PEPE, STEFANO
PEPE, STEFANO
DIPARTIMENTO DI ENDOCRINOLOGIA ED ONCOLOGIA MOLECOLARE E CLINICA (attivo dal 01/01/1994 al 31/12/2012)
Phase I clinical study with 8-Chloro-cAMP and evaluation of immunological effects in cancer patients.
1995 Tortora, Giampaolo; Ciardiello, F.; Pepe, Stefano; Tagliaferri, P.; Ruggiero, A.; Bianco, C.; Guarrasi, R.; Miki, K.; Bianco, A. R.
Cooperative antitumor effect of mixed backbone oligonucleotides targeting protein kinase A in combination with cytotoxic drugs or biologic agents.
1998 Tortora, Giampaolo; Caputo, R; Damiano, Vincenzo; Bianco, Roberto; Pepe, Stefano; Pomatico, G; Bianco, Ar; Jiang, Z; Agrawal, S; Ciardiello, F.
The cAMP-dependent protein kinase type I is involved in hypersensitivity of human breast cells to topoisomerase II inhibitors.
1995 Tortora, Giampaolo; Ciardiello, F.; Damiano, Vincenzo; Pepe, Stefano; Bianco, C.; di Isernia, G.; Davies, S. L.; North, P.; Harris, A. L.; Hickson, I. D.; Bianco, A. R.
A phase I/II trial of gefitinib and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck.
2008 F., Caponigro; Romano, Carmela; A., Milano; Solla, Raffaele; G., Franchin; V., Adamo; E., Mari; B., Morrica; Pepe, Stefano
Sequence-dependent, synergistic antiproliferative and proapoptotic effects of the combination of cytotoxic drugs and enzastaurin, a protein kinase C beta inhibitor, in non-small cell lung cancer cells.
2008 F., Morgillo; E., Martinelli; Troiani, Teresa; Laus, Gianluca; Pepe, Stefano; C., Gridelli; F. C. i. a. r. d. i. e. l. l., O.
Retroviral vector-mediated overexpression of the RIIbeta subunit of the cAMP-dependent protein kinase induces differentiation in human leukemia cells and reverts the transformed phenotype of mouse fibroblasts.
1994 Tortora, Giampaolo; Budillon, A.; Clair, T.; Pepe, Stefano; Yokozaki, H.; Merlo, G.; Rohlff, C.; Cho Chung, Y. S.
Differential sensitivity to non-MHC-restricted rIL-2 activated lymphocyte killing of human mammary epithelial MCF-10A cells overexpressing oncogenes or PKA subunits.
1996 Tagliaferri, P.; Tortora, Giampaolo; Guarrasi, R.; Damiano, Vincenzo; Ruggiero, A.; Morelli, D.; Caraglia, M.; Bianco, Roberto; di Isernia, G.; Pepe, Stefano; Arteaga, C. L.; Langton Webster, B. C.; Bianco, A. R.; Ciardiello, F.
TSH-regulated growth and cell cycle distribution of thyroid cells involve type I isozyme of cAMP-dependent protein kinase
1993 Tortora, Giampaolo; Pepe, Stefano; Cirafici, A. M.; Ciardiello, F.; Porcellini, Antonio; Clair, T.; Colletta, G.; Cho Chung, Y. S.; Bianco, A. R.
Enzastaurin inhibits tumors sensitive and resistant to anti-EGFR drugs
2008 Gelardi, Teresa; Caputo, R; Damiano, Vincenzo; Daniele, Gennaro; Pepe, Stefano; Ciardiello, F; Lahn, M; Bianco, Roberto; Tortora, Giampaolo
8-Chloro-cAMP enhances the growth inhibitory effect of cytotoxic drugs in human colon cancer cells
1996 di Isernia, G.; Ciardiello, F.; Sandomenico, C.; Pepe, Stefano; Bianco, A. R.; Tortora, Giampaolo
Differential effects of type I and type II protein kinase A isoforms on chinese hamster ovary cell cycle and proliferation.
1994 Tortora, Giampaolo; Pepe, Stefano; Bianco, C.; Damiano, Vincenzo; Ruggiero, A.; Baldassarre, G.; Corbo, C.; Cho Chung, Y. S.; Bianco, A. R.; Ciardiello, F.
The RIalfa subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells.
1994 Tortora, Giampaolo; Pepe, Stefano; Bianco, C.; Baldassarre, G.; Budillon, A.; Clair, T.; Cho Chung, Y. S.; Bianco, A. R.; Ciardiello, F.
Loss of thyrotropin regulation and trasforming growth factor beta-induced growth arrest in erbB-2 overexpressing rat thyroid cells.
1993 G., Mincione; A. M., Cirafici; D., Lazzareschi; Pepe, Stefano; F., Ciardiello; G. C. o. l. l. e. t. t., A.
Markers of cell proliferation as prognostic factors in differentiated thyroid cancer.
