The exogenous delivery of erythropoietin (EPO) and EPO derivatives (EPO-Ds) represents a valuable strategy to protect the retina from degeneration. In this chapter we describe a method to deliver EPO and the EPO derivative S100E in the light-damage model of induced retinal degeneration using adeno-associated viral (AAV) vectors and to evaluate the functional and morphological protection of the retina from light damage.
Photoreceptor degeneration in mice: adeno-associated viral vector-mediated delivery of erythropoietin / Colella, P; Auricchio, Alberto. - 982:(2013). [10.1007/978-1-62703-308-4_16]
Photoreceptor degeneration in mice: adeno-associated viral vector-mediated delivery of erythropoietin.
AURICCHIO, ALBERTO
2013
Abstract
The exogenous delivery of erythropoietin (EPO) and EPO derivatives (EPO-Ds) represents a valuable strategy to protect the retina from degeneration. In this chapter we describe a method to deliver EPO and the EPO derivative S100E in the light-damage model of induced retinal degeneration using adeno-associated viral (AAV) vectors and to evaluate the functional and morphological protection of the retina from light damage.File in questo prodotto:
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