IRIS
LEOSCO, DARIO
 Distribuzione geografica
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Continente #
AS - Asia 7.612
EU - Europa 6.336
NA - Nord America 6.035
SA - Sud America 1.273
AF - Africa 224
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 8
Totale 21.497
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Nazione #
US - Stati Uniti d'America 5.742
SG - Singapore 4.348
RU - Federazione Russa 3.261
CN - Cina 1.534
BR - Brasile 1.045
IT - Italia 806
HK - Hong Kong 739
DE - Germania 637
VN - Vietnam 505
FI - Finlandia 385
NL - Olanda 285
IE - Irlanda 281
CA - Canada 164
IN - India 143
GB - Regno Unito 139
UA - Ucraina 129
SE - Svezia 122
AR - Argentina 104
MX - Messico 85
CI - Costa d'Avorio 75
FR - Francia 74
ZA - Sudafrica 63
BD - Bangladesh 54
PL - Polonia 44
TR - Turchia 42
ID - Indonesia 38
EC - Ecuador 35
IQ - Iraq 32
ES - Italia 29
AT - Austria 25
JP - Giappone 23
VE - Venezuela 22
KR - Corea 19
LT - Lituania 18
PK - Pakistan 18
CL - Cile 16
CO - Colombia 16
UZ - Uzbekistan 16
AZ - Azerbaigian 14
MA - Marocco 14
CZ - Repubblica Ceca 13
PY - Paraguay 13
AL - Albania 12
KE - Kenya 12
AE - Emirati Arabi Uniti 10
BE - Belgio 10
PE - Perù 10
BG - Bulgaria 9
CH - Svizzera 9
TN - Tunisia 9
DZ - Algeria 8
IL - Israele 8
JM - Giamaica 8
KZ - Kazakistan 8
DK - Danimarca 7
PH - Filippine 7
RS - Serbia 7
SA - Arabia Saudita 7
HN - Honduras 6
IR - Iran 6
MY - Malesia 6
TT - Trinidad e Tobago 6
AU - Australia 5
BA - Bosnia-Erzegovina 5
BO - Bolivia 5
SN - Senegal 5
TH - Thailandia 5
BS - Bahamas 4
DO - Repubblica Dominicana 4
EU - Europa 4
JO - Giordania 4
LB - Libano 4
MZ - Mozambico 4
PS - Palestinian Territory 4
PT - Portogallo 4
RO - Romania 4
UY - Uruguay 4
EG - Egitto 3
GR - Grecia 3
KW - Kuwait 3
LK - Sri Lanka 3
NG - Nigeria 3
NZ - Nuova Zelanda 3
BB - Barbados 2
BY - Bielorussia 2
CV - Capo Verde 2
CW - ???statistics.table.value.countryCode.CW??? 2
EE - Estonia 2
ET - Etiopia 2
GA - Gabon 2
GE - Georgia 2
GH - Ghana 2
GP - Guadalupe 2
GY - Guiana 2
HR - Croazia 2
LU - Lussemburgo 2
ME - Montenegro 2
MK - Macedonia 2
NI - Nicaragua 2
NO - Norvegia 2
Totale 21.449
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Città #
Singapore 1.911
Moscow 781
Hong Kong 737
Ashburn 568
Chandler 560
Beijing 477
Millbury 304
Dallas 276
Amsterdam 268
Santa Clara 265
Princeton 263
Naples 246
Nanjing 237
Los Angeles 226
Ho Chi Minh City 186
Boston 168
Napoli 156
Munich 133
Des Moines 120
Jacksonville 110
Buffalo 107
Redondo Beach 106
Ottawa 95
Hanoi 94
New York 93
São Paulo 91
Hefei 88
Wilmington 84
Turku 73
Nanchang 72
The Dalles 63
San Jose 61
Mexico City 57
Shenyang 57
Hebei 52
Seattle 49
Houston 44
Orem 43
Chicago 42
Helsinki 39
Warsaw 37
Brooklyn 36
Jiaxing 36
Tianjin 36
Kochi 35
Rio de Janeiro 33
Johannesburg 32
Stockholm 32
Montreal 30
Changsha 28
Dong Ket 28
Da Nang 27
Denver 27
Frankfurt am Main 27
Washington 27
Lawrence 26
Phoenix 26
Belo Horizonte 25
Chennai 24
Norwalk 24
Nuremberg 24
Mumbai 23
London 22
Atlanta 21
Casavatore 21
Curitiba 21
Milan 20
Tokyo 20
Poplar 19
Ankara 18
Manchester 18
Falls Church 17
Rome 17
Guayaquil 16
Pune 16
Boardman 15
Brasília 15
San Francisco 15
Tashkent 15
Woodbridge 15
Biên Hòa 14
Campinas 14
Haiphong 14
Baku 13
Charlotte 13
Seoul 13
Toronto 13
Dublin 11
Falkenstein 11
Kronberg 11
Porto Alegre 11
Baghdad 10
Brno 10
Dhaka 10
Nairobi 10
Ninh Bình 10
Pozzuoli 10
Tirana 10
Vienna 10
Ann Arbor 9
Totale 10.593
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Nome #
Imbalance Between Interleukin-1β and Interleukin-1 Receptor Antagonist in Epicardial Adipose Tissue Is Associated With Non ST-Segment Elevation Acute Coronary Syndrome 150
Epicardial adipose tissue has an increased thickness and is a source of inflammatory mediators in patients with calcific aortic stenosis 148
Insulin resistance is associated with impaired cardiac sympathetic innervation in patients with heart failure 146
β-adrenergic receptors and G protein-coupled receptor kinase-2 in Alzheimer's disease: a new paradigm for prognosis and therapy? 141
