IRIS
GALIETTA, Luis Juan Vicente
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
AS - Asia 6.287
NA - Nord America 5.558
EU - Europa 2.867
SA - Sud America 700
Continente sconosciuto - Info sul continente non disponibili 252
AF - Africa 89
OC - Oceania 10
Totale 15.763
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 5.318
SG - Singapore 2.781
RU - Federazione Russa 1.421
CN - Cina 1.129
VN - Vietnam 1.030
BR - Brasile 577
HK - Hong Kong 573
IT - Italia 489
FR - Francia 221
JP - Giappone 203
NL - Olanda 192
BD - Bangladesh 134
DE - Germania 124
CA - Canada 117
GB - Regno Unito 105
IN - India 84
SE - Svezia 63
KR - Corea 59
UA - Ucraina 57
MX - Messico 54
AR - Argentina 41
PH - Filippine 37
TH - Thailandia 37
FI - Finlandia 34
IE - Irlanda 33
IQ - Iraq 32
TR - Turchia 28
ID - Indonesia 27
CO - Colombia 24
ZA - Sudafrica 22
ES - Italia 20
TW - Taiwan 20
EC - Ecuador 18
PK - Pakistan 16
PL - Polonia 16
AT - Austria 14
CR - Costa Rica 14
SA - Arabia Saudita 14
JO - Giordania 13
VE - Venezuela 12
IL - Israele 11
MA - Marocco 11
BE - Belgio 10
HN - Honduras 10
JM - Giamaica 10
CH - Svizzera 8
CI - Costa d'Avorio 8
CL - Cile 8
GT - Guatemala 8
UY - Uruguay 8
DO - Repubblica Dominicana 7
MY - Malesia 7
PY - Paraguay 7
RO - Romania 7
TN - Tunisia 7
TT - Trinidad e Tobago 7
UZ - Uzbekistan 7
AU - Australia 6
EE - Estonia 6
EG - Egitto 6
KE - Kenya 6
AL - Albania 5
DK - Danimarca 5
HR - Croazia 5
IR - Iran 5
KZ - Kazakistan 5
PE - Perù 5
BB - Barbados 4
CZ - Repubblica Ceca 4
DZ - Algeria 4
MD - Moldavia 4
NG - Nigeria 4
NP - Nepal 4
OM - Oman 4
AE - Emirati Arabi Uniti 3
AF - Afghanistan, Repubblica islamica di 3
BG - Bulgaria 3
ET - Etiopia 3
EU - Europa 3
HU - Ungheria 3
KH - Cambogia 3
KW - Kuwait 3
LT - Lituania 3
PA - Panama 3
PT - Portogallo 3
AZ - Azerbaigian 2
BS - Bahamas 2
BY - Bielorussia 2
CY - Cipro 2
GE - Georgia 2
GH - Ghana 2
GN - Guinea 2
LB - Libano 2
NC - Nuova Caledonia 2
RS - Serbia 2
XK - ???statistics.table.value.countryCode.XK??? 2
AO - Angola 1
BA - Bosnia-Erzegovina 1
BF - Burkina Faso 1
BN - Brunei Darussalam 1
Totale 15.485
Salva come PNG Salva come JPEG
Città #
Singapore 1.267
San Jose 768
Ashburn 610
Hong Kong 550
Chandler 490
Moscow 389
Santa Clara 304
Ho Chi Minh City 276
Hanoi 241
Hefei 230
Beijing 195
Tokyo 191
Council Bluffs 173
Amsterdam 170
Phoenix 167
Lawrence 166
Lauterbourg 159
Nanjing 143
Los Angeles 136
The Dalles 134
Des Moines 133
Naples 133
Boston 119
Millbury 108
Redondo Beach 78
Buffalo 71
São Paulo 68
New York 54
Dallas 51
Napoli 51
Seoul 48
Chicago 43
Ottawa 36
Da Nang 35
Shenyang 35
Haiphong 34
Hebei 33
Orem 31
Frankfurt am Main 30
Wilmington 30
Nanchang 29
Seattle 26
Changsha 24
Jiaxing 24
Milan 24
Mexico City 23
Dublin 22
Washington 22
Munich 21
Nuremberg 21
Toronto 21
Atlanta 19
Bangkok 19
Montreal 19
Rio de Janeiro 19
Helsinki 17
Jacksonville 17
Stockholm 17
Biên Hòa 16
Houston 16
Johannesburg 16
Tianjin 16
Brooklyn 15
Columbus 15
Hải Dương 15
Rome 15
Baghdad 14
Belo Horizonte 14
Warsaw 14
Philadelphia 13
Amman 12
Brighton 12
Chennai 12
Dhaka 12
London 12
Poplar 12
San Francisco 12
Brasília 11
Bến Tre 11
Edinburgh 11
Shanghai 11
Curitiba 10
Denver 10
Manchester 10
Quezon City 10
Brussels 9
Guangzhou 9
Memphis 9
Tel Aviv 9
Thái Nguyên 9
Ankara 8
Istanbul 8
Melito di Napoli 8
Mumbai 8
Nha Trang 8
Paris 8
Riyadh 8
San José 8
Tân Tiến 8
Tây Ninh 8
Totale 8.836
Salva come PNG Salva come JPEG
Nome #
A functional 3D full-thickness model for comprehending the interaction between airway epithelium and connective tissue in cystic fibrosis 219
