Breast cancer is one of the most common tumors worldwide featured by heterogeneity. The expression of hormone receptors marks different breast cancer subtypes. Each type is pharmacologically treated by using molecules targeting hormone receptors, but this frequently drives chemoresistance. For this reason, the possibility to replicate this hostile human pathology in vitro represents an urgent need to understand the biological basis behind heterogeneity and chemoresistance and explore the efficiency of pharmacological treatments.
An engineered breast cancer model on chip for personalized and multiple drug therapy / Imparato, G.; Mazio, C.; Urciuolo, F.; Netti, P. A.. - (2023). (Intervento presentato al convegno 8th National Congress of Bioengineering, GNB 2023 tenutosi a ita nel 2023).
An engineered breast cancer model on chip for personalized and multiple drug therapy
Imparato G.;Mazio C.;Urciuolo F.;Netti P. A.
2023
Abstract
Breast cancer is one of the most common tumors worldwide featured by heterogeneity. The expression of hormone receptors marks different breast cancer subtypes. Each type is pharmacologically treated by using molecules targeting hormone receptors, but this frequently drives chemoresistance. For this reason, the possibility to replicate this hostile human pathology in vitro represents an urgent need to understand the biological basis behind heterogeneity and chemoresistance and explore the efficiency of pharmacological treatments.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