Autonomic dysfunction in Alzheimer's disease: tools for assessment and review of the literature 141
Statin therapy modulates thickness and inflammatory profile of human epicardial adipose tissue 138
Increased epicardial adipose tissue volume correlates with cardiac sympathetic denervation in patients with heart failure 137
Adipokines and coronary artery disease 130
Impact of diabetes mellitus on lymphocyte GRK2 protein levels in patients with heart failure 130
Effects of exercise training on cardiovascular adrenergic system 130
Sleep-disordered breathing, impaired cardiac adrenergic innervation and prognosis in heart failure 130
Immediate and long-term outcome of recanalization of chronic total coronary occlusions. 128
The aging heart: presbycardia [Il cuore senile: la presbicardia] 128
Changes of plasma norepinephrine and serum N-terminal pro-brain natriuretic peptide after exercise training predict survival in patients with heart failure 128
Sleep-disordered breathing and epicardial adipose tissue in patients with heart failure. 128
Infectious endocarditis after transcatheter aortic valve implantation in a patient on oral therapy with glucocorticoids 127
Aortic rupture in patient on oral therapy with levofloxacin 126
Exercise restores age-dependent impairment of angiogenesis in rats. 125
Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease 125
Impact of Malnutrition on Long-Term Mortality in Elderly Patients with Acute Myocardial Infarction. 125
Adrenal adrenoceptors in heart failure 124
Age-related and heart failure-related beta-adrenergic receptor dysfunction: New therapeutic strategies for the treatment of cardiovascular diseases 124
Prognostic Value of Lymphocyte G Protein-Coupled Receptor Kinase-2 Protein Levels in Patients With Heart Failure 123
Isolated Valve Amyloid Deposition in Aortic Stenosis: Potential Clinical and Pathophysiological Relevance 121
The G protein coupled receptor kinase 2 plays an essential role in beta-adrenergic receptor-induced insulin resistance. 121
Exercise training early after acute myocardial infarction reduces stress-induced hypoperfusion and improves left ventricular function 121
Alterations of left ventricular deformation and cardiac sympathetic derangement in patients with systolic heart failure: a 3D speckle tracking echocardiography and cardiac ¹²³I-MIBG study 121
Advances in treatment strategies of hypertension in elderly subjects: very low dose combination in first line. 120
B1-Adrenergic Receptor and Sphingosine-1-Phosphate Receptor 1 (S1PR1) Reciprocal Downregulation Influences Cardiac Hypertrophic Response and Progression to Heart Failure: Protective Role of S1PR1 Cardiac Gene Therapy 119
Cardiac beta 1-adrenergic receptor blockade promotes angiogenesis in the post-ischemic failing heart via activation of VEGF- and Akt-dependent signalling pathway 117
Reduction of lymphocyte G protein-coupled receptor kinase-2 (GRK2) after exercise training predicts survival in patients with heart failure. 117
Myocardial β2-adrenoceptor gene delivery promotes coordinated cardiac adaptive remodelling and angiogenesis in heart failure 116
Validation of the echocardiographic assessment of epicardial adipose tissue thickness at the Rindfleisch fold for the prediction of coronary artery disease 116
Impact of aging on cardiac sympathetic innervation measured by (123)I-mIBG imaging in patients with systolic heart failure 115
beta-2 adrenergic receptors overexpression promotes angiogenesis in the falling myocardium through activation of vascular endothelial growth factor/Akt transduction pathway 114
Coinvolgimento del signaling β-adrenergico nella malattia di Alzheimer 114
Epicardial Adipose Tissue-Derived IL-1β Triggers Postoperative Atrial Fibrillation 113
Negative impact of β-arrestin-1 on post-myocardial infarction heart failure via cardiac and adrenal-dependent neurohormonal mechanisms 113
β-Adrenergic Receptor Signaling and Heart Failure: From Bench to Bedside 113
