IRIS
ORIENTE, FRANCESCO
 Distribuzione geografica
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Continente #
AS - Asia 3.445
NA - Nord America 3.389
EU - Europa 2.482
SA - Sud America 436
AF - Africa 81
OC - Oceania 4
Totale 9.837
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Nazione #
US - Stati Uniti d'America 3.239
SG - Singapore 1.581
RU - Federazione Russa 1.192
CN - Cina 699
VN - Vietnam 618
IT - Italia 363
BR - Brasile 356
HK - Hong Kong 242
DE - Germania 179
FR - Francia 142
FI - Finlandia 116
NL - Olanda 100
CA - Canada 96
GB - Regno Unito 86
IE - Irlanda 84
UA - Ucraina 73
IN - India 62
SE - Svezia 52
JP - Giappone 47
AR - Argentina 33
PL - Polonia 32
BD - Bangladesh 28
ZA - Sudafrica 27
MX - Messico 26
IQ - Iraq 19
PH - Filippine 19
KR - Corea 16
CI - Costa d'Avorio 14
TR - Turchia 14
EC - Ecuador 13
PK - Pakistan 13
TH - Thailandia 12
CO - Colombia 11
ID - Indonesia 11
AT - Austria 9
ES - Italia 9
LT - Lituania 9
UZ - Uzbekistan 9
EG - Egitto 8
MA - Marocco 8
CL - Cile 7
JM - Giamaica 7
JO - Giordania 7
SA - Arabia Saudita 7
VE - Venezuela 7
AE - Emirati Arabi Uniti 5
TW - Taiwan 5
DO - Repubblica Dominicana 4
DZ - Algeria 4
EE - Estonia 4
IL - Israele 4
KG - Kirghizistan 4
NI - Nicaragua 4
PY - Paraguay 4
TN - Tunisia 4
AL - Albania 3
BE - Belgio 3
BG - Bulgaria 3
KZ - Kazakistan 3
LB - Libano 3
LV - Lettonia 3
NP - Nepal 3
PE - Perù 3
PT - Portogallo 3
SN - Senegal 3
SY - Repubblica araba siriana 3
AU - Australia 2
AZ - Azerbaigian 2
CZ - Repubblica Ceca 2
ET - Etiopia 2
HN - Honduras 2
IS - Islanda 2
LC - Santa Lucia 2
MY - Malesia 2
NG - Nigeria 2
PA - Panama 2
RO - Romania 2
RS - Serbia 2
UY - Uruguay 2
BB - Barbados 1
BS - Bahamas 1
BY - Bielorussia 1
CH - Svizzera 1
CR - Costa Rica 1
DK - Danimarca 1
GA - Gabon 1
GE - Georgia 1
GP - Guadalupe 1
HR - Croazia 1
HT - Haiti 1
IR - Iran 1
KE - Kenya 1
LA - Repubblica Popolare Democratica del Laos 1
LU - Lussemburgo 1
MD - Moldavia 1
ML - Mali 1
MN - Mongolia 1
MR - Mauritania 1
MT - Malta 1
MU - Mauritius 1
Totale 9.824
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Città #
Singapore 731
San Jose 551
Ashburn 297
Chandler 264
Moscow 247
Hong Kong 233
Beijing 223
Ho Chi Minh City 180
Hanoi 135
Santa Clara 133
The Dalles 130
Lauterbourg 84
Los Angeles 83
Amsterdam 80
Boston 78
Millbury 76
Princeton 76
Jacksonville 75
Munich 71
Naples 63
Nanjing 56
Napoli 49
New York 47
Ottawa 46
Buffalo 45
Hefei 45
Dallas 44
Tokyo 34
São Paulo 32
Council Bluffs 31
Seattle 31
Wilmington 31
Da Nang 28
Redondo Beach 27
Turku 27
Haiphong 25
Houston 24
Orem 23
Frankfurt am Main 21
Pune 21
London 20
Warsaw 20
Brooklyn 19
Atlanta 18
Des Moines 18
Chennai 17
Nanchang 17
Toronto 17
Hebei 16
Montreal 16
Denver 15
Helsinki 14
Shenyang 14
Johannesburg 13
Lawrence 13
Mexico City 13
Tianjin 13
Washington 13
Biên Hòa 12
Manchester 12
Rome 12
Boardman 10
Guangzhou 10
Phoenix 10
Poplar 10
San Francisco 10
Changsha 9
Hangzhou 9
Jiaxing 9
Kunming 9
Paris 9
Stockholm 9
Thái Nguyên 9
Chicago 8
Curitiba 8
Falls Church 8
Kronberg 8
Norwalk 8
Augusta 7
Can Tho 7
Falkenstein 7
Hải Dương 7
Quito 7
Secaucus 7
Tashkent 7
Woodbridge 7
Amman 6
Ankara 6
Baghdad 6
Bangkok 6
Caserta 6
Miami 6
Mumbai 6
New Delhi 6
Salt Lake City 6
Seoul 6
Thái Bình 6
Wroclaw 6
Brasília 5
Bình Phước 5
Totale 5.110
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Nome #
Prep1 Deficiency Affects Olfactory Perception and Feeding Behavior by Impairing BDNF-TrkB Mediated Neurotrophic Signaling 175
Glucose-induced expression of the homeotic transcription factor Prep1 is associated with histone post-translational modifications in skeletal muscle 173
