Adrenergic receptors (AR) are essential regulators of vascular physiology and are largely used as pharmacological targets. This chapter will review the main roles of the vascular AR in both the endothelium and vascular smooth muscle. We will discuss the ability of ARs to regulate key functions in endothelial and smooth muscle cells and their involvement in several pathologic conditions such as hypertension, atherosclerosis, and heart failure.
Adrenergic receptors in endothelial and vascular smooth muscle cells / Gambardella, J.; Fiordelisi, A.; Avvisato, R.; Buonaiuto, A.; Cerasuolo, F. A.; Sorriento, D.; Iaccarino, G.. - In: CURRENT OPINION IN PHYSIOLOGY. - ISSN 2468-8673. - 36:(2023). [10.1016/j.cophys.2023.100721]
Adrenergic receptors in endothelial and vascular smooth muscle cells
Gambardella J.;Fiordelisi A.;Avvisato R.;Buonaiuto A.;Cerasuolo F. A.;Sorriento D.;Iaccarino G.
2023
Abstract
Adrenergic receptors (AR) are essential regulators of vascular physiology and are largely used as pharmacological targets. This chapter will review the main roles of the vascular AR in both the endothelium and vascular smooth muscle. We will discuss the ability of ARs to regulate key functions in endothelial and smooth muscle cells and their involvement in several pathologic conditions such as hypertension, atherosclerosis, and heart failure.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
