IRIS
MARINELLI, LUCIANA
 Distribuzione geografica
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Continente #
AS - Asia 6.770
NA - Nord America 6.497
EU - Europa 5.108
SA - Sud America 834
Continente sconosciuto - Info sul continente non disponibili 398
AF - Africa 202
OC - Oceania 3
Totale 19.812
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Nazione #
US - Stati Uniti d'America 6.231
SG - Singapore 2.958
RU - Federazione Russa 2.184
CN - Cina 1.289
VN - Vietnam 1.281
IT - Italia 1.166
BR - Brasile 663
HK - Hong Kong 483
DE - Germania 364
NL - Olanda 252
FR - Francia 242
FI - Finlandia 199
CA - Canada 168
IE - Irlanda 168
GB - Regno Unito 144
BD - Bangladesh 131
IN - India 124
JP - Giappone 112
UA - Ucraina 101
SE - Svezia 79
AR - Argentina 76
CI - Costa d'Avorio 71
IQ - Iraq 58
KR - Corea 49
MX - Messico 47
TR - Turchia 46
ZA - Sudafrica 46
PH - Filippine 41
ES - Italia 37
PL - Polonia 34
EC - Ecuador 29
ID - Indonesia 29
AT - Austria 26
TH - Thailandia 26
BE - Belgio 25
PK - Pakistan 20
TW - Taiwan 18
VE - Venezuela 18
CO - Colombia 14
MA - Marocco 14
LT - Lituania 12
CH - Svizzera 11
PY - Paraguay 11
AZ - Azerbaigian 10
CL - Cile 10
ET - Etiopia 10
IR - Iran 9
JM - Giamaica 9
MY - Malesia 9
BG - Bulgaria 8
EG - Egitto 8
UZ - Uzbekistan 8
AE - Emirati Arabi Uniti 7
DZ - Algeria 7
IL - Israele 7
JO - Giordania 7
LB - Libano 7
TN - Tunisia 7
TT - Trinidad e Tobago 7
CZ - Repubblica Ceca 6
NP - Nepal 6
PT - Portogallo 6
RS - Serbia 6
CG - Congo 5
CR - Costa Rica 5
EE - Estonia 5
HR - Croazia 5
KE - Kenya 5
NG - Nigeria 5
PA - Panama 5
PE - Perù 5
PS - Palestinian Territory 5
SA - Arabia Saudita 5
AO - Angola 4
EU - Europa 4
GR - Grecia 4
KZ - Kazakistan 4
RO - Romania 4
SY - Repubblica araba siriana 4
UY - Uruguay 4
AL - Albania 3
BZ - Belize 3
DO - Repubblica Dominicana 3
GT - Guatemala 3
HN - Honduras 3
LU - Lussemburgo 3
NE - Niger 3
NI - Nicaragua 3
OM - Oman 3
SN - Senegal 3
AF - Afghanistan, Repubblica islamica di 2
BB - Barbados 2
BH - Bahrain 2
BN - Brunei Darussalam 2
GE - Georgia 2
GF - Guiana Francese 2
HU - Ungheria 2
IS - Islanda 2
MD - Moldavia 2
ME - Montenegro 2
Totale 19.379
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Città #
Singapore 1.380
San Jose 1.111
Moscow 553
Chandler 524
Ashburn 469
Hong Kong 468
Beijing 390
Ho Chi Minh City 369
Hanoi 296
Naples 259
Santa Clara 250
Dallas 236
Amsterdam 226
Hefei 174
Millbury 173
Council Bluffs 166
Lauterbourg 158
Los Angeles 155
The Dalles 155
Napoli 149
Nanjing 142
Princeton 142
Jacksonville 107
Boston 99
Tokyo 94
Buffalo 81
Ottawa 77
Munich 74
New York 67
Woodbridge 67
Des Moines 65
São Paulo 64
Phoenix 62
Redondo Beach 58
Wilmington 58
Da Nang 56
Milan 55
Rome 55
Haiphong 54
Chicago 53
Houston 47
Seattle 43
Frankfurt am Main 39
Dong Ket 34
Nanchang 34
Helsinki 33
Brooklyn 32
Orem 30
Seoul 29
Warsaw 29
Denver 26
Düsseldorf 26
Hebei 26
Shenyang 26
Turku 26
Tianjin 25
Atlanta 24
Baghdad 24
Jiaxing 24
Mexico City 24
Brussels 22
Falkenstein 22
Toronto 22
Montreal 21
Johannesburg 20
Dearborn 19
Nürnberg 19
Poplar 19
San Francisco 19
Changsha 18
Dublin 18
Lawrence 18
Augusta 17
Chennai 17
Hải Dương 17
Ann Arbor 16
Norwalk 16
Nuremberg 16
Rio de Janeiro 16
Stockholm 16
Ankara 15
London 15
Shanghai 15
Tân Tiến 15
Belo Horizonte 14
Boardman 14
Guangzhou 14
Manchester 14
Biên Hòa 13
Florence 13
Kronberg 13
Lappeenranta 13
Leawood 13
Ninh Bình 13
Bologna 12
Can Tho 12
Porto Alegre 12
Campinas 11
Guayaquil 11
Kochi 11
Totale 10.423
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Nome #
Functional Selectivity Revealed by N-Methylation Scanning of Human Urotensin II and Related Peptides 242
