IRIS
TAGLIALATELA, MAURIZIO
 Distribuzione geografica
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Continente #
NA - Nord America 2.890
EU - Europa 1.918
AS - Asia 1.714
SA - Sud America 124
AF - Africa 25
Continente sconosciuto - Info sul continente non disponibili 2
Totale 6.673
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Nazione #
US - Stati Uniti d'America 2.748
SG - Singapore 803
IT - Italia 791
CN - Cina 389
HK - Hong Kong 382
RU - Federazione Russa 220
FI - Finlandia 198
NL - Olanda 169
DE - Germania 138
CA - Canada 136
BR - Brasile 115
UA - Ucraina 108
IE - Irlanda 100
VN - Vietnam 93
SE - Svezia 51
GB - Regno Unito 48
AT - Austria 23
CI - Costa d'Avorio 17
PL - Polonia 15
IN - India 13
BE - Belgio 12
FR - Francia 11
GR - Grecia 7
MX - Messico 6
AR - Argentina 5
BG - Bulgaria 5
ES - Italia 5
IS - Islanda 5
JP - Giappone 5
TR - Turchia 5
IR - Iran 4
BD - Bangladesh 3
IL - Israele 3
OM - Oman 3
AL - Albania 2
CH - Svizzera 2
DK - Danimarca 2
EC - Ecuador 2
EU - Europa 2
IQ - Iraq 2
MA - Marocco 2
PK - Pakistan 2
RO - Romania 2
AO - Angola 1
BN - Brunei Darussalam 1
CL - Cile 1
EG - Egitto 1
GE - Georgia 1
KR - Corea 1
LB - Libano 1
LK - Sri Lanka 1
LT - Lituania 1
ML - Mali 1
MY - Malesia 1
NG - Nigeria 1
NO - Norvegia 1
PY - Paraguay 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
TG - Togo 1
TN - Tunisia 1
UZ - Uzbekistan 1
Totale 6.673
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Città #
Singapore 553
Chandler 384
Hong Kong 382
Millbury 265
Princeton 187
Naples 167
Santa Clara 158
Jacksonville 154
Ashburn 131
Amsterdam 129
Ottawa 119
Nanjing 103
Dong Ket 93
Des Moines 83
Napoli 75
Beijing 71
Boston 62
Wilmington 58
Seattle 47
Milan 43
Nanchang 36
Marano di Napoli 35
Formia 33
Norwalk 33
Shenyang 30
Lawrence 26
Hebei 23
Tianjin 22
Houston 19
Washington 17
Breda 16
Jiaxing 16
Nuremberg 16
Trentola-Ducenta 16
Gdansk 15
Dublin 14
Falkenstein 14
Helsinki 14
Moscow 14
Falls Church 13
Verona 13
Guangzhou 12
Changsha 11
São Paulo 11
The Dalles 11
Kunming 10
Vienna 10
Ann Arbor 9
Boardman 9
Jordanstown 9
Rome 9
Vancouver 9
Cagliari 8
Redmond 8
Kronberg 7
Pozzuoli 7
Redwood City 7
Waanrode 7
Dearborn 6
Hangzhou 6
Orange 6
Toronto 6
Bhopal 5
Indiana 5
New York 5
Reykjavík 5
Salerno 5
San Mateo 5
Sofia 5
Acri 4
Augusta 4
Barano d'Ischia 4
Belo Horizonte 4
Bovisio-Masciago 4
Cisterna di Latina 4
Fairfield 4
Fisciano 4
Florence 4
Frankfurt am Main 4
Istanbul 4
Los Angeles 4
Menlo Park 4
Ningbo 4
Pescara 4
Rio de Janeiro 4
Shenzhen 4
Stockholm 4
Turin 4
Woodbridge 4
Belfast 3
Bisaccia 3
Brugherio 3
Chengdu 3
Fortaleza 3
Genoa 3
Giugliano In Campania 3
Hanover 3
Jinan 3
Linköping 3
London 3
Totale 4.025
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Nome #
A novel hyperekplexia-causing mutation in the pre-trasmembrane segm 1 of the human glycine receptor alpha 1 subunit reduces membrane expression and impairs gating by agonists 104
Caratterizzazione biochimica e funzionale in oociti di Xenopus Laevis e cellule CHO (Chinese Hamster Ovary Cells) di mutazioni nel gene Kcnq2 riscontrate in famiglie affette da convulsioni benigne neonatali 97
Decreased subunit stability as a novel mechanism for potassium current impairment by a KCNQ2 C terminus mutation causing benign familial neonatal convulsions 77
Tryptamine-based derivatives as Transient Receptor Potential Melastatin type-8 (TRPM8) channel modulators 66
Involvement of KCNQ2 subunits in [3H]dopamine release triggered by depolarization and pre-synaptic muscarinic receptor activation from rat striatal synaptosomes. 64
Pharmacological Targeting Of Neuronal Kv7.2/3 Channels: A Focus On Chemotypes And Receptor Sites 63
Decreased Subunit Stability as a Novel Mechanismfor PotassiumCurrent Impairment by a KCNQ2 C Terminus Mutation Causing Benign Familial Neonatal Convulsions 62