3-(2-Benzyloxyphenyl)isoxazoles and isoxazolines: synthesis and evaluation as CFTR activators 203
Light-responsive microRNA miR-211 targets Ezrin to modulate lysosomal biogenesis and retinal cell clearance 185
A chloride conductance evoked by hypotonic shock in epithelial cells 154
Assessing the Potential of N-Butyl-l-deoxynojirimycin (l-NBDNJ) in Models of Cystic Fibrosis as a Promising Antibacterial Agent 150
Pharmacological potentiators of the calcium signaling cascade identified by high-throughput screening 149
Analysis of inhibitors of the anoctamin-1 chloride channel (transmembrane member 16A, TMEM16A) reveals indirect mechanisms involving alterations in calcium signalling 139
The role of functional studies in the diagnosis and treatment of Cystic Fibrosis: comparing the case of the G970D and G970R mutation. 137
Rheological Properties of Cystic Fibrosis Bronchial Secretion and in Vitro Drug Permeation Study: The Effect of Sodium Bicarbonate 134
Airway surface hyperviscosity and defective mucociliary transport by IL-17/TNF-α are corrected by beta-adrenergic stimulus 132
Pharmacoproteomics pinpoints HSP70 interaction for correction of the most frequent Wilson disease-causing mutant of ATP7B 131
Functional restoration of a CFTR splicing mutation through RNA delivery of CRISPR adenine base editor 129
Ionocytes and CFTR Chloride Channel Expression in Normal and Cystic Fibrosis Nasal and Bronchial Epithelial Cells 126
Targeting ion channels in cystic fibrosis 124
Development of the olfactory epithelium and Nasal Glands in TMEM16A-/-and TMEM16A+/ +Mice 123
High-throughput screening for modulators of ACVR1 transcription: Discovery of potential therapeutics for fibrodysplasia ossificans progressiva 122
Distinct Responses of Cystic Fibrosis Epithelial Cells to SARS-CoV-2 and Influenza A Virus 120
Unravelling druggable signalling networks that control F508del-CFTR proteostasis 120
High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel 120
Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel 118
Upregulation of TMEM16A protein in bronchial epithelial cells by bacterial pyocyanin 117
Two CFTR mutations within codon 970 differently impact on the chloride channel functionality 116
The ubiquitin ligase tripartite-motif-protein 32 is induced in Duchenne muscular dystrophy 115
The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR 114
Genetic Inhibition of the Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated to F508del Cystic Fibrosis Mutation 114
Covid-19 in cystic fibrosis patients compared to the general population: Severity and virus-host cell interactions 113
Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6) 113
A novel missense mutation in ANO5/TMEM16E is causative for gnathodiaphyseal dyplasia in a large Italian pedigree 113
Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis 111
Functional analysis of acid-activated Cl- channels: Properties and mechanisms of regulation 110
Novel Hits in the Correction of δf508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein: Synthesis, Pharmacological, and ADME Evaluation of Tetrahydropyrido[4,3-d]pyrimidines for the Potential Treatment of Cystic Fibrosis 110
Goblet Cell Hyperplasia Requires High Bicarbonate Transport to Support Mucin Release 109
Altered expression of ano1 variants in human diabetic gastroparesis 109
Effect of inflammatory stimuli on airway ion transport 109
Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms 108