Annurca (Malus pumila Miller cv. Annurca) apple as a functional food for the contribution to a healthy balance of plasma cholesterol levels: results of a randomized clinical trial 229
Pharmacophoric Modifications Lead to Superpotent avb3 Integrin Ligands with Suppressed a5b1 Activity 219
A Healthy Balance of Plasma Cholesterol by a Novel Annurca Apple-Based Nutraceutical Formulation: Results of a Randomized Trial 218
A reverse translational approach reveals the protective roles of Mangifera indica in inflammatory bowel disease 210
Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity 201
Screening Platform toward New Anti-HIV Aptamers Set on Molecular Docking and Fluorescence Quenching Techniques 199
Structural and conformational requisites in DNA quadruplex groove binding: Another piece to the puzzle 197
Click-Chemistry (CuAAC) Trimerization of an αvβ6 Integrin Targeting Ga-68-Peptide: Enhanced Contrast for in-Vivo PET Imaging of Human Lung Adenocarcinoma Xenografts 189
Endogenous vs Exogenous Allosteric Modulators in GPCRs: A dispute for shuttling CB1 among different membrane microenvironments 179
Shooting for selective drug-like DNA G-quadruplex binders 177
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors 177
Discovery of 2,3-Diaminoindole Derivatives as a Novel Class of NOD Antagonists 175
Development and Nanoparticle-Mediated Delivery of Novel MDM2/MDM4 Heterodimer Peptide Inhibitors to Enhance 5-Fluorouracil Nucleolar Stress in Colorectal Cancer Cells 173
Pharmacological folding chaperones act as allosteric ligands of Frizzled4 172
Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists 168
Paper-based electrochemical device for early detection of integrin αvβ6 expressing tumors 166
Targeting CXCR4 reverts the suppressive activity of T-regulatory cells in renal cancer 164
A New DNA Structural Motif: The G-Triplex 161
Long non-coding RNA containing ultraconserved genomic region 8 promotes bladder cancer tumorigenesis 158
Structure-Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist 158
Analysis of quadruplex ligands by displacement isothermal titration calorimetry 154
Targeting the Human Telomeric G-Quadruplex Through Virtual Screening Calculations 153
Ex.50.T aptamer impairs tumor–stroma cross-talk in breast cancer by targeting gremlin-1 151
Structural and conformational requisites in DNA quadruplex groove binding: Another piece to the puzzle 150
A more detailed picture of the interactions between Virtual Screening-derived Hits and the DNA G-Quadruplex: NMR, Molecular Modeling and ITC Studies 148
State-of-the-art methodologies for the discovery and characterization of DNA G-Quadruplex binders 147
Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design 146
Dual MET and SMO Negative Modulators Overcome Resistance to EGFR Inhibitors in Human Nonsmall Cell Lung Cancer 146
Disulfide bond replacement with 1,4‐ and 1,5‐disubstituted [1,2,3]‐triazole on C‐X‐C chemokine receptor type 4 (CXCR4) peptide ligands: small changes that make big differences 146
Structure-based lead optimization and biological evaluation of BAX direct activators as novel potential anticancer agents 144
Deepening bis-(thio)carbohydrazones conformational dynamics and hydrogen bond interactions in a non-protic solvent: DFT, molecular dynamics, NMR, and Raman investigations 143
Shooting for selective drug-like G-quadruplex binders: Evidence for telomeric DNA damage and tumor cell death 143
Structural and Conformational Requisites in DNA Quadruplex Groove Binding 142
Enriching the arsenal of pharmacological tools against mical2 142
A combined approach of structure‐based virtual screening and NMR to interrupt the PD‐1/PD‐L1 axis: Biphenyl‐benzimidazole containing compounds as novel PD‐L1 inhibitors 139
