We here describe the synthesis of a series of novel bicyclic ribonucleoside derivatives, with 18-crown-6 ether moieties attached via their ribose 2- and 3-positions, as first examples of crown ether ring-fused nucleosides, to be evaluated as antiviral and/or antitumoral agents.
Crown ether ring-fused nucleosides: synthesis and conformational properties / C., Coppola; J., D’Onofrio; DE NAPOLI, Lorenzo; DI FABIO, Giovanni; Montesarchio, Daniela. - In: NUCLEIC ACIDS SYMPOSIUM SERIES. - ISSN 1746-8272. - STAMPA. - 52:(2008), pp. 667-668. (Intervento presentato al convegno 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids tenutosi a Kyoto (Giappone) nel 8-12 settembre 2008) [10.1093/nass/nrn337].
Crown ether ring-fused nucleosides: synthesis and conformational properties
DE NAPOLI, LORENZO;DI FABIO, GIOVANNI;MONTESARCHIO, DANIELA
2008
Abstract
We here describe the synthesis of a series of novel bicyclic ribonucleoside derivatives, with 18-crown-6 ether moieties attached via their ribose 2- and 3-positions, as first examples of crown ether ring-fused nucleosides, to be evaluated as antiviral and/or antitumoral agents.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