A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells 161
Phorbol esters induce intracellular accumulation of the anti-apoptotic protein PED/PEA-15 by preventing ubiquitinylation and proteasomal degradation. 159
Low-Dose bisphenol-A impairs adipogenesis and generates dysfunctional 3T3-L1 adipocytes 159
Prep1 regulates angiogenesis through a PGC-1α-mediated mechanism 159
Glucose regulates diacylglycerol intracellular levels and protein kinase C activity by modulating diacylglycerol-kinase subcellular localization. 158
Low Dose Bisphenol-A Regulates Inflammatory Cytokines through GPR30 in Mammary Adipose Cells 157
Peroxisome Proliferator-Activated Receptor γ activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 expression in skeletal muscle cells. Evidence for involvement of Activator Protein-1. 157
Potential Mechanisms of Bisphenol A (BPA) Contributing to Human Disease 155
Abnormal glucose transport and GLUT1 cell-surface content in fibroblasts and skeletal muscle from NIDDM and obese subjects 154
Prep1, A Homeodomain transcription factor involved in glucose and lipid metabolism 154
Marine-Derived Phosphoeleganin and Its Semisynthetic Derivative Decrease IL6 Levels and Improve Insulin Signaling in Human Hepatocellular Carcinoma Cells 151
miR-214-dependent increase of PHLPP2 levels mediates the impairment of insulin-stimulated akt activation in mouse aortic endothelial cells exposed to methylglyoxal 149
Zoonotic Risk of Encephalitozoon cuniculi in Animal-Assisted Interventions: Laboratory Strategies for the Diagnosis of Infections in Humans and Animals 149
Autophagy and NLRP3 inflammasome crosstalk in neuroinflammation in aged bovine brains 148
In L6 cells, glucose induces cytosolic translocation of PKC alpha, trans-activates the insulin receptor kinase and regulates its own uptake 144
The Relevance of Insulin Action in the Dopaminergic System 142
PED/PEA-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells 140
Bisphenol-A Impairs Insulin Action and Up-Regulates Inflammatory Pathways in Human Subcutaneous Adipocytes and 3T3-L1 Cells. 139
In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routing 138
Diagnosis of Flier’s syndrome in a patient with nondiabetic hypoglycemia: a case report and critical appraisal of the literature 137
Prep1 deficiency improves metabolic response in white adipose tissue 134
Interleukin 6 reduces vascular smooth muscle cell apoptosis via Prep1 and is associated with aging 132
SARS-CoV-2 Affects Both Humans and Animals: What Is the Potential Transmission Risk? A Literature Review 130
Phosphorylation and Signalling of the Insulin Receptor are Controlled by a Basic AminoAcid Motif. 130
PED/PEA-15 controls fibroblast motility and wound closure by ERK1/2-dependent mechanisms 129
Anti-skeletal muscle antibodies in sera of dogs with leishmaniasis. 129
Implication of the nlrp3 inflammasome in bovine age‐related sarcopenia 125
PDK1 interaction with insulin receptor and tyrosine phosphorylation are required for insulin metabolic action. 124
Insulin induces the interaction of IRS-1 with PKC-alpha and 14-3-3-epsilon 123
Insulin-activated protein kinase Cbeta bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells 121
Low-dose bisphenol-a promotes epigenetic changes at pparγ promoter in adipose precursor cells 121
Resveratrol Improves Endothelial Function by A PREP1-Mediated Pathway in Mouse Aortic Endothelial Cells 120
Platelet-rich plasma counteracts detrimental effect of high-glucose concentrations on mesenchymal stem cells from Bichat fat pad 119