1993 F., Basolo; L., Fugazzola; G., Fontanini; R., Elisei; Pepe, Stefano; G., Bevilacqua; A., Pinchera; F. P. a. c. i. n., I.
Quality control for the evaluation of the S-phase fraction by flow cytometry: a multicentric study.
1994 R., Silvestrini; the SICCAB Group for quality control of cell kinetic, Determinations; Pepe, Stefano
Cyclic AMP-dependent protein kinase type I is involved in hypersensitivity of human breast cells to topoisomerase II inhibitors.
1995 Tortora, Giampaolo; F., Ciardiello; Damiano, Vincenzo; Pepe, Stefano; C., Bianco; G., di Isernia; S. L., Davies; P., North; A. L., Harris; I. D., Hickson; Bianco, ANGELO RAFFAELE
NM23 gene expression correlates with cell growth rate and S-phase.
1995 M. A., Caligo; G., Cipollini; L., Fiore; S., Calvo; F., Basolo; P., Collecchi; F., Ciardiello; Pepe, Stefano; M., Petrini; G. B. e. v. i. l. a. c. q. u., A.
Sequence-dependent antiproliferative effects of cytotoxic drugs and epidermal growth factor receptor inhibitors.
2005 M. P., Morelli; T., Cascone; Troiani, Teresa; F., De Vita; M., Orditura; Laus, Gianluca; S. G., Eckhardt; Pepe, Stefano; Tortora, Giampaolo; F. C. i. a. r. d. i. e. l. l., O.
Poly(ADPR)polymerase-1 signalling of the DNA damage induced by DNA topoisomerase I poison in D54p53wt and U251p53mut glioblastoma cell lines.
2007 Cimmino, Gabriella; Pepe, Stefano; Laus, Gianluca; M., Chianese; D., Prece; R., Penitente; Quesada, PIERINA MARIA
Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-A in head and neck cancer cells in vitro and in vivo
2006 F., Bruzzese; E., Di Gennaro; A., Avallone; Pepe, Stefano; C., Arra; M., Caraglia; P., Tagliaferri; A. B. u. d. i. l. l. o., N.
| Titolo | Tipologia | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|---|
| Phase I clinical study with 8-Chloro-cAMP and evaluation of immunological effects in cancer patients. | 1.1 Articolo in rivista | 1995 | Tortora, Giampaolo; Ciardiello, F.; Pepe, Stefano; Tagliaferri, P.; Ruggiero, A.; Bianco, C.; Guarrasi, R.; Miki, K.; Bianco, A. R. | |
| Cooperative antitumor effect of mixed backbone oligonucleotides targeting protein kinase A in combination with cytotoxic drugs or biologic agents. | 1.1 Articolo in rivista | 1998 | Tortora, Giampaolo; Caputo, R; Damiano, Vincenzo; Bianco, Roberto; Pepe, Stefano; Pomatico, G; Bianco, Ar; Jiang, Z; Agrawal, S; Ciardiello, F. | |
| The cAMP-dependent protein kinase type I is involved in hypersensitivity of human breast cells to topoisomerase II inhibitors. | 1.1 Articolo in rivista | 1995 | Tortora, Giampaolo; Ciardiello, F.; Damiano, Vincenzo; Pepe, Stefano; Bianco, C.; di Isernia, G.; Davies, S. L.; North, P.; Harris, A. L.; Hickson, I. D.; Bianco, A. R. | |
| A phase I/II trial of gefitinib and radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck. | 1.1 Articolo in rivista | 2008 | F., Caponigro; Romano, Carmela; A., Milano; Solla, Raffaele; G., Franchin; V., Adamo; E., Mari; B., Morrica; Pepe, Stefano | |
| Sequence-dependent, synergistic antiproliferative and proapoptotic effects of the combination of cytotoxic drugs and enzastaurin, a protein kinase C beta inhibitor, in non-small cell lung cancer cells. | 1.1 Articolo in rivista | 2008 | F., Morgillo; E., Martinelli; Troiani, Teresa; Laus, Gianluca; Pepe, Stefano; C., Gridelli; F. C. i. a. r. d. i. e. l. l., O. | |
| Retroviral vector-mediated overexpression of the RIIbeta subunit of the cAMP-dependent protein kinase induces differentiation in human leukemia cells and reverts the transformed phenotype of mouse fibroblasts. | 1.1 Articolo in rivista | 1994 | Tortora, Giampaolo; Budillon, A.; Clair, T.; Pepe, Stefano; Yokozaki, H.; Merlo, G.; Rohlff, C.; Cho Chung, Y. S. | |
| Differential sensitivity to non-MHC-restricted rIL-2 activated lymphocyte killing of human mammary epithelial MCF-10A cells overexpressing oncogenes or PKA subunits. | 1.1 Articolo in rivista | 1996 | Tagliaferri, P.; Tortora, Giampaolo; Guarrasi, R.; Damiano, Vincenzo; Ruggiero, A.; Morelli, D.; Caraglia, M.; Bianco, Roberto; di Isernia, G.; Pepe, Stefano; Arteaga, C. L.; Langton Webster, B. C.; Bianco, A. R.; Ciardiello, F. | |
| TSH-regulated growth and cell cycle distribution of thyroid cells involve type I isozyme of cAMP-dependent protein kinase | 1.1 Articolo in rivista | 1993 | Tortora, Giampaolo; Pepe, Stefano; Cirafici, A. M.; Ciardiello, F.; Porcellini, Antonio; Clair, T.; Colletta, G.; Cho Chung, Y. S.; Bianco, A. R. | |
| Enzastaurin inhibits tumors sensitive and resistant to anti-EGFR drugs | 1.1 Articolo in rivista | 2008 | Gelardi, Teresa; Caputo, R; Damiano, Vincenzo; Daniele, Gennaro; Pepe, Stefano; Ciardiello, F; Lahn, M; Bianco, Roberto; Tortora, Giampaolo | |
| 8-Chloro-cAMP enhances the growth inhibitory effect of cytotoxic drugs in human colon cancer cells | 1.1 Articolo in rivista | 1996 | di Isernia, G.; Ciardiello, F.; Sandomenico, C.; Pepe, Stefano; Bianco, A. R.; Tortora, Giampaolo | |
| Differential effects of type I and type II protein kinase A isoforms on chinese hamster ovary cell cycle and proliferation. | 1.1 Articolo in rivista | 1994 | Tortora, Giampaolo; Pepe, Stefano; Bianco, C.; Damiano, Vincenzo; Ruggiero, A.; Baldassarre, G.; Corbo, C.; Cho Chung, Y. S.; Bianco, A. R.; Ciardiello, F. | |
| The RIalfa subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells. | 1.1 Articolo in rivista | 1994 | Tortora, Giampaolo; Pepe, Stefano; Bianco, C.; Baldassarre, G.; Budillon, A.; Clair, T.; Cho Chung, Y. S.; Bianco, A. R.; Ciardiello, F. | |
| Loss of thyrotropin regulation and trasforming growth factor beta-induced growth arrest in erbB-2 overexpressing rat thyroid cells. | 1.1 Articolo in rivista | 1993 | G., Mincione; A. M., Cirafici; D., Lazzareschi; Pepe, Stefano; F., Ciardiello; G. C. o. l. l. e. t. t., A. | |
| Markers of cell proliferation as prognostic factors in differentiated thyroid cancer. | 1.1 Articolo in rivista | 1993 | F., Basolo; L., Fugazzola; G., Fontanini; R., Elisei; Pepe, Stefano; G., Bevilacqua; A., Pinchera; F. P. a. c. i. n., I. | |
| Quality control for the evaluation of the S-phase fraction by flow cytometry: a multicentric study. | 1.1 Articolo in rivista | 1994 | R., Silvestrini; the SICCAB Group for quality control of cell kinetic, Determinations; Pepe, Stefano | |
| Cyclic AMP-dependent protein kinase type I is involved in hypersensitivity of human breast cells to topoisomerase II inhibitors. | 1.1 Articolo in rivista | 1995 | Tortora, Giampaolo; F., Ciardiello; Damiano, Vincenzo; Pepe, Stefano; C., Bianco; G., di Isernia; S. L., Davies; P., North; A. L., Harris; I. D., Hickson; Bianco, ANGELO RAFFAELE | |
| NM23 gene expression correlates with cell growth rate and S-phase. | 1.1 Articolo in rivista | 1995 | M. A., Caligo; G., Cipollini; L., Fiore; S., Calvo; F., Basolo; P., Collecchi; F., Ciardiello; Pepe, Stefano; M., Petrini; G. B. e. v. i. l. a. c. q. u., A. | |
| Sequence-dependent antiproliferative effects of cytotoxic drugs and epidermal growth factor receptor inhibitors. | 1.1 Articolo in rivista | 2005 | M. P., Morelli; T., Cascone; Troiani, Teresa; F., De Vita; M., Orditura; Laus, Gianluca; S. G., Eckhardt; Pepe, Stefano; Tortora, Giampaolo; F. C. i. a. r. d. i. e. l. l., O. | |
| Poly(ADPR)polymerase-1 signalling of the DNA damage induced by DNA topoisomerase I poison in D54p53wt and U251p53mut glioblastoma cell lines. | 1.1 Articolo in rivista | 2007 | Cimmino, Gabriella; Pepe, Stefano; Laus, Gianluca; M., Chianese; D., Prece; R., Penitente; Quesada, PIERINA MARIA | |
| Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-A in head and neck cancer cells in vitro and in vivo | 1.1 Articolo in rivista | 2006 | F., Bruzzese; E., Di Gennaro; A., Avallone; Pepe, Stefano; C., Arra; M., Caraglia; P., Tagliaferri; A. B. u. d. i. l. l. o., N. |