The present invention describes compounds of formula (I), and in particular the 7- nitro-5-phenyl-1 -(pyrrolidin-1 - ylmethyl)-1 H-benzo[e][1,4]diazepin-2(3H)-one compound and their pharmaceuticall acceptable salts. The compounds of the invention are useful for medical use, particularly as active ingredient potentially useful for the treatment of cerebral ischemia and other disease characterized by deregulation of sodium and calcium homeostasis
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives / Pignataro, Giuseppe; Annunziato, Lucio; Molinaro, Pasquale; Scorziello, Antonella; Secondo, Agnese; Pannaccione, Anna; Cuomo, Ornella; Cantile, Maria; DI RENZO, GIANFRANCO MARIA LUIGI; Caliendo, Giuseppe; Santagada, Vincenzo; Severino, Beatrice; Fiorino, Ferdinando. - (2012).
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives
PIGNATARO, GIUSEPPE;ANNUNZIATO, LUCIO;MOLINARO, PASQUALE;SCORZIELLO, ANTONELLA;SECONDO, AGNESE;PANNACCIONE, ANNA;CUOMO, ORNELLA;CANTILE, MARIA;DI RENZO, GIANFRANCO MARIA LUIGI;CALIENDO, GIUSEPPE;SANTAGADA, VINCENZO;SEVERINO, BEATRICE;FIORINO, FERDINANDO
2012
Abstract
The present invention describes compounds of formula (I), and in particular the 7- nitro-5-phenyl-1 -(pyrrolidin-1 - ylmethyl)-1 H-benzo[e][1,4]diazepin-2(3H)-one compound and their pharmaceuticall acceptable salts. The compounds of the invention are useful for medical use, particularly as active ingredient potentially useful for the treatment of cerebral ischemia and other disease characterized by deregulation of sodium and calcium homeostasisI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