Probing integrin selectivity: rational design of highly active and selective ligands for the alpha5beta1 and alphavbeta3 integrin receptor. 139
Beyond radio-displacement techniques for Identification of CB1 Ligands: The First Application of a Fluorescence-quenching Assay 139
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme 136
Shooting for Selective Drug-Like DNA G-Quadruplex Binders 135
Breaking the dogma of the metal-coordinating carboxylate group in integrin ligands: introducing hydroxamic acids to the MIDAS to tune potency and selectivity 134
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists 134
Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death 134
Minute-timescale free-energy calculations reveal a pseudo-active state in the adenosine A2A receptor activation mechanism 133
Progresses in the pursuit of aldose reductase inhibitors: the structure-based lead optimization step. 133
Novel Quinolinonyl Diketo Acid Derivatives as HIV-1 Integrase Inhibitors: Design, Synthesis, and Biological Activities 132
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 131
Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach 130
Novel peptidomimetics as BACE-1 inhibitors: synthesis, molecular modeling, and biological studies 130
Ensemble-docking approach on BACE-1: pharmacophore perception and guidelines for drug design 129
New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer 129
Ligand-Based NMR Study of C-X-C Chemokine Receptor Type 4 (CXCR4)-Ligand Interactions on Living Cancer Cells 128
A more detailed picture of the interactions between virtual screening-derived hits and the DNA G-quadruplex: NMR, molecular modelling and ITC studies. 127
Elucidating the Binding Behavior of Highly Potent COX-2 Selective Inhibitors 127
From a Helix to a Small Cycle: Metadynamics-Inspired αvβ6 Integrin Selective Ligands 127
Boosting Fmoc Solid-Phase Peptide Synthesis by Ultrasonication 125
Chemical modifications in the seed region of miRNAs 221/222 increase the silencing performances in gastrointestinal stromal tumor cells 124
Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand 122
Benzofuroxane Derivatives as Multi-Effective Agents for the Treatment of Cardiovascular Diabetic Complications. Synthesis, Functional Evaluation, and Molecular Modeling Studies 121
Targeting Glioblastoma Stem Cells via EphA2: Structural Insights into the RNA Aptamer A40s for Precision Therapy 121
N-O-ISOPROPYL SULFONAMIDO-BASED HYDROXAMATES: KINETIC CHARACTERISATION OF A SERIES OF MMP-12/MMP-13 DUAL TARGET INHIBITORS. 120
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists 120
A stereoselective approach to peptidomimetic BACE1 inhibitors 120
CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme 118
Pharmacological targeting of smoothened receptor cysteine-rich domain by Budesonide promotes in vitro myelination 118
Design, synthesis and characterization of aryl bis-guanyl hydrazones as RNA binders of C9orf72 G4C2 extended repeats 117
Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts 117
Targeting the KRAS oncogene: Synthesis, physicochemical and biological evaluation of novel G-Quadruplex DNA binders 117
New 2-Heterocyclyl-imidazo[2,1-i]purin-5-one Derivatives as Potent and Selective Human A3Adenosine Receptor Antagonists 116
Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A(3) Adenosine Receptor Antagonists 115
Specific Targeting of Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. 2. Stereoselective Interaction to Overcome the Effects of Drug Resistant Mutations 114
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 113