A minimal isoform of the TMEM16A protein associated with chloride channel activity 107
Easy-to-Build and Reusable Microfluidic Device for the Dynamic Culture of Human Bronchial Cystic Fibrosis Epithelia 106
A European regulatory perspective on cystic fibrosis: Current treatments, trends in drug development and translational challenges for CFTR modulators 106
TRPV4 and purinergic receptor signalling pathways are separately linked in airway epithelia to CFTR and TMEM16A chloride channels 106
Phenylhydrazones as Correctors of a Mutant Cystic Fibrosis Transmembrane Conductance Regulator 105
Pharmacological rescue of mutant CFTR protein improves the viscoelastic properties of CF mucus 105
Pharmacological analysis of epithelial chloride secretion mechanisms in adult murine airways 105
Increased expression of ATP12A proton pump in cystic fibrosis airways 104
The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epithelial Model to Address Non-Responders to CFTR-Modulating Drugs 103
Esculentin-1a-derived peptides promote clearance of pseudomonas aeruginosa internalized in bronchial cells of cystic fibrosis patients and lung cell migration: Biochemical properties and a plausible mode of action 103
Partial rescue of f508del-cftr stability and trafficking defects by double corrector treatment 103
Functional rescue of F508del-CFTR through revertant mutations introduced by CRISPR base editing 99
Phenylglycine and sulfonamide correctors of defective ΔF508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating 95
Intrinsic Abnormalities of Cystic Fibrosis Airway Connective Tissue Revealed by an In Vitro 3D Stromal Model 95
Altered channel gating mechanism for CFTR inhibition by a high-affinity thiazolidinone blocker 92
Identification of 6,9-dihydro-5H-pyrrolo[3,2-h]quinazolines as a new class of F508del-CFTR correctors for the treatment of cystic fibrosis 90
The apical mucus layer alters the pharmacological properties of the airway epitheliumy 90
Volume-sensitive chloride currents in four epithelial cell lines are not directly correlated to the expression of the MDR-1 gene 90
Biophysical characteristics of swelling-activated Cl- channels in human tracheal 9HTEo-cells 87
Sodium-Coupled Monocarboxylate Absorption in the Airway Epithelium Is Facilitated by the SLC5A8 Co-Transporter 86
KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse model 86
Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis 85
Airway microenvironment alterations and pathogen growth in cystic fibrosis 84
An overview on chemical structures as ΔF508-CFTR correctors 84
Characterization of the human gene coding for the swelling-dependent chloride channel ICln at position 11q13.5-14.1 (CLNS1A) and further characterization of the chromosome 6 (CLNS1B) localization 82
TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity 82
Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators 82
Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia 82
A large conductance Cl- channel revealed by patch-recordings in human fibroblasts 82
Correction of delF508-CFTR activity with benzo(c)quinolizinium compounds through facilitation of its processing in cystic fibrosis airway cells 81
ATP and A1 adenosine receptor agonists mobilize intracellular calcium and activate K+ and Cl- currents in normal and cystic fibrosis airway epithelial cells 80
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion 80
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia 80
