IRIS
MEDINA SANABRIA, Diego Luis
 Distribuzione geografica
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Continente #
NA - Nord America 1.063
EU - Europa 619
AS - Asia 355
AF - Africa 30
OC - Oceania 1
SA - Sud America 1
Totale 2.069
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Nazione #
US - Stati Uniti d'America 1.037
IT - Italia 387
SG - Singapore 196
CN - Cina 149
NL - Olanda 79
UA - Ucraina 36
CI - Costa d'Avorio 29
IE - Irlanda 29
FI - Finlandia 26
CA - Canada 25
DE - Germania 20
SE - Svezia 14
FR - Francia 12
GB - Regno Unito 7
ES - Italia 2
IN - India 2
JP - Giappone 2
KR - Corea 2
BE - Belgio 1
BG - Bulgaria 1
BR - Brasile 1
BZ - Belize 1
EE - Estonia 1
HR - Croazia 1
IQ - Iraq 1
MD - Moldavia 1
NG - Nigeria 1
NZ - Nuova Zelanda 1
PL - Polonia 1
RU - Federazione Russa 1
SA - Arabia Saudita 1
TW - Taiwan 1
VN - Vietnam 1
Totale 2.069
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Città #
Chandler 253
Singapore 153
Naples 92
Amsterdam 73
Ashburn 63
Millbury 54
Napoli 50
Boston 48
Nanjing 45
Santa Clara 45
Lawrence 43
Des Moines 41
Beijing 33
Princeton 25
Wilmington 23
Ottawa 22
Rome 13
Nanchang 12
Milan 10
Lappeenranta 8
Shenyang 8
Washington 8
Fairfield 7
Jacksonville 7
Jiaxing 7
Los Angeles 7
Dearborn 6
Hebei 6
Houston 6
Padova 6
Canegrate 5
Changsha 5
Casoria 4
Dallas 4
Florence 4
Kunming 4
Marsicovetere 4
Norwalk 4
San Jose 4
Shanghai 4
Siena 4
Tianjin 4
Bacoli 3
Bungay 3
Caserta 3
Clifton 3
Felitto 3
Salerno 3
Torino 3
Trecase 3
Turin 3
Acerra 2
Agropoli 2
Avellino 2
Aversa 2
Aviano 2
Boardman 2
Budrio 2
Capodrise 2
Chiusi 2
Ciampino 2
Dublin 2
Eboli 2
Forest Hills 2
Formia 2
Fuzhou 2
Gorle 2
Grafing bei Munchen 2
Gwanak-gu 2
Kronberg 2
Monopoli 2
New York 2
Palma Campania 2
Qualiano 2
Saint-Fons 2
Sezze 2
Venezia 2
Verona 2
Zeist 2
Andover 1
Arezzo 1
Arzano 1
Auckland 1
Baghdad 1
Belize City 1
Bergamo 1
Boscoreale 1
Brussels 1
Cambridge 1
Cardito 1
Casamicciola Terme 1
Chisinau 1
Chongqing 1
Como 1
Edinburgh 1
Falls Church 1
Forio 1
Fort Worth 1
Fremont 1
Grünwald 1
Totale 1.328
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Nome #
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 118
Light-responsive microRNA miR-211 targets Ezrin to modulate lysosomal biogenesis and retinal cell clearance 99
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 74
FGF signalling regulates bone growth through autophagy 64
Activation of the transcription factor EB rescues lysosomal abnormalities in cystinotic kidney cells 57
Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders 50
Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB 47
The activity of Sac1 across ER-TGN contact sites requires the four-phosphate-adaptor-protein-1 43
miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network. 42
A reverse-engineering approach to dissect post-translational modulators of transcription factor's activity from transcriptional data 42
A Block of Autophagy in Lysosomal Storage Disorders 40
Regional- and age-dependent reduction in trkB receptor expression in the hippocampus is associated with altered spine morphologies 37
Comparing structural and transcriptional drug networks reveals signatures of drug activity and toxicity in transcriptional responses 36
Correction of oxidative stress enhances enzyme replacement therapy in Pompe disease 36
Current methods to analyse lysosome morphology, positioning, motility and function 36
EGR1 drives cell proliferation by directly stimulating TFEB transcription in response to starvation 35
Automatic identification of small molecules that promote cell conversion and reprogramming 35
Methods to Monitor and Manipulate TFEB Activity During Autophagy 34
mTOR-dependent phosphorylation controls TFEB nuclear export 34
c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder 34
Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis 33
Fingolimod Phosphate Inhibits Astrocyte Inflammatory Activity in Mucolipidosis IV 31
Somatostatin is expressed in FRTL-5 thyroid cells and prevents thyrotropin-mediated down-regulation of the cyclin-dependent kinase inhibitor p27kip1 31
TRPML1-/TFEB-dependent regulation of lysosomal exocytosis 30
Mechanism of TrkB-mediated hippocampal long-term potentiation 30
Autophagy modulator scoring system: a user-friendly tool for quantitative analysis of methodological integrity of chemical autophagy modulator studies 30
