In this paper, different nanostructured semiconductors with advanced properties are explored for the realization of both optical and electrical biosensors for DNA detection. A hybrid sensor constituted by graphene oxide (GO) covalently grafted on a porous silicon (PSi) matrix is realized. A peptide nucleic acid (PNA) probe, able to recognize its complementary DNA (c-DNA) sequence, is immobilized on the surface of PSi/GO device for label-free optical sensing. Electrical sensing of DNA is also demonstrated using a Zinc Oxide Nanowires (ZnONWs) sensor functionalized with PNA probe; the I–V characteristic of the device depends on the c-DNA concentration under analysis.
Hybrid Organic/Inorganic Nanomaterials for Biochemical Sensing / Rea, Ilaria; Dardano, Principia; Moretta, Rosalba; Schiattarella, Chiara; Terracciano, Monica; Casalino, Maurizio; Gioffrè, Mariano; Crisci, Teresa; Chianese, Giovanna; Tramontano, Chiara; Borbone, Nicola; De Stefano, Luca. - 753:(2021), pp. 93-99. (Intervento presentato al convegno AISEM 2020 Annual Conference on Sensors and Microsystems) [10.1007/978-3-030-69551-4_13].
Hybrid Organic/Inorganic Nanomaterials for Biochemical Sensing
Rea, Ilaria
;Dardano, Principia;Moretta, Rosalba;Schiattarella, Chiara;Terracciano, Monica;Crisci, Teresa;Chianese, Giovanna;Tramontano, Chiara;Borbone, Nicola;
2021
Abstract
In this paper, different nanostructured semiconductors with advanced properties are explored for the realization of both optical and electrical biosensors for DNA detection. A hybrid sensor constituted by graphene oxide (GO) covalently grafted on a porous silicon (PSi) matrix is realized. A peptide nucleic acid (PNA) probe, able to recognize its complementary DNA (c-DNA) sequence, is immobilized on the surface of PSi/GO device for label-free optical sensing. Electrical sensing of DNA is also demonstrated using a Zinc Oxide Nanowires (ZnONWs) sensor functionalized with PNA probe; the I–V characteristic of the device depends on the c-DNA concentration under analysis.| File | Dimensione | Formato | |
|---|---|---|---|
|
Rea2021_Chapter_HybridOrganicInorganicNanomate.pdf
solo utenti autorizzati
Descrizione: Articolo principale
Tipologia:
Versione Editoriale (PDF)
Licenza:
Accesso privato/ristretto
Dimensione
366.34 kB
Formato
Adobe PDF
|
366.34 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