The Autophagy Inhibitor Spautin-1 Antagonizes Rescue of Mutant CFTR Through an Autophagy-Independent and USP13-Mediated Mechanism 79
Volume regulatory taurine release in human tracheal 9HTEo- and multidrug resistant 9HTEo-/Dx cells 79
Lack of Kcnn4 improves mucociliary clearance in muco-obstructive lung disease 79
Why is the cystic fibrosis gene so frequent? 78
Epithelial sodium channel silencing as a strategy to correct the airway surface fluid deficit in cystic fibrosis 77
Regulation of TMEM16A chloride channel properties by alternative splicing 77
Evidence for direct CFTR inhibition by CFTRinh-172 based on Arg347 mutagenesis 77
Antihypertensive 1,4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations 77
Pharmacological rescue of the G85E CFTR variant by preclinical and approved modulators 76
Combination potentiator (‘co-potentiator’) therapy for CF caused by CFTR mutants, including N1303K, that are poorly responsive to single potentiators 76
α-aminoazaheterocyclic-methylglyoxal adducts do not inhibit cystic fibrosis transmembrane conductance regulator chloride channel activity 76
Activation of Ca(2+)-dependent K+ and Cl- currents by UTP and ATP in CFPAC-1 cells 76
Normal calcium-activated anion secretion in a mouse selectively lacking TMEM16A in intestinal epithelium 76
Substituted 2-Acylaminocycloalkylthiophene-3-carboxylic Acid Arylamides as Inhibitors of the Calcium-Activated Chloride Channel Transmembrane Protein 16A (TMEM16A) 75
Lectin Conjugates as Potent, Nonabsorbable CFTR Inhibitors for Reducing Intestinal Fluid Secretion in Cholera 75
Activation of G551D CFTR channel with MPB-91: regulation by ATPase activity and phosphorylation 75
A class of non-selective cation channels in human fibroblasts 75
The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels 74
Synthesis of 4-thiophen-2′-yl-1,4-dihydropyridines as potentiators of the CFTR chloride channel 74
Influence of cell background on pharmacological rescue of mutant CFTR 74
Anoctamin pharmacology 73
DOG1 regulates growth and IGFBP5 in gastrointestinal stromal tumors 73
IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro 73
Author Correction: Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis (Scientific Reports, (2019), 9, 1, (6516), 10.1038/s41598-019-42751-4) 73
Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation 72
Regulation of taurine transport in murine macrophages 72
TMEM16A (ANO1) as a therapeutic target in cystic fibrosis 71
Alternative splicing at a NAGNAG acceptor site as a novel phenotype modifier 71
CFTR chloride channel drug discovery--inhibitors as antidiarrheals and activators for therapy of cystic fibrosis 71
ANO4 (Anoctamin 4) Is a Novel Marker of Zona Glomerulosa That Regulates Stimulated Aldosterone Secretion 71
Modulation of HLA-DR antigen and ICAM-1 molecule expression on airway epithelial cells by sodium nedocromil 70
Speeding up the identification of cystic fibrosis transmembrane conductance regulator-targeted drugs: An approach based on bioinformatics strategies and surface plasmon resonance 70
Totale 9.948
Salva come PNG Salva come JPEG
Categoria #
all - tutte 54.277
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 54.277
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022554 0 0 2 8 30 28 4 23 20 7 57 375
2022/20231.300 176 48 12 129 140 152 12 154 224 122 110 21
2023/2024723 36 145 116 73 34 48 27 32 6 6 128 72
2024/20253.782 235 263 20 23 42 312 448 231 407 380 1.110 311
2025/20267.507 798 611 784 508 1.092 264 772 623 1.230 352 234 239
2026/20271.143 271 339 533 0 0 0 0 0 0 0 0 0
Totale 15.763