Acetic Acid Aldose Reductase Inhibitors Bearing a Five-Membered Heterocyclic Core with Potent Topical Activity in a Visual Impairment Rat Model. 112
Design, Synthesis, and Biological Evaluation of 1-Phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as New Glycogen Synthase Kinase-3 beta Inhibitors 112
Novel Peptide-Based PET Probe for Non-invasive Imaging of C-X-C Chemokine Receptor Type 4 (CXCR4) in Tumors 112
Biselectivity of isoDGR Peptides for Fibronectin Binding Integrin Subtypes α5β1 and αvβ6: Conformational Control through Flanking Amino Acids 111
Protein Flexibility in Virtual Screening: The BACE-1 Case Study 111
Tandem Application of Virtual Screening and NMR Experiments in the Discovery of Brand New DNA Quaduplex Groove Binders 110
Novel N2-substituted pyrazolo[3,4-d]pyrimidine adenosine A3 receptor antagonists: inhibition of A3-mediated human glioblastoma cell proliferation 110
Basic Quinolinonyl Diketo Acid Derivatives as Inhibitors of HIV Integrase and their Activity against RNase H Function of Reverse Transcriptase 110
Identification of novel molecular scaffolds for the design of MMP-13 inhibitors: A first round of lead optimization. 107
Stable Peptides Instead of Stapled Peptides: Highly Potent αvβ6-Selective Integrin Ligands 107
Dual binding mode of SC-558 in COX-2: A new frontier in COX inhibition 106
The ring residue proline 8 is crucial for the thermal stability of the lasso peptide caulosegnin II 106
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors 106
Design, Synthesis, and Biological Evaluation of Novel Aminobisphosphonates Possessing an in Vivo Antitumor Activity Through a γδ -T Lymphocytes-Mediated Activation Mechanism. 105
Dual binding mode of SC-558 in COX-2: A new frontier in COX inhibition 105
Human recombinant beta-secretase immobilized enzyme reactor for fast hits' selection and characterization from a virtual screening library 105
Applicazione di Metodologie Computazionali nella Scoperta e Sviluppo di Nuovi Agenti per il Trattamento delle Malattie Parassitarie 104
Identification of anxiolytic/non sedative agents among indol-3-ylglyoxylamides acting as functionally selective agonists at the GABAA alfa2 benzodiazepine receptor 103
UROTENSIN-II PEPTIDE AGONISTS AND ANTAGONISTS: A COMPREHENSIVE SAR STUDY 103
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 103
Molecular View on the iRGD Peptide Binding Mechanism: Implications for Integrin Activity and Selectivity Profiles 103
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of non-camptothecin Topoisomerase I (Top1) inhibitors. 102
Site-directed Mutagenesis of Key Residues Unveiled a Novel Allosteric Site on Human Adenosine Kinase for Pyrrolobenzoxa(thia)zepinone Non-Nucleoside Inhibitors 102
Human integrin αvβ5: homology modeling and ligand binding. 101
The G-triplex DNA 101
Conformational Analysis of Furanoid e-Sugar Amino Acid Containing Cyclic Peptides by NMR Spectroscopy, Molecular Dynamics Simulation, and X-ray Crystallography: Evidence for a Novel Turn Structure 100
UT RECEPTOR LIGANDS. SWITCHING FROM AGONIST TO ANTAGONIST ACTIVITY 100
Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvβ3 100
Totale 13.608
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Categoria #
all - tutte 66.249
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 66.249
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022835 0 0 8 8 16 22 15 41 177 75 94 379
2022/20231.334 173 77 35 146 138 146 0 127 179 209 74 30
2023/2024799 50 106 119 54 43 53 34 119 12 15 133 61
2024/20254.813 218 301 27 73 101 284 487 338 366 453 1.707 458
2025/20269.161 1.015 692 1.086 765 1.558 364 1.076 533 1.013 584 234 241
2026/2027776 200 335 241 0 0 0 0 0 0 0 0 0
Totale 19.812