Malignant mesothelioma is a uniformly fatal cancer of the pleural and peritoneal spaces. Several challenging clinical problems include poor understanding of the pathophysiology, inaccurate diagnosis from tissue samples, and unsuccessful treatment strategies. The purpose of this study was to use immunocytochemistry analysis to identify specific markers in mesothelioma compared with normal mesothelium. Design: We performed analysis on effusion and mesothelioma tissue specimens from 23 patients and compared these to 4 control pleural tissue samples using cytoimmunochemistry. In conclusion our data demonstrated altered localitation and expression of galectin-3 in mesothelioma.
Galectin-3 expression in benign an malignant mesothelial cells / Esposito, F; Griffo, SALVATORE G. PPE ROMANO; Boschi, Rosalba; D'Armiento, FRANCESCO PAOLO; Vetrani, Antonio. - STAMPA. - 98:(2006), pp. 406-407. (Intervento presentato al convegno 32°Euoropean Congress of Cytologyu tenutosi a Venice nel 1-4 ottobre).
Galectin-3 expression in benign an malignant mesothelial cells
GRIFFO, SALVATORE G.PPE ROMANO;BOSCHI, ROSALBA;D'ARMIENTO, FRANCESCO PAOLO;VETRANI, ANTONIO
2006
Abstract
Malignant mesothelioma is a uniformly fatal cancer of the pleural and peritoneal spaces. Several challenging clinical problems include poor understanding of the pathophysiology, inaccurate diagnosis from tissue samples, and unsuccessful treatment strategies. The purpose of this study was to use immunocytochemistry analysis to identify specific markers in mesothelioma compared with normal mesothelium. Design: We performed analysis on effusion and mesothelioma tissue specimens from 23 patients and compared these to 4 control pleural tissue samples using cytoimmunochemistry. In conclusion our data demonstrated altered localitation and expression of galectin-3 in mesothelioma.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