Non-invasive real-time in-vivo monitoring of insulin absorption from subcutaneous tissues 60
Addressing the use of PDIF-CN2 molecules in the development of n-type organic field-effect transistors for biosensing applications 57
Autism and developmental disability caused by KCNQ3 gain-of-function variants 56
A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy 55
A novel mutation in KCNQ2 associated to BFNC, drug resistant epilepsy and mental retardation 54
A micro-bioimpedance meter for monitoring insulin bioavailability in personalized diabetes therapy 54
Up-regulation and increased activity of KV3.4 channels and their accessory subunit MinK-related peptide 2 induced by amyloid peptide are involved in apoptotic neuronal death 53
Early treatment with quinidine in two patients with epilepsy of infancy with migrating focal seizures (EIMFS) due to gain-of-function KCNT1 mutations: functional studies, clinical responses and critical issues for personalized therapy 53
A novel KCNQ2 K+ channel mutation in benign neonatal convulsions and centrotemporal spikes 52
A novel KCNQ3 mutation in familial epilepsy with focal seizures and intellectual disability 52
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators 52
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 51
A y(+)LAT-1 mutant protein interferes with y(+)LAT-2 activity: implications for the molecular pathogenesis of lysinuric protein intolerance. 51
Regulation of the human ether-a-gogo related gene (HERG) K+ channels by reactive oxygen species 51
The voltage-sensing domain of Kv7.2 channels as a molecular target for epilepsy-causing mutations and anticonvulsants 51
Neuronal potassium channel openers in the management of epilepsy: Role and potential of retigabine 51
GAIN-OF-FUNCTION DUE TO INCREASED OPENING PROBABILITY BY TWO KCNQ5 PORE VARIANTS CAUSING DEVELOPMENTAL AND/OR EPILEPTIC ENCEPHALOPATHY 51
Brain distribution of the Na+/Ca2+ exchanger-encoding genes NCX1, NCX2, and NCX3 and their related proteins in the central nervous system 50
Gender-related issues in the pharmacology of new anti-obesity drugs 50
Insights into the pathogenesis of ATP1A1-related CMT disease using patient-specific iPSCs 50
Differential expression of the Na+-Ca2+ exchanger transcripts and proteins in rat brain regions 49
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits 49
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs). 48
M Channels Containing KCNQ2 Subunits Modulate Norepinephrine, Aspartate, and GABA Release from Hippocampal Nerve Terminals 48
Driving with no brakes: Molecular pathophysiology of Kv7 potassium channels 48
Activation of Kv7 potassium channels inhibits intracellular Ca2+ increases triggered by TRPV1-mediated pain-inducing stimuli in F11 immortalized sensory neurons 48
Functional analysis of novel KCNQ2 and KCNQ3 gene variants found in a large pedigree with benign familial neonatal convulsions (BFNC) 47
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate 47
Expression pattern of the ether-a-gogo-related (ERG) k+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system 46
Genotype-phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7.2 potassium channel subunits 46
Neurobiology of coronaviruses: Potential relevance for COVID-19 46
Generation of an iPSC line (UNINAi001-A) from a girl with neonatal-onset epilepsy and non-syndromic intellectual disability carrying the homozygous KCNQ3 p.PHE534ILEfs*15 variant and of an iPSC line (UNINAi002-A) from a non-carrier, unaffected brother 46
Genotype-phenotype correlations in patients with de novo KCNQ2 pathogenic variants 46
Differential expression of the Na+-Ca2+ exchanger transcripts and proteins in rat brain regions. 45
