IRIS
ORIENTE, FRANCESCO
 Distribuzione geografica
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Continente #
NA - Nord America 1.545
EU - Europa 805
AS - Asia 771
AF - Africa 13
SA - Sud America 8
OC - Oceania 1
Totale 3.143
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Nazione #
US - Stati Uniti d'America 1.490
SG - Singapore 336
IT - Italia 255
CN - Cina 239
HK - Hong Kong 164
IE - Irlanda 84
FI - Finlandia 82
RU - Federazione Russa 82
NL - Olanda 78
DE - Germania 72
CA - Canada 54
UA - Ucraina 54
SE - Svezia 40
GB - Regno Unito 28
IN - India 19
CI - Costa d'Avorio 12
FR - Francia 10
BR - Brasile 8
JP - Giappone 7
PL - Polonia 6
TR - Turchia 4
BE - Belgio 3
BG - Bulgaria 3
LT - Lituania 3
AT - Austria 2
AE - Emirati Arabi Uniti 1
DK - Danimarca 1
EE - Estonia 1
ES - Italia 1
ET - Etiopia 1
MX - Messico 1
NZ - Nuova Zelanda 1
UZ - Uzbekistan 1
Totale 3.143
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Città #
Chandler 264
Singapore 236
Hong Kong 164
Ashburn 113
Santa Clara 108
Millbury 76
Princeton 76
Jacksonville 74
Amsterdam 73
Boston 70
Nanjing 56
Napoli 49
Ottawa 45
Naples 35
Wilmington 30
Beijing 28
Seattle 26
Pune 19
Des Moines 18
Nanchang 17
Hebei 16
Houston 13
Lawrence 13
Shenyang 13
Tianjin 13
Helsinki 12
Boardman 9
Jiaxing 9
Kunming 9
Toronto 9
Falls Church 8
Hangzhou 8
Kronberg 8
Norwalk 8
Falkenstein 7
Washington 7
Woodbridge 7
Changsha 6
Munich 6
Rome 6
Augusta 5
Caserta 5
Dallas 5
Guangzhou 5
Zhengzhou 5
Florence 4
Frankfurt am Main 4
Portici 4
Shanghai 4
Auburn 3
Brussels 3
Changchun 3
Crispano 3
Fairfield 3
Hanover 3
Hicksville 3
Idstein 3
Kagoya 3
London 3
Meppel 3
Ningbo 3
Nocera Superiore 3
Paris 3
Shenzhen 3
Sofia 3
Aversa 2
Casoria 2
Cava de' Tirreni 2
Citta Sant'angelo 2
Dalmine 2
Dinami 2
Dublin 2
Fort Worth 2
Hackney 2
Jinan 2
Los Angeles 2
Maddaloni 2
Natal 2
Osaka 2
Redmond 2
San Mateo 2
San Sebastiano al Vesuvio 2
Scafati 2
Taizhou 2
Addis Ababa 1
Andrelândia 1
Ann Arbor 1
Bari 1
Boydton 1
Brescia 1
Cardito 1
Casandrino 1
Castellammare Di Stabia 1
Cava De' Tirreni 1
Chengdu 1
Chiba 1
Clifton 1
Council Bluffs 1
Curitiba 1
Dubai 1
Totale 1.907
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Nome #
Prep1 Deficiency Affects Olfactory Perception and Feeding Behavior by Impairing BDNF-TrkB Mediated Neurotrophic Signaling 76
Glucose regulates diacylglycerol intracellular levels and protein kinase C activity by modulating diacylglycerol-kinase subcellular localization. 71
Potential Mechanisms of Bisphenol A (BPA) Contributing to Human Disease 70
Phorbol esters induce intracellular accumulation of the anti-apoptotic protein PED/PEA-15 by preventing ubiquitinylation and proteasomal degradation. 62
PED/PEA-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells 61
Low Dose Bisphenol-A Regulates Inflammatory Cytokines through GPR30 in Mammary Adipose Cells 59
Abnormal glucose transport and GLUT1 cell-surface content in fibroblasts and skeletal muscle from NIDDM and obese subjects 54
Glucose-induced expression of the homeotic transcription factor Prep1 is associated with histone post-translational modifications in skeletal muscle 53
Low-Dose bisphenol-A impairs adipogenesis and generates dysfunctional 3T3-L1 adipocytes 53
Prep1, A Homeodomain transcription factor involved in glucose and lipid metabolism 53
Insulin receptor substrate-2 phosphorylation is necessary for protein kinase czeta activation by insulin in l6hir cells. 52
Glucose regulates insulin mitogenic effect by modulating SHP-2 activation and localization in JAr cells. 52
Prep1 deficiency improves metabolic response in white adipose tissue 52
miR-214-dependent increase of PHLPP2 levels mediates the impairment of insulin-stimulated akt activation in mouse aortic endothelial cells exposed to methylglyoxal 52
Prep1 regulates angiogenesis through a PGC-1α-mediated mechanism 52
The Relevance of Insulin Action in the Dopaminergic System 50
Diagnosis of Flier’s syndrome in a patient with nondiabetic hypoglycemia: a case report and critical appraisal of the literature 50
Differential role of insulin receptor substrate (IRS1 and IRS) in L6 skeletal muscle cells expressing the Arg1152Gln insulin receptor. 49
Peroxisome Proliferator-Activated Receptor γ activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 expression in skeletal muscle cells. Evidence for involvement of Activator Protein-1. 49
