IRIS
SECONDO, AGNESE
 Distribuzione geografica
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Continente #
NA - Nord America 3.346
EU - Europa 2.285
AS - Asia 1.137
AF - Africa 73
SA - Sud America 8
Continente sconosciuto - Info sul continente non disponibili 2
Totale 6.851
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Nazione #
US - Stati Uniti d'America 3.269
IT - Italia 1.139
SG - Singapore 547
CN - Cina 453
DE - Germania 245
UA - Ucraina 233
NL - Olanda 179
FI - Finlandia 167
IE - Irlanda 119
CI - Costa d'Avorio 73
CA - Canada 71
GB - Regno Unito 70
VN - Vietnam 40
SE - Svezia 38
FR - Francia 29
IN - India 24
HK - Hong Kong 23
RU - Federazione Russa 15
ES - Italia 12
CH - Svizzera 11
JP - Giappone 11
TR - Turchia 11
BE - Belgio 10
IR - Iran 7
MX - Messico 6
BR - Brasile 4
IL - Israele 4
KR - Corea 4
PL - Polonia 4
AT - Austria 3
CL - Cile 3
ID - Indonesia 3
AM - Armenia 2
BG - Bulgaria 2
CZ - Repubblica Ceca 2
EU - Europa 2
NO - Norvegia 2
PH - Filippine 2
PK - Pakistan 2
SA - Arabia Saudita 2
DK - Danimarca 1
HU - Ungheria 1
KG - Kirghizistan 1
LT - Lituania 1
PE - Perù 1
PT - Portogallo 1
RO - Romania 1
TW - Taiwan 1
Totale 6.851
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Città #
Chandler 599
Singapore 451
Ashburn 395
Jacksonville 234
Santa Clara 196
Napoli 188
Amsterdam 162
Millbury 153
Princeton 124
Nanjing 108
Beijing 107
Naples 107
Boston 92
Ottawa 64
Wilmington 63
Rome 46
Helsinki 42
Formia 41
Dong Ket 40
Des Moines 39
Lawrence 38
Dearborn 37
Milan 34
Nanchang 27
Norwalk 20
Salerno 20
Hebei 17
Shenyang 17
Changsha 16
Falkenstein 16
Kronberg 15
Portici 15
Tianjin 15
Jiaxing 14
Seattle 14
Caserta 13
Dublin 13
Houston 13
Pavullo Nel Frignano 13
Woodbridge 13
Falls Church 11
Parma 11
Washington 11
Abano Terme 10
Boardman 9
Pune 9
Sudbury 9
Hefei 8
Redwood City 8
Turin 8
Augusta 7
Castel Campagnano 7
Dallas 7
Guangzhou 7
Highland Park 7
Hong Kong 7
Valladolid 7
Bologna 6
Cambridge 6
Fairfield 6
Frankfurt am Main 6
Kunming 6
Lappeenranta 6
Los Angeles 6
Menlo Park 6
Toronto 6
Bari 5
Florence 5
Mountain View 5
Palermo 5
Sant'arpino 5
Ann Arbor 4
Barano d'Ischia 4
Baronissi 4
Brembate di Sopra 4
Brugg 4
Brussels 4
Catania 4
Changchun 4
Chengdu 4
Courcelles 4
Hangzhou 4
Indiana 4
Ningbo 4
Orange 4
Pompei 4
Clifton 3
Edinburgh 3
Fremont 3
Genoa 3
Hyderabad 3
Itacoatiara 3
Jinan 3
London 3
Monteforte Irpino 3
Monza 3
Mugnano di Napoli 3
Munich 3
New Delhi 3
New York 3
Totale 3.955
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Nome #
Studio del ruolo della proteina AKAP121 nel controllo della funzionalità mitocondriale in modelli cellulari di anossia/reossigenazione come bersaglio per lo sviluppo di molecole di potenziale impiego terapeutico nell'ischemia cerebrale 331
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 320
Profarmaci dell’arginina con elevata attività terapeutica 147
The pharmacological activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons exposed to the cycad neurotoxin L-BMAA by promoting autophagic clearance 99
Na+/Ca2+ exchanger 1 on nuclear envelope controls PTEN/Akt pathway via nucleoplasmic Ca2+ regulation during neuronal differentiation 77
ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia. 72
A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage. 65
Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt 63
ApoSOD1 lacking dismutase activity neuroprotects motor neurons exposed to beta-methylamino-L-alanine through the Ca(2+)/Akt/ERK1/2 prosurvival pathway 63
Involvement of the nitric oxide/protein kinase G pathway in polychlorinated biphenyl-induced cell death in SH-SY 5Y neuroblastoma cells 62
Zinc inhibits calcium-mediated and nitric oxide-mediated ion secretion in human enterocytes 62
Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation 62
The functional coupling between endoplasmic reticulum and lysosomes for intracellular Ca2+ handling is disrupted in brain ischemia 62
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 61
Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis 61
Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors. STAIANO and LOFFREDO are CO-FIRST AUTHORS. 60
Oleic acid promotes prostate cancer malignant phenotype via the G protein-coupled receptor FFA1/GPR40 60
NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum. 59
