The extracellular matrix plays a crucial role in the regulation of tissues and organ functions under both physiologic and pathologic conditions. In our body, each organ is provided with a site-specific ECM presenting to the cells the instructive molecular signals triggering and guiding organ-specific biological processes. Here we report a bioengineering method to obtain scaffold-free organotypic tissues composed of an endogenous and site-specific connective microenvironment.
Bio-fabrication of in vitro tissues possessing organ-specific endogenous extracellular matrices / Urciuolo, F.; Imparato, G.; De Gregorio, V.; Casale, C.; Netti, P. A.. - (2023). (Intervento presentato al convegno 8th National Congress of Bioengineering, GNB 2023 tenutosi a ita nel 2023).
Bio-fabrication of in vitro tissues possessing organ-specific endogenous extracellular matrices
Urciuolo F.;De Gregorio V.;Casale C.;Netti P. A.
2023
Abstract
The extracellular matrix plays a crucial role in the regulation of tissues and organ functions under both physiologic and pathologic conditions. In our body, each organ is provided with a site-specific ECM presenting to the cells the instructive molecular signals triggering and guiding organ-specific biological processes. Here we report a bioengineering method to obtain scaffold-free organotypic tissues composed of an endogenous and site-specific connective microenvironment.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