A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells 48
Autophagy and NLRP3 inflammasome crosstalk in neuroinflammation in aged bovine brains 48
Differential role of insulin receptor substrate (IRS)-1 and IRS-2 in L6 skeletal muscle cells expressing the Arg1152 --> Gln insulin receptor. 46
In L6 cells, glucose induces cytosolic translocation of PKC alpha, trans-activates the insulin receptor kinase and regulates its own uptake 46
Bisphenol-A Impairs Insulin Action and Up-Regulates Inflammatory Pathways in Human Subcutaneous Adipocytes and 3T3-L1 Cells. 46
Insulin-activated PKCb bypasses Ras and stimulates MAPKinase activity and cell proliferation in muscle cells 45
In skeletal muscle, advanced glycation end products inhibit insulin action and induce the formation of multimolecular complexes including the receptor for AGEs. 43
Insulin-activated protein kinase Cbeta bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells 42
Implication of the nlrp3 inflammasome in bovine age‐related sarcopenia 42
Zoonotic Risk of Encephalitozoon cuniculi in Animal-Assisted Interventions: Laboratory Strategies for the Diagnosis of Infections in Humans and Animals 42
Glucose regulates insulin mitogenic effect by modulating SHP-2 activation and localization in JAr cells 41
PED/PEA-15 controls fibroblast motility and wound closure by ERK1/2-dependent mechanisms 41
Interleukin 6 reduces vascular smooth muscle cell apoptosis via Prep1 and is associated with aging 41
Thrombin-activated platelets induce proliferation of human skin fibroblasts by stimulating autocrine production of insulin-like growth factor-1 40
Differential role of IRS-1 and IRS-2 in L6 muscle cells expressing the ARG(1152)-> GLN insulin receptor. 40
Insulin induces the interaction of IRS-1 with PKC-alpha and 14-3-3-epsilon 39
Insulin receptor internalization and intracellular sorting are regulated by protein kinase C-zeta and protein kinase b/Akt. 39
Low-dose bisphenol-a promotes epigenetic changes at pparγ promoter in adipose precursor cells 39
Glucose regulates insulin mitogenic effect by modulating SHP-2 activation and localization in JAr cells. 38
Phosphorylation and Signalling of the Insulin Receptor are Controlled by a Basic AminoAcid Motif. 38
Cytokine signature and COVID-19 prediction models in the two waves of pandemics 38
Activation and mitochondrial translocation of protein kinase Cdelta are necessary for insulin stimulation of pyruvate dehydrogenase complex activity in muscle and liver cells 36
Anti-skeletal muscle antibodies in sera of dogs with leishmaniasis. 36
Human glycated albumin affects glucose metabolism in L6 skeletal muscle cells by impairing insulin-induced insulin receptor substrate (IRS) signaling through a protein kinase C alpha-mediated mechanism 35
Dolichol reverts lovastatin-induced inhibition of insulin action on glycogen synthesis but not on cell cycle regulation, in skeletal muscle and liver cells 35
In L6 skeletal muscle tells advanced glycation end products inhibit insulin action by activating src and inducing the formation of a multi-molecular complex 35
In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routine. 33
Cultured beta cells PED overexpression alters intracellular calcium levels thereby impairing glucose induced insulin secretion 32
SARS-CoV-2 Affects Both Humans and Animals: What Is the Potential Transmission Risk? A Literature Review 31
In L6 skeletal muscle cells, glucose induces cytosolic translocation of Protein Kinase C-alfa and trans-activates the insulin receptor kinase. 31
Glucose-transport Is Genetically Altered In Subjects With Type-ii Diabetes (niddm) 31
In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routing 31
PED/PEA-15 induces autophagy and mediates TGF-beta1 effect on muscle cell differentiation. 30
Protein Kinase B/Akt Binds and Phosphorylates PED/PEA-15, Stabilizing Its Antiapoptotic Action 30
Platelet - Rich Plasma Increases Growth and Motility of Adipose Tissue - Derived Mesenchymal Stem Cells and Controls Adipocyte Secretory Function 30
Platelet-rich plasma counteracts detrimental effect of high-glucose concentrations on mesenchymal stem cells from Bichat fat pad 30
In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routing 29
Substrate-zymography: a still worthwhile method for gelatinases analysis in biological samples 29