CuZn Superoxide dismutase increases intracellular calcium levels via phospholipase C-protein Kinase C pathway in SK-N-BE cells 59
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential 59
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 56
Differentiation of monocytes into macrophages induces the upregulation of histamine H1 receptor. 54
Cigarette Smoke Condensate Causes a Decrease of the Gene Expression of Cu-Zn Superoxide Dismutase, Mn Superoxide Dismutase, Glutathione Peroxidase, Catalase, and Free Radical-Induced Cell Injury in SH-SY5Y Human Neuroblastoma Cells 54
D-Aspartate treatment attenuates myelin damage and stimulates myelin repair 53
The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance 53
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 52
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 51
Genetically modified mice as a strategy to unravel the role played by the na(+)/ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits 51
Galactosyl derivatives of L-arginine and D-arginine: synthesis, stability, cell permeation, and nitric oxide production in pituitary GH3 cells 50
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+exchanger 3 downregulation 50
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 50
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential. 49
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 49
The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia 48
A New Cell-penetrating Peptide That Blocks the Autoinhibitory XIP Domain of NCX1 and Enhances Antiporter Activity 48
Human trisomic ipscs from down syndrome fibroblasts manifest mitochondrial alterations early during neuronal differentiation 48
TSH/cAMP up-regulate sarco/endoplasmic reticulum Ca2+-ATPases expression and activity in PC Cl3 thyroid cells 47
Anoxia-induced NF-kappaB-dependent upregulation of NCX1 contributes to Ca2+ refilling into endoplasmic reticulum in cortical neurons 47
Synthesis of cyclic N1-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells 47
The Anemonia sulcata Toxin BDS-I Protects Astrocytes Exposed to Aβ1–42 Oligomers by Restoring [Ca2+]i Transients and ER Ca2+ Signaling 47
The antiepileptic drug Leviracetam decreases the IP3-dependent [Ca2+] increase induced by ATP and BK in PC12 cells 46
Identification and characterization of the promoter and transcription factors regulating the expression of cerebral sodium/calcium exchanger 2 (NCX2) gene 46
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 45
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells 45
Gliadin Peptides Induce Tissue Transglutaminase Activation and ER-Stress through Ca(2+) Mobilization in Caco-2 Cells. 45
NCX1 is a new rest target gene: role in cerebral ischemia 45
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death 45
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 44
A1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 44
Aβ1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation 44
. Ab1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 44
Pharmacology of Amyotrophic Lateral Sclerosis Old Strategies and New Perspectives 44
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage. 43
Anti-tissue transglutaminase antibodies activate intracellular tissue transglutaminase by modulating cytosolic Ca2+ homeostasis. 43
Synthesis and Biological Evaluation of a New Structural Simplified Analogue of cADPR, a Calcium-Mobilizing Secondary Messenger Firstly Isolated from Sea Urchin Eggs 43
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs). 42
Effects of HIV-1 Tat protein on ion secretion and on cell proliferation in human intestinal epithelial cells 42
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. 41
Cu,Zn superoxide dismutase increases intracellular calcium levels via a phospholipase C-protein kinase C pathway in SK-N-BE neuroblastoma cells 41
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 41
Pioglitazone improves mitochondrial organization and bioenergetics in down syndrome cells 41
The Na+/Ca2+ exchangers in demyelinating diseases 41
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs). 40
Glutamate-independent calcium toxicity: Introduction. 40
Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase 40
Principi di farmacologia clinica, materna e fetale 40