Exercise stimulates angiogenesis and improves beta-adrenergic receptor signaling in the failing heart 112
Prothymosin alpha protects cardiomyocytes against ischemia-induced apoptosis via preservation of Akt activation. 112
Long-Term Caloric Restriction Improves Cardiac Function, Remodeling, Adrenergic Responsiveness, and Sympathetic Innervation in a Model of Postischemic Heart Failure 112
Calcific aortic stenosis: A peculiar feature of diastolic heart failure in the elderly 112
G protein-coupled receptor kinase-2 svolge un ruolo cruciale nella regolare della funzione endoteliale in vivo e in vitro attraverso la modulazione del signaling del recettore B2-adrenergico. 111
βARKct gene-therapy improves β2-adrenergic receptor-dependent neoangiogenesis following hindlimb ischemia 110
Ruolo del β-bloccante sull’iperattività del Sistema Nervoso Simpatico e sulla produzione di catecolamine recettore α2 -adrenergico-dipendente dalla midollare del surrene in corso di scompenso. 109
Statins and the elderly: Recent evidence and current indications 109
Epicardial Adipose Tissue and Postoperative Atrial Fibrillation 109
beta-1 adrenergic receptor blokade and cardiac beta-2 overexpression stimulates angiogenesis in the failing heart 108
Renal function and cardiac adrenergic impairment in patients affected by heart failure 107
The elderly at risk: aldosterone as modulator of the immune response to SARS-CoV-2 infection 105
Ruolo dell’attività fisica sulla prognosi di pazienti anziani affetti da cardiopatia ischemica e sottoposti ad intervento di by-pass aorto-coronarico. 104
Efficacia e sicurezza della terapia con anticoagulanti rispetto agli antiaggreganti nell’insufficienza cardiac in ritmo sinusale: una revision sistematica con meta-analisi. 104
A new approach to percutaneous coronary revascularization in patients requiring undeferrable non-cardiac surgery 103
I livelli di G-protein Coupled Receptor Kinase-2 (GRK2) linfocitaria predicono la mortalità in pazienti affetti da scompenso cardiaco avanzato. 103
Prognostic Value of Lymphocyte G Protein-Coupled Receptor Kinase-2 (grk2) Protein Levels in Patients With Heart Failure 103
Echocardiographic Epicardial Adipose Tissue Thickness for Risk Stratification of Patients With Heart Failure 103
Diabetes is Associated With Higher Lymphocyte G-Protein Coupled Receptor Kinase-2 (grk2) Protein Levels in Patients With Left Ventricle Dysfunction Independently From Heart Failure Status 102
The lipid theory in the pathogenesis of calcific aortic stenosis 102
Proinflammatory phenotype of cardiac visceral fat in heart failure with preserved ejection fraction in the elderly 101
β-adrenergic receptor responsiveness in aging heart and clinical implications 100
Predisposing factors to heart failure in diabetic nephropathy: a look at the sympathetic nervous system hyperactivity 100
Epicardial Adipose Tissue and Cardiac Arrhythmias: Focus on Atrial Fibrillation 99
Lymphocyte G-protein-coupled receptor kinase-2 is upregulated in patients with Alzheimer's disease. 99
Molecular aspects of the cardioprotective effect of exercise in the elderly 99
Inflammation and Cardiovascular Diseases in the Elderly: The Role of Epicardial Adipose Tissue 99
Genetic test for dilated and hypertrophic cardiomyopathies: useful or less than useful for patients? 98
G protein-coupled receptor kinase-2 regola la funzione dei recettori alfa2-adrenergici ed il rilascio di catecolamine nelle cellule cromaffini umane della midollare del surrene. 98
Exercise-induced reduction of lymphocyte G-protein coupled receptor kinase-2 (GRK2) strongly predicts improved survival in patients with heart failure. 97
Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases 97
Pressure injuries in elderly with acute myocardial infarction 97
β-adrenergic receptor involvment in Alzheimer disease 97
Sudden onset of coma in a 70-year-old woman with cryoglobulinemia 95
