Cell senescence is critical in diverse aspects of organism life. It represents a physiological program to arrest proliferation of damaged/harmful cells and is now considered an important contributor in aging and age-related pathologies. Non-coding RNAs are endogenous transcripts that govern gene regulatory networks impacting both physiological and pathological events. Among them, microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and more recently circular RNAs (circRNAs) are considered crucial regulators of almost all cellular processes, including responses evoked by oxidative stress, such as senescence.
MiRNAs/lncRNAs/circRNAs in Redox Control of Cell Senescence / Faraonio, R.; Punziano, C.; Lettieri-Barbato, D.; Minopoli, G.; &, ; Aquilano, K.. - In: ENCYCLOPEDIA. - ISSN 2673-8392. - (2022).
MiRNAs/lncRNAs/circRNAs in Redox Control of Cell Senescence
Faraonio R.;Punziano C.;Minopoli G.;
2022
Abstract
Cell senescence is critical in diverse aspects of organism life. It represents a physiological program to arrest proliferation of damaged/harmful cells and is now considered an important contributor in aging and age-related pathologies. Non-coding RNAs are endogenous transcripts that govern gene regulatory networks impacting both physiological and pathological events. Among them, microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and more recently circular RNAs (circRNAs) are considered crucial regulators of almost all cellular processes, including responses evoked by oxidative stress, such as senescence.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.