Cardiotoxicity is one of the most significant adverse effects of the oncologic treatment with doxorubicin, which is responsible for a substantial morbid and mortality. Small molecules derived from medicinal plants with anti-inflammatory properties could have cardioprotective activites so potentially used in cardio-oncology management. Nanomedicine offer a new pharmacological tool able to increase bioavailability and protect natural bioactives with antiinflammatory and cardioprotective action.
P616Cardioprotective effects of nanoemulsions loaded with natural anti-inflammatory molecules against doxorubicin-induced cardiotoxicity in cardiomyocytes / Maurea, N; Quagliariello, V; Vecchione, R; Di Cicco, C; De Capua, A; Coppola, C; Piscopo, G; Paciello, R; Iaffaioli, Rv; Netti, Pa; Botti, G. - In: EUROPEAN HEART JOURNAL. - ISSN 0195-668X. - 39:suppl_1(2018). [10.1093/eurheartj/ehy564.P616]
P616Cardioprotective effects of nanoemulsions loaded with natural anti-inflammatory molecules against doxorubicin-induced cardiotoxicity in cardiomyocytes
Netti PA;Botti G
2018
Abstract
Cardiotoxicity is one of the most significant adverse effects of the oncologic treatment with doxorubicin, which is responsible for a substantial morbid and mortality. Small molecules derived from medicinal plants with anti-inflammatory properties could have cardioprotective activites so potentially used in cardio-oncology management. Nanomedicine offer a new pharmacological tool able to increase bioavailability and protect natural bioactives with antiinflammatory and cardioprotective action.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