Lysinuric protein intolerance: identification and functional analysis of mutations of the SLC7A7 gene. 45
Retigabine and flupirtine exert neuroprotective actions in organotypic hippocampal cultures 45
Benign familial neonatal convulsions caused by altered gating of KCNQ2/KCNQ3 potassium channels 45
“One Health” Approach for Health Innovation and Active Aging in Campania (Italy) 45
Human ether-a-gogo related gene (HERG) K+ channels as pharmacological targets: present and future implications 44
A pharmacological study on the possible mechanisms underlying changes in TSH secretion in aged male rats 44
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction 44
Cardiac ion channels and antihistamines: possible mechanisms of cardiotoxicity. 42
Histidines 578 and 587 in the S5-S6 linker of the human Ether-a-gogo Related Gene-1 K+ channels confer sensitivity to reactive oxygen species 42
Activation of pre-synaptic M-type K+ channels inhibits [3H]D-aspartate release by reducing Ca2+ entry through P/Q-type voltage-gated Ca2+ channels 42
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy. 42
Molecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channels 41
NEUROLOGICAL RISKS AND BENEFITS OF CYTOKINE-BASED TREATMENTS IN COVID-19: FROM PRECLINICAL TO CLINICAL EVIDENCE 41
Expression pattern of the ether-a-gogo-related (ERG) K+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system. 40
Atypical gating of M-type potassium channels conferred by mutations in uncharged residues in the S4 region of KCNQ2 causing benign familial neonatal convulsions 40
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 40
Kv7.3 Compound Heterozygous Variants in Early Onset Encephalopathy Reveal Additive Contribution of C-Terminal Residues to PIP2-Dependent K+ Channel Gating 40
Kv7.4 channels regulate potassium permeability in neuronal mitochondria 40
Molecular basis for the lack of HERG K+ channel block-related cardiotoxicity by the H1 receptor blocker cetirizine compared with other second-generation antihistamines 39
Histamine induces exocytosis and IL-6 production from human lung macrophages through interaction with H1 receptors 38
Human neoplastic mesothelial cells express voltage-gated sodium channels involved in cell motility 38
Epileptic encephalopathy in a patientwith a novel variant in the Kv7.2 S2 transmembrane segment: Clinical, genetic, and functional features 38
IgG Autoantibodies Against IgE from Atopic Dermatitis Can Induce the Release of Cytokines and Proinflammatory Mediators from Basophils and Mast Cells 38
Plasma prolactin levels in the inferior petrosal sinuses in various pituitary disorders during perihypophyseal phlebography 37
Pure uptake blockers of dopamine can reduce prolactin secretion: studies with diclofensine 37
Coupling between the voltage-sensing and phosphatase domains of Ci-VSP 37
Distinct epilepsy phenotypes and response to drugs in KCNA1 gain- and loss-of function variants 37
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism 36
Adenosine Receptors Modulate the Na+-Ca2+ Exchanger in Cerebral Nerve Endingsa 36
K(V)7 channels regulate muscle tone and nonadrenergic noncholinergic relaxation of the rat gastric fund 36
Kv7 channel activation reduces brain endothelial cell permeability and prevents kainic acid-induced blood-brain barrier damage 35
Differential Vulnerability of Cortical and Cerebellar Neurons in Primary Culture to Oxygen Glucose Deprivation followed by Reoxygenation. 35
Effects of manidipine and nitrendipine enantiomers on the plateau phase of K+-induced intracellular Ca2+ increase in GH3 cells. 35
Modulation of ion channels by reactive oxygen and nitrogen species: a pathophysiological role in brain aging? 35
