IRIS
DE SIMONE, Alfonso
 Distribuzione geografica
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Continente #
AS - Asia 4.039
NA - Nord America 2.810
EU - Europa 1.976
SA - Sud America 487
AF - Africa 85
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 1
Totale 9.401
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Nazione #
US - Stati Uniti d'America 2.711
SG - Singapore 2.007
RU - Federazione Russa 1.021
CN - Cina 650
VN - Vietnam 587
IT - Italia 384
BR - Brasile 379
HK - Hong Kong 379
FR - Francia 160
DE - Germania 133
BD - Bangladesh 84
FI - Finlandia 64
JP - Giappone 63
GB - Regno Unito 54
KR - Corea 53
IN - India 49
CA - Canada 39
AR - Argentina 35
MX - Messico 31
SE - Svezia 24
NL - Olanda 23
PH - Filippine 23
IQ - Iraq 22
AT - Austria 20
PL - Polonia 19
EC - Ecuador 18
PK - Pakistan 16
VE - Venezuela 14
TH - Thailandia 13
ZA - Sudafrica 13
MA - Marocco 12
PY - Paraguay 11
TW - Taiwan 11
ES - Italia 10
ID - Indonesia 10
AE - Emirati Arabi Uniti 9
NP - Nepal 9
TR - Turchia 9
CO - Colombia 8
DZ - Algeria 8
TN - Tunisia 8
CL - Cile 7
KE - Kenya 7
UZ - Uzbekistan 7
EG - Egitto 6
JO - Giordania 6
BE - Belgio 5
BO - Bolivia 5
BY - Bielorussia 5
JM - Giamaica 5
LT - Lituania 5
RO - Romania 5
SA - Arabia Saudita 5
SI - Slovenia 5
SN - Senegal 5
UA - Ucraina 5
CI - Costa d'Avorio 4
DO - Repubblica Dominicana 4
HN - Honduras 4
IE - Irlanda 4
NG - Nigeria 4
PE - Perù 4
AZ - Azerbaigian 3
BB - Barbados 3
BG - Bulgaria 3
CH - Svizzera 3
CZ - Repubblica Ceca 3
GR - Grecia 3
KZ - Kazakistan 3
MN - Mongolia 3
NI - Nicaragua 3
PS - Palestinian Territory 3
UY - Uruguay 3
AL - Albania 2
AM - Armenia 2
AU - Australia 2
BA - Bosnia-Erzegovina 2
CG - Congo 2
CR - Costa Rica 2
ET - Etiopia 2
GY - Guiana 2
HU - Ungheria 2
LB - Libano 2
ME - Montenegro 2
MR - Mauritania 2
SK - Slovacchia (Repubblica Slovacca) 2
BH - Bahrain 1
BJ - Benin 1
BS - Bahamas 1
BW - Botswana 1
CY - Cipro 1
DJ - Gibuti 1
DK - Danimarca 1
DM - Dominica 1
EE - Estonia 1
EU - Europa 1
GE - Georgia 1
GF - Guiana Francese 1
GH - Ghana 1
GM - Gambi 1
Totale 9.373
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Città #
Singapore 921
San Jose 605
Hong Kong 374
Moscow 284
Santa Clara 257
Ashburn 245
Hefei 234
Ho Chi Minh City 170
Naples 147
Millbury 139
The Dalles 137
Hanoi 124
Lauterbourg 118
Beijing 115
Lawrence 105
Chandler 103
Des Moines 78
Los Angeles 68
Redondo Beach 54
Helsinki 51
Tokyo 51
Buffalo 48
Seoul 42
Seattle 41
São Paulo 34
Wilmington 33
Dallas 29
Chicago 27
Da Nang 26
Frankfurt am Main 25
Haiphong 23
Nuremberg 23
Rome 23
Falkenstein 22
New York 22
Napoli 21
Belo Horizonte 18
Fairfield 17
Rio de Janeiro 15
Munich 13
Toronto 13
Bologna 12
Milan 12
Woodbridge 12
Boston 11
Denver 11
Florence 11
Lappeenranta 11
Mexico City 11
Orem 10
Warsaw 10
Baghdad 9
Brooklyn 9
Montreal 9
Porto Alegre 9
Atlanta 8
Cambridge 8
Chennai 8
Guangzhou 8
Lahore 8
Vienna 8
Wroclaw 8
Amsterdam 7
Asunción 7
Can Tho 7
Columbus 7
Düsseldorf 7
Mumbai 7
Nairobi 7
Nanjing 7
San Gennaro Vesuviano 7
Tashkent 7
Vĩnh Long 7
Baltimore 6
Biên Hòa 6
Cape Town 6
Council Bluffs 6
Evanston 6
Kronberg 6
Ninh Bình 6
Phoenix 6
Recife 6
Rockville 6
San Francisco 6
Shenzhen 6
Amman 5
Campinas 5
Caracas 5
Dakar 5
Dhaka 5
Dubai 5
Frisco 5
London 5
Manchester 5
Norwalk 5
Parma 5
Quận Ba 5
Salt Lake City 5
São Bernardo do Campo 5
Verona 5
Totale 5.322
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Nome #
Artificial heme-enzymes for the construction of functional nanomaterials 152
Classification of metal site coordination number and geometry through artificial neural networks 144
Structural basis of membrane disruption and cellular toxicity by a-synuclein oligomers 137
Membrane Interactions and Toxicity by Misfolded Protein Oligomers 131
The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains 129
