This symposium report describes the designing of an a-helical dimer, covalently linked in a parallel or antiparallel orientation, that specifically interacts with only one of the target enzymes recognized by calmodulin (CaM). The chosen protein sequence was from the CaM binding domain of calcineurin.
A Novel Class of Calmodulin Mimetics: De Novo Designed Proteins in Molecular Recognition / Lombardi, Angelina; G., Ghirlanda; L., Zaccaro; Pavone, Vincenzo; W. F., Degrado. - STAMPA. - (1999), pp. 94-96.
A Novel Class of Calmodulin Mimetics: De Novo Designed Proteins in Molecular Recognition
LOMBARDI, ANGELINA;PAVONE, VINCENZO;
1999
Abstract
This symposium report describes the designing of an a-helical dimer, covalently linked in a parallel or antiparallel orientation, that specifically interacts with only one of the target enzymes recognized by calmodulin (CaM). The chosen protein sequence was from the CaM binding domain of calcineurin.File in questo prodotto:
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