SOD1 PREVENTS MOTOR NEURON DEATH INDUCED BY THE CYCAD NEUROTOXIN BETA-METHYLAMINO-L-ALANINE BY MODULATING PLASMA MEMBRANE TARGETS INVOLVED IN INTRACELLULAR Ca2+ HOMEOSTASIS 40
Generation of an iPSC line (UNINAi001-A) from a girl with neonatal-onset epilepsy and non-syndromic intellectual disability carrying the homozygous KCNQ3 p.PHE534ILEfs*15 variant and of an iPSC line (UNINAi002-A) from a non-carrier, unaffected brother 40
Prolonged NCX activation prevents SOD1 accumulation, reduces neuroinflammation, ameliorates motor behavior and prolongs survival in a ALS mouse model 40
Expression and function of Na+/Ca2+ exchangers 1 and 3 in human macrophages and monocytes 39
Effects of D-aspartate on oligodendrocytes during differentiation, demyelination and remyelination processes 39
ORAI1/STIM1 INTERACTION INTERVENES IN STROKE AND IN NEUROPROTECTION INDUCED BY ISCHEMIC PRECONDITIONING THROUGH ER Ca2+ REFILLING 39
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 38
Activation of pre-synaptic M-type K+ channels inhibits [3H]D-aspartate release by reducing Ca2+ entry through P/Q-type voltage-gated Ca2+ channels 38
Human macrophages and monocytes express functional na(+)/ca (2+) exchangers 1 and 3 37
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 37
Calcium Dyshomeostasis and Lysosomal Ca2+ Dysfunction in Amyotrophic Lateral Sclerosis 37
A1-42 fragment induces an up-regulation of NCX3 activity that prevents caspase-12 activation. 36
Histamine induces exocytosis and IL-6 production from human lung macrophages through interaction with H1 receptors 35
Glutamate-independent calcium toxicity: introduction 35
Neurounina-1, a Novel Compound that Increases Na+/Ca2+ Exchanger Activity, Effectively Protects Against Stroke Damage 35
The antiepileptic drug levetiracetam decreases the inositol 1,4,5-trisphosphate-dependent [Ca2+]I increase induced by ATP and bradykinin in PC12 cells 35
Genetically modified mice to unravel physiological and pathophysiological roles played by NCX isoforms 35
Probing the Ca2+ mobilizing properties on primary cortical neurons of a new stable cADPR mimic 35
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells. 34
Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia. 34
The antioxidant activity of limonene counteracts neurotoxicity triggered byaβ1-42 oligomers in primary cortical neurons 34
SARS-CoV-2 Spike Protein Activates Human Lung Macrophages 33
Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia. 33
NCX1 Expression and Functional Activity Increase in Microglia Invading the Infarct Core 33
Nitric oxide stimulates NCX1 and NCX2 but inhibits NCX3 isoform by three distinct molecular determinants 33
ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na(+) /Ca(2+) exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells. 33
The modulation of intracellular Ca2+ homeostasis is involved in SOD1 and ApoSOD1-induced neuroprotection of motor neurons exposed to beta-methylamino-L-alanine 33
Na+/Ca2+ exchanger isoform 1 takes part to the Ca2+-related prosurvival pathway of SOD1 in primary motor neurons exposed to beta-methylamino-l-alanine 33
'Janus face' of nitric oxide action on plasma membrane and intracellular ionic channels. 32
Nitric oxide induces [Ca2+]i oscillations in pituitary GH3 cells: involvement of IDR and ERG K+ currents 32
The Na+/Ca2+ Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia 32
A new concept: Aβ1-42 generates a hyperfunctional proteolytic NCX3 fragment that delays caspase-12 activation and neuronal death 32
New Insights into the Structure-Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na+/Ca2+Exchanger Isoforms 32
The antiepileptic drug levetiracetam decreases the inositol 1,4,5-trisphosphate-dependent [Ca2+]I increase induced by ATP and bradykinin in PC12 cells. 31
Totale 5.217
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Categoria #
all - tutte 31.015
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 31.015
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020331 0 0 0 0 0 12 47 16 16 48 86 106
2020/2021657 24 53 70 69 70 79 52 13 85 18 68 56
2021/20221.070 26 8 13 13 18 28 13 55 119 97 323 357
2022/20231.419 187 130 48 112 156 157 19 116 201 176 75 42
2023/20241.269 38 148 101 104 60 89 24 399 23 39 149 95
2024/20251.105 237 275 49 91 161 292 0 0 0 0 0 0
Totale 7.151