Marine-Derived Phosphoeleganin and Its Semisynthetic Derivative Decrease IL6 Levels and Improve Insulin Signaling in Human Hepatocellular Carcinoma Cells 28
Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling 28
Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15 28
Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase 28
PDK1 interaction with insulin receptor and tyrosine phosphorylation are required for insulin metabolic action. 28
Prep1 controls insulin glucoregulatory function in liver by transcriptional targetting of SHP1 tyrosine phosphatase. 28
Leishmania spp.-infected dogs have circulating anti-skeletal muscle autoantibodies recognizing serca1 28
Overproduction of phosphoprotein enriched in diabetes (PED) induces mesangial expansion and upregulates protein kinase C-beta activity and TGF-beta1 expression. 27
Protein kinase C-alpha regulates insulin action and degradation by interacting with insulin receptor substrate-1 and 14-3-3 epsilon. 27
Thiazolidinediones control the expression of phosphoprotein enriched in diabetes (ped/pea-15) both in vitro and in vivo 27
Antagonism between Hepatocyte Nuclear Factor 4 alpha (HNF4 alpha) and Chicken Ovalbumin Upstream Promoter-Transcription Factor 2 (COUP-TFII) modulates Ped/Pea-15 gene expression 27
PREP1 deficiency downregulates hepatic lipogenesis and attenuates steatohepatitis in mice. 27
Resveratrol Improves Endothelial Function by A PREP1-Mediated Pathway in Mouse Aortic Endothelial Cells 26
Receptor-mediated internalization of insulin: potential role of pp120/HA4, a substrate of the insulin receptor kinase 26
Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase. 25
PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis 25
Ped/pea-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells 25
Thiazolidinediones control the expression of Ped/Pea-15 (phosphoprotein enriched in diabetes) both in vitro and in vivo 25
Insulin stimulates phosphoinositides-dependent kinase (PDK)-1 binding to insulin-receptor C-terminus followed by tyrosine-phosphorylation and activation. 25
Protein kinase C-zeta and protein kinase B regulate distinct steps of insulin endocytosis and intracellular sorting 24
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction 24
TGF beta impairs muscle differentiation and induces autophagy by PED/PEA-15-mediated pathway 23
PED/PEA-15 controls TGFbeta production and fibronectin secretion through a PLD/PKCbeta pathway 23
Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism. 22
Overexpression of the ped/pea-15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin action 22
The function of PED, a novel gene in type 2 diabetes 22
The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes 22
Thrombin-activated platelets enhance healing of ulcerative skin lesion by inducing IGF-1 release by skin fibroblasts 21
The PED/PEA-15 diabetogene as a potential thiazolidinedione target 20
Transforming growth factor-beta increases the expression of PED/PEA-15 and glucose uptake via smad-3 phosphorylation in l6 cells 20
Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development 20
Mouse models of insulin resistance 19
Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of PED/PEA-15 gene 19
null 18
In skeletal muscle cells advanced glycation end products inhibit insulin action by inducing the formation of a multi-molecular complex which includes RAGE, PKCalpha and IRS1 17
EVOO Polyphenols Exert Anti-Inflammatory Effects on the Microglia Cell through TREM2 Signaling Pathway 16
Prep1 Controls Insulin Glucoregulatory Function in Liver by Transcriptional Targetting of SHP1 Tyrosine Phosphatase 15
null 12
Protein kinase C (PKC)-alpha activation inhibits PKC-zeta and mediates the action of PED/PEA-15 on glucose transport in the L6 skeletal muscle cells 10
The IR1152 mutant insulin receptor selectively impairs insulin action in skeletal muscle but not in liver 9
Totale 3.402
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Categoria #
all - tutte 17.229
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.229
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202096 0 0 0 0 0 0 0 1 7 15 33 40
2020/2021265 19 11 59 15 18 32 60 3 22 2 22 2
2021/2022564 5 0 9 4 12 18 12 16 89 36 145 218
2022/2023591 96 61 25 25 74 74 3 40 87 68 26 12
2023/2024427 12 56 34 26 36 75 6 58 8 10 75 31
2024/2025904 141 121 21 37 91 112 265 116 0 0 0 0
Totale 3.402