Cytokine signature and COVID-19 prediction models in the two waves of pandemics 119
Insulin receptor internalization and intracellular sorting are regulated by protein kinase C-zeta and protein kinase b/Akt. 118
Leishmania spp.-infected dogs have circulating anti-skeletal muscle autoantibodies recognizing serca1 118
Thiazolidinediones control the expression of Ped/Pea-15 (phosphoprotein enriched in diabetes) both in vitro and in vivo 117
Thiazolidinediones control the expression of phosphoprotein enriched in diabetes (ped/pea-15) both in vitro and in vivo 110
In L6 skeletal muscle tells advanced glycation end products inhibit insulin action by activating src and inducing the formation of a multi-molecular complex 110
Substrate-zymography: a still worthwhile method for gelatinases analysis in biological samples 110
Insulin-activated PKCb bypasses Ras and stimulates MAPKinase activity and cell proliferation in muscle cells 109
PREP1 deficiency downregulates hepatic lipogenesis and attenuates steatohepatitis in mice. 109
Differential role of IRS-1 and IRS-2 in L6 muscle cells expressing the ARG(1152)-> GLN insulin receptor. 108
Insulin stimulates phosphoinositides-dependent kinase (PDK)-1 binding to insulin-receptor C-terminus followed by tyrosine-phosphorylation and activation. 108
Cultured beta cells PED overexpression alters intracellular calcium levels thereby impairing glucose induced insulin secretion 105
Thrombin-activated platelets enhance healing of ulcerative skin lesion by inducing IGF-1 release by skin fibroblasts 104
Differential role of insulin receptor substrate (IRS1 and IRS) in L6 skeletal muscle cells expressing the Arg1152Gln insulin receptor. 103
PED/PEA-15 controls TGFbeta production and fibronectin secretion through a PLD/PKCbeta pathway 101
TGF beta impairs muscle differentiation and induces autophagy by PED/PEA-15-mediated pathway 99
In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routine. 98
Antagonism between Hepatocyte Nuclear Factor 4 alpha (HNF4 alpha) and Chicken Ovalbumin Upstream Promoter-Transcription Factor 2 (COUP-TFII) modulates Ped/Pea-15 gene expression 98
Thrombin-activated platelets induce proliferation of human skin fibroblasts by stimulating autocrine production of insulin-like growth factor-1 96
Ped/pea-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells 96
Dolichol reverts lovastatin-induced inhibition of insulin action on glycogen synthesis but not on cell cycle regulation, in skeletal muscle and liver cells 95
Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of PED/PEA-15 gene 92
Glucose-transport Is Genetically Altered In Subjects With Type-ii Diabetes (niddm) 91
Glucose regulates insulin mitogenic effect by modulating SHP-2 activation and localization in JAr cells. 90
In skeletal muscle, advanced glycation end products inhibit insulin action and induce the formation of multimolecular complexes including the receptor for AGEs. 90
Glucose regulates insulin mitogenic effect by modulating SHP-2 activation and localization in JAr cells. 89
Insulin receptor substrate-2 phosphorylation is necessary for protein kinase czeta activation by insulin in l6hir cells. 87
Transforming growth factor-beta increases the expression of PED/PEA-15 and glucose uptake via smad-3 phosphorylation in l6 cells 87
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction 86
The PED/PEA-15 diabetogene as a potential thiazolidinedione target 85
Prep1 controls insulin glucoregulatory function in liver by transcriptional targetting of SHP1 tyrosine phosphatase. 85