Expression and function of Kv7.4 channels in rat cardiac mitochondria: Possible targets for cardioprotection 35
A Novel Kv7.3 Variant in the Voltage-Sensing S4 Segment in a Family With Benign Neonatal Epilepsy: Functional Characterization and in vitro Rescue by β-Hydroxybutyrate 35
Blockade of herg K+ channels by second-generation H1 receptor-antagonists may regulate [Ca2+]i oscillations in GH3 cells 34
Expression, Localization, and Pharmacological Role of Kv7 Potassium Channels in Skeletal Muscle Proliferation, Differentiation, and Survival after Myotoxic Insults 34
Pharmacological blockade of ERG K+ channels and Ca2+ influx through store-operated channels exerts opposite effects on intracellular Ca2+ oscillations in pituitary GH3 cells 33
Manidipine and Nitrendipine R and S enantiomers block voltage-gated Ca2+ channel (VGCC) with different kinetic in GH3 cell 33
Specification of skeletal muscle differentiation by repressor element-1 silencing transcription factor (REST)-regulated Kv7.4 potassium channels 33
Identification of a Potent Tryptophan-based TRPM8 Antagonist With in vivo Analgesic Activity 33
Modulation of ion channels by reactive oxygen and nitrogen species: a pathophysiological role in brain aging? 32
A new Italian FHM2 family: Clinical aspects and functional analysis of the disease-associated mutation 32
Prolonged exposure of pituitary dopaminergic receptors to the phospholipid phosphatidylserine increases their sensitivity to dopamine in aged rats 31
Towards the realization of label-free biosensors through impedance spectroscopy integrated with IDES technology. 31
Gating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain 31
Cardiotoxic effects of antihistamines: From basics to clinics (...and back) 31
Cardiac safety of second-generation H1 -antihistamines when updosed in chronic spontaneous urticaria 31
KCNT2-related disorders: phenotypes, functional and pharmacological properties 30
Case report: Marked electroclinical improvement by fluoxetine treatment in a patient with KCNT1-related drug-resistant focal epilepsy 30
Identification of Drugs Acting as Perpetrators in Common Drug Interactions in a Cohort of Geriatric Patients from Southern Italy and Analysis of the Gene Polymorphisms That Affect Their Interacting Potential 30
Nuclear Factor-kappaB activation by reactive oxygen species mediates voltage-gated K+ current enhancement by neurotoxic beta-amyloid peptides in nerve growth factor-differentiated PC-12 cells and hippocampal neurones 30
Effects of pharmacological manipulation of calcium channels on endogenous dopamine release from tuberoinfundibular neurons 30
Correlating the Clinical and Genetic Features of Benign Familial Neonatal Seizures (BFNS) with the Functional Consequences of Underlying Mutations 30
Molecular and pharmacological evidence for a facilitatory functional role of pre-synaptic GLUK2/3 kainate receptors on GABA release in rat trigeminal caudal nucleus 30
KCNQ3 is the principal target of retigabine in CA1 and subicular excitatory neurons 30
Protein-tyrosine kinases activate while protein-tyrosine phosphatases inhibit L-type calcium channel activity in pituitary GH3 cells. 29
Molecular mechanisms involved in beta-amyloid-induced enhancement of voltage-gated K+ channels during neuronal apoptosis 29
Totale 4.382
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Categoria #
all - tutte 35.147
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 35.147
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020244 0 0 0 0 0 0 0 2 2 44 101 95
2020/2021498 19 32 31 31 42 78 38 33 39 16 44 95
2021/20221.029 14 7 5 14 15 33 10 38 120 62 213 498
2022/20231.166 229 118 21 148 135 98 8 73 150 132 44 10
2023/2024826 40 93 97 52 60 79 22 71 19 17 189 87
2024/20252.116 306 359 27 50 104 215 726 329 0 0 0 0
Totale 7.010