The rapidly evolving view of lysosomal storage diseases 30
A Gene Network Regulating Lysosomal Biogenesis and Function 29
Signals from the lysosome: a control centre for cellular clearance and energy metabolism. 29
Ca2+-dependent regulation of TFEB and lysosomal function 29
Lysosomotropic Drugs: Pharmacological Tools to Study Lysosomal Function 29
TRPML1: The Ca(2+)retaker of the lysosome 29
Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL 28
TFEB Modulates p21/WAF1/CIP1 during the DNA Damage Response 28
Drug repurposing in rare diseases: An integrative study of drug screening and transcriptomic analysis in nephropathic cystinosis 28
TFEB Links Autophagy to Lysosomal Biogenesis. 26
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB. 26
TFEB and the CLEAR network. 26
gene2drug: a Computational Tool for Pathway-based Rational Drug Repositioning 26
NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program 26
A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition 25
Brain Disorders Due to Lysomal Dysfunction 25
Fluoxetine ameliorates mucopolysaccharidosis type IIIA 25
The Regulation of MiTF/TFE Transcription Factors Across Model Organisms: from Brain Physiology to Implication for Neurodegeneration 24
RhoA activation promotes transformation and loss of thyroid cell differentiation interfering with thyroid transcription factor-1 activity 23
TrkB regulates neocortex formation through the Shc/PLCgamma-mediated control of neuronal migration 23
Thyrotropin-dependent proliferation of in vitro rat thyroid cell systems 23
High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration 23
SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention 23
The phytoestrogen genistein modulates lysosomal metabolism and Transcription Factor EB (TFEB) activation. 22
null 22
TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry 21
Role of insulin and serum on thyrotropin regulation of thyroid transcription factor-1 and pax-8 genes expression in FRTL-5 thyroid cells 21
TFEB variants and uses thereof 21
Transcriptional activation of lysosomal exocytosis promotes cellular clearance. 20
TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy 20
Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis 20
Introduction of p53 induces cell-cycle arrest in p53-deficient human medullary-thyroid-carcinoma cells 19
The MDM2 oncoprotein promotes apoptosis in p53-deficient human medullary thyroid carcinoma cells 19
Cellular and Gene Expression Response to the Combination of Genistein and Kaempferol in the Treatment of Mucopolysaccharidosis Type I 19
High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction in Vitro and in Mouse Retina 18
Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation 18
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten disease 17
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells 17
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype 17
Synthetic lethality screening identifies fda-approved drugs that overcome atp7b-mediated tolerance of tumor cells to cisplatin 16
High-content drug screening for rare diseases 14
TRPML1 and TFEB, an Intimate Affair 13
Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes 13
TFEB phosphorylation inhibitors and uses thereof 13
Antagonistic effect of cyclin-dependent kinases and a calcium-dependent phosphatase on polyglutamine-expanded androgen receptor toxic gain of function 10
TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway 10
Pharmacological approaches to tackle NCLs 9
Lysosomal calcium and autophagy 9
Sestrin2 drives ER-phagy in response to protein misfolding 8
TFEB controls syncytiotrophoblast formation and hormone production in placenta 8
Investigation on lysosomal accumulation by a quantitative analysis of 2D phase-maps in digital holography microscopy 6
Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies 4
Lysosomal calcium regulates autophagy. 2
Totale 2.227
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Categoria #
all - tutte 10.382
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 10.382
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020141 0 0 0 0 11 3 16 4 28 28 34 17
2020/2021106 3 8 16 9 8 9 13 8 14 5 8 5
2021/2022327 12 9 9 5 6 9 8 12 40 19 35 163
2022/2023601 76 60 14 37 70 64 8 62 80 85 33 12
2023/2024449 26 64 61 39 18 32 17 47 20 29 64 32
2024/2025328 108 126 14 34 46 0 0 0 0 0 0 0
Totale 2.227