Receptor-mediated internalization of insulin: potential role of pp120/HA4, a substrate of the insulin receptor kinase 84
Differential role of insulin receptor substrate (IRS)-1 and IRS-2 in L6 skeletal muscle cells expressing the Arg1152 --> Gln insulin receptor. 84
The function of PED, a novel gene in type 2 diabetes 84
Prep1 Controls Insulin Glucoregulatory Function in Liver by Transcriptional Targetting of SHP1 Tyrosine Phosphatase 82
In skeletal muscle cells advanced glycation end products inhibit insulin action by inducing the formation of a multi-molecular complex which includes RAGE, PKCalpha and IRS1 79
The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes 77
Human glycated albumin affects glucose metabolism in L6 skeletal muscle cells by impairing insulin-induced insulin receptor substrate (IRS) signaling through a protein kinase C alpha-mediated mechanism 75
Overproduction of phosphoprotein enriched in diabetes (PED) induces mesangial expansion and upregulates protein kinase C-beta activity and TGF-beta1 expression. 72
Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase. 71
EVOO Polyphenols Exert Anti-Inflammatory Effects on the Microglia Cell through TREM2 Signaling Pathway 70
Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism. 70
Glucose regulates insulin mitogenic effect by modulating SHP-2 activation and localization in JAr cells 70
Activation and mitochondrial translocation of protein kinase Cdelta are necessary for insulin stimulation of pyruvate dehydrogenase complex activity in muscle and liver cells 70
Platelet - Rich Plasma Increases Growth and Motility of Adipose Tissue - Derived Mesenchymal Stem Cells and Controls Adipocyte Secretory Function 69
Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling 67
PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis 65
Protein kinase C-alpha regulates insulin action and degradation by interacting with insulin receptor substrate-1 and 14-3-3 epsilon. 65
In L6 skeletal muscle cells, glucose induces cytosolic translocation of Protein Kinase C-alfa and trans-activates the insulin receptor kinase. 64
Mouse models of insulin resistance 62
Overexpression of the ped/pea-15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin action 62
Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15 61
Protein kinase C-zeta and protein kinase B regulate distinct steps of insulin endocytosis and intracellular sorting 60
Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase 59
In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routing 59
Protein Kinase B/Akt Binds and Phosphorylates PED/PEA-15, Stabilizing Its Antiapoptotic Action 59
Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development 58
PED/PEA-15 induces autophagy and mediates TGF-beta1 effect on muscle cell differentiation. 57
Protein kinase C (PKC)-alpha activation inhibits PKC-zeta and mediates the action of PED/PEA-15 on glucose transport in the L6 skeletal muscle cells 54
The IR1152 mutant insulin receptor selectively impairs insulin action in skeletal muscle but not in liver 50
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Totale 10.097
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Categoria #
all - tutte 33.910
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.910
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022564 5 0 9 4 12 18 12 16 89 36 145 218
2022/2023591 96 61 25 25 74 74 3 40 87 68 26 12
2023/2024427 12 56 34 26 36 75 6 58 8 10 75 31
2024/20252.558 141 121 21 37 91 112 265 132 137 278 980 243
2025/20264.990 550 304 520 524 891 230 647 260 514 358 110 82
2026/202751 51 0 0 0 0 0 0 0 0 0 0 0
Totale 10.097