Structural and Dynamic properties of incomplete immunoglobulin-like fold domains 124
α-Synuclein and Mitochondria: Probing the Dynamics of Disordered Membrane-protein Regions Using Solid-State Nuclear Magnetic Resonance 121
Prion and water: Tight and dynamical hydration sites have a key role in structural stability 120
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction 113
Intrinsic structural versatility of the highly conserved 412–423 epitope of the Hepatitis C Virus E2 protein 112
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease 111
The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes 110
Catalytic Nanomaterials by Conjugation of an Artificial Heme-Peroxidase to Amyloid Fibrils 107
The identification of adenylyl cyclase modulators as potential receptors for 6-nitrodopamine in human-induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and their relevance in heart inotropism 103
Backbone NMR assignments of HypF-N under conditions generating toxic and non-toxic oligomers 103
Structural Basis for Natural Product Selection and Export by Bacterial ABC Transporters 103
Structural differences between toxic and nontoxic HypF-N oligomers 102
Blocking von Willebrand factor free thiols inhibits binding to collagen under high and pathological shear stress 102
A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics 102
MetalHawk: Enhanced Classification of Metal Coordination Geometries by Artificial Neural Networks 101
Molecular determinants of the interaction of EGCG with ordered and disordered proteins 100
Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis 99
Characterization of the conformational equilibrium between the two major substates of RNase a using NMR chemical shifts 99
Modeling Parkinson’s disease neuropathology and symptoms by intranigral inoculation of preformed human α-synuclein oligomers 98
Sequence Specificity in the Entropy-Driven Binding of a Small Molecule and a Disordered Peptide 98
Conformational modifications of gB from Herpes simplex virus type 1 analyzed by synthetic peptides 97
Probing the Origin of the Toxicity of Oligomeric Aggregates of α-Synuclein with Antibodies 96
A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles 96
Order and disorder in the physiological membrane binding of α-synuclein 96
Accurate random coil chemical shifts from an analysis of loop regions in native states of proteins 94
In silico study of the mechanism of binding of the N-terminal region of α synuclein to synaptic-like membranes 92
The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41 91
α-Synuclein and biological membranes: the danger of loving too much 90
Glucokinase gene mutations: Structural and genotype-phenotype analyses in MODY children from South Italy 89
Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis 89
Cavitation energies can outperform dispersion interactions 89
Backbone NMR assignments of the C-terminal domain of the human prion protein and its disease-associated T183A variant 88
Water molecules as structural determinants among prions of low sequence identity 88
Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour 87
Demonstration of Binding Induced Structural Plasticity in a SH2 Domain 87
The Toxicity of Misfolded Protein Oligomers Is Independent of Their Secondary Structure 87
1H, 13C and 15N resonance assignments of human muscle acylphosphatase 86
Characterization of the Conformational Fluctuations in the Josephin Domain of Ataxin-3 85
Local structural motifs in proteins: Detection and characterization of fragments inserted in helices 85
Region-specific changes in gene expression are associated with cognitive deficits in the alpha-synuclein-induced model of Parkinson's disease: A transcriptomic profiling study 83
A Carboxylate to Amide Substitution That Switches