giampaolo
Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A.
1997 Tortora, Giampaolo; Caputo, R; Damiano, Vincenzo; Bianco, Roberto; Pepe, Stefano; Bianco, Ar; Jiang, Z; Agrawal, S; Ciardiello, F.
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| Retroviral vector-mediated overexpression of the RIIbeta subunit of the cAMP-dependent protein kinase induces differentiation in human leukemia cells and reverts the transformed phenotype of mouse fibroblasts. | 1.1 Articolo in rivista | 1994 | Tortora, Giampaolo; Budillon, A.; Clair, T.; Pepe, Stefano; Yokozaki, H.; Merlo, G.; Rohlff, C.; Cho Chung, Y. S. | |
| Epidermal growth factor (EGFR) and Transferrin (TRFR) receptor upregulation is induced by arabinoside cytosine (ARA-C) on human tumor cells. | 1.1 Articolo in rivista | 1993 | M., Caraglia; P., Correale; G., Genua; Pepe, Stefano; DEL VECCHIO, Silvana; G., Esposito; Bianco, ANGELO RAFFAELE; P. T. a. g. l. i. a. f. e. r. r., I. | |
| Hereditary and familial breast and ovarian cancer: spectrum of related tumors. | 8.10 Tesi di Dottorato | 2008 | Pepe, Stefano | |
| Differential sensitivity to non-MHC-restricted rIL-2 activated lymphocyte killing of human mammary epithelial MCF-10A cells overexpressing oncogenes or PKA subunits. | 1.1 Articolo in rivista | 1996 | Tagliaferri, P.; Tortora, Giampaolo; Guarrasi, R.; Damiano, Vincenzo; Ruggiero, A.; Morelli, D.; Caraglia, M.; Bianco, Roberto; di Isernia, G.; Pepe, Stefano; Arteaga, C. L.; Langton Webster, B. C.; Bianco, A. R.; Ciardiello, F. | |
| In vitro cytotoxicity of VP-16213 on human ovarian cancer. | 1.1 Articolo in rivista | 1984 | L., Morasca; E., Erba; M., Vaghi; G., Amato; Pepe, Stefano; C., Mangioni; N., Colombo; F., Landoni; M. D. '. I. n. c. a. l. c., I. | |
| Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective EGFR-tyrosine kinase inhibitor ZD1839 (‘Iressa’) | 1.1 Articolo in rivista | 2002 | Bianco, C; Tortora, Giampaolo; Bianco, Roberto; Caputo, R; Veneziani, BIANCA MARIA; Caputo, R; Damiano, Vincenzo; Troiani, T; Fontanini, G; Raben, D; Pepe, Stefano; Bianco, Ar | |
| Studio osservazionale sorveglianza diagnostica di donne ad alto rischio genetico-familiare di tumore mammario (ISSIN-HIBCR) | 8.07 Progetti di Ricerca Finanziati | 2008 | Pepe, Stefano | |
| TSH-regulated growth and cell cycle distribution of thyroid cells involve type I isozyme of cAMP-dependent protein kinase | 1.1 Articolo in rivista | 1993 | Tortora, Giampaolo; Pepe, Stefano; Cirafici, A. M.; Ciardiello, F.; Porcellini, Antonio; Clair, T.; Colletta, G.; Cho Chung, Y. S.; Bianco, A. R. | |
| Le neoplasie eredo-familiari della mammella, dell'ovaio e del colon retto. Aspetti clininci, diagnostici e teraputici. | 8.04 Convegni organizzati dalla struttura | 2010 | Pepe, Stefano | |
| Breast cancer prevention with fenretinide in young women at gentic and familial risk. A phase III randomized clinical trial | 8.07 Progetti di Ricerca Finanziati | 2010 | Pepe, Stefano | |
| Phase I clinical study with 8-Chloro-cAMP and evaluation of immunological effects in cancer patients. | 1.1 Articolo in rivista | 1995 | Tortora, Giampaolo; Ciardiello, F.; Pepe, Stefano; Tagliaferri, P.; Ruggiero, A.; Bianco, C.; Guarrasi, R.; Miki, K.; Bianco, A. R. | |
| Synergistic inhibition of growth and induction of apoptosis by 8-chloro-cAMP and paclitaxel or cisplatin in human cancer cells. | 1.1 Articolo in rivista | 1997 | Tortora, Giampaolo; DI ISERNIA, G; Sandomenico, C; Bianco, Roberto; Pomatico, G; Pepe, Stefano; Bianco, Ar; Ciardiello, F. | |
| Cooperative antitumor effect of mixed backbone oligonucleotides targeting protein kinase A in combination with cytotoxic drugs or biologic agents. | 1.1 Articolo in rivista | 1998 | Tortora, Giampaolo; Caputo, R; Damiano, Vincenzo; Bianco, Roberto; Pepe, Stefano; Pomatico, G; Bianco, Ar; Jiang, Z; Agrawal, S; Ciardiello, F. | |
| Differential effects of type I and type II protein kinase A isoforms on chinese hamster ovary cell cycle and proliferation. | 1.1 Articolo in rivista | 1994 | Tortora, Giampaolo; Pepe, Stefano; Bianco, C.; Damiano, Vincenzo; Ruggiero, A.; Baldassarre, G.; Corbo, C.; Cho Chung, Y. S.; Bianco, A. R.; Ciardiello, F. | |
| The RIalfa subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells. | 1.1 Articolo in rivista | 1994 | Tortora, Giampaolo; Pepe, Stefano; Bianco, C.; Baldassarre, G.; Budillon, A.; Clair, T.; Cho Chung, Y. S.; Bianco, A. R.; Ciardiello, F. | |
| Overexpression of wild-type p53 ovverrides the mitogenic effect of the RIa subunit of protein kinase A in human breast cells. | 1.1 Articolo in rivista | 1995 | Damiano, Vincenzo; F., Ciardiello; C., Bianco; G., Baldassarre; G., Di Isernia; Pepe, Stefano; A., Ruggiero; G., Merlo; Bianco, ANGELO RAFFAELE; Tortora, Giampaolo | |
| Cooperative inhibitory effect of novel mixed backbone oligonucleotide targeting Protein Kinase A in combination with docetaxel and anti-EGFR-Receptor antibody on human breast cancer cell growth. | 1.1 Articolo in rivista | 1999 | Tortora, Giampaolo; Caputo, R; Pomatico, G; Pepe, Stefano; Bianco, A. R.; Agrawal, S; Mendelsohn, J; Ciardiello, F. | |
| The cAMP-dependent protein kinase type I is involved in hypersensitivity of human breast cells to topoisomerase II inhibitors. | 1.1 Articolo in rivista | 1995 | Tortora, Giampaolo; Ciardiello, F.; Damiano, Vincenzo; Pepe, Stefano; Bianco, C.; di Isernia, G.; Davies, S. L.; North, P.; Harris, A. L.; Hickson, I. D.; Bianco, A. R. | |
| Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225. | 1.1 Articolo in rivista | 1999 | Ciardiello, F; Bianco, Roberto; Damiano, Vincenzo; DE LORENZO, Sonya; Pepe, Stefano; DE PLACIDO, Sabino; Fan, Z; Mendelsohn, J; Bianco, A. R.; Tortora, Giampaolo | |
| Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A. | 1.1 Articolo in rivista | 1997 | Tortora, Giampaolo; Caputo, R; Damiano, Vincenzo; Bianco, Roberto; Pepe, Stefano; Bianco, Ar; Jiang, Z; Agrawal, S; Ciardiello, F. |