Effects of Chronic Exercise on Restoring Age-impaired VEGF Up-reguation and Angiogenetic Responses to Hindlimb Ischemia. 95
Blockade of ??-adrenoceptors restores the GRK2-mediated adrenal ??(2) -adrenoceptor-catecholamine production axis in heart failure 95
Correction to :β adrenergic receptor kinase C-terminal peptide gene-therapy improves ß2-adrenergic receptor-dependent neoangiogenesis after hindlimb ischemia (Journal of Pharmacology and Experimental Therapeutics (2016) 356:2 (503–513) DOI: 10.1124/jpet.115.228411) 94
[From bench to bedside: new insights into the treatment of heart failure]. 93
Prevalence and severity of asymptomatic coronary and carotid artery disease in patients with lower limbs arterial disease 93
Vantaggi del trattamento endoprotesico degli aneurismi aortici in categorie ad alto rischio chirurgico 93
β1-Blockade Prevents Post-Ischemic Myocardial Decompensation Via β3AR-Dependent Protective Sphingosine-1 Phosphate Signaling 93
L’ipertrofia miocardia da sovraccarico pressorio induce un notevole incremento dell’espressione di C-Flip, una proteina indispensabile per lo sviluppo embrionale del cuore 92
GRK2 blockade with betaARKct is essential for cardiac beta2-adrenergic receptor signaling towards increased contractility. 92
Red Flags, Prognostic Impact, and Management of Patients With Cardiac Amyloidosis and Aortic Valve Stenosis: A Systematic Review and Meta-Analysis 92
The role of inflammation and metabolic risk factors in the pathogenesis of calcific aortic valve stenosis 91
Risk of acute myocardial infarction after transurethral resection of prostate in elderly 90
Oral anticoagulation therapy in heart failure patients in sinus rhythm: a systematic review and meta-analysis. 90
Epidemiology and risk factors for heart failure in the elderly 89
Reperfusion Correlates and Clinical Outcomes of Right Ventricular Dysfunction in Patients With Inferior ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention 89
Vantaggi del trattamento endoprotesico degli aneurismi aortici in categorie ad alto rischio chirurgico. 88
Prior exercise improves age-dependent vascular endothelial growth factor downregulation and angiogenesis responses to hind-limb ischemia in old rats. 88
Genetic Test for the Channelopaties: Useful or Less Than Useful for Patients? (Part II) 88
Na-Ca exchange in the regulation of electrical and mechanical cardiac activity 87
Two-dimensional echocardiographic evaluation of ventricular asynergy induced by dipyridamole: correlation with thallium scanning. 87
Targeting the β-adrenergic receptor system through G-protein-coupled receptor kinase 2: a new paradigm for therapy and prognostic evaluation in heart failure: from bench to bedside 87
Inhibition of G-protein coupled receptor kinese 2 (grk2) by in vivo gene transfer enhances neoangiogenesis in a rat model of hindlimb ischemia. 86
Beta-adrenergic Receptor Blockade Reduces Sympathetic Overactivation in Heart Failure and Restores Adrenal GRK2-alfa2-adrenergic Receptor-cathecolamine Production Axis. 86
Verapamil reduces dipyridamole-induced myocardial ischemia in patients with coronary artery disease 84
The role of endovascular therapy in the treatment of the aortic aneurysms in high-risk subsets. 84
DIABETES IS ASSOCIATED WITH HIGHER CARDIAC SYMPATHETIC DENERVATION IN PATIENTS WITH LEFT VENTRICLE DYSFUNCTION INDEPENDENTLY FROM HEART FAILURE STATUS 84
Extraction-Free Absolute Quantification of Circulating miRNAs by Chip-Based Digital PCR 83
Totale 10.832
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Categoria #
all - tutte 77.292
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 77.292
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021160 0 0 0 0 0 0 24 12 49 9 29 37
2021/20221.490 17 1 4 5 6 65 10 75 309 113 220 665
2022/20231.578 290 77 45 92 176 171 4 128 247 252 79 17
2023/20241.332 40 184 221 88 95 139 36 154 13 24 220 118
2024/20257.094 413 416 26 108 131 240 896 379 492 741 2.632 620
2025/20267.910 1.496 725 1.460 1.189 2.320 647 73 0 0 0 0 0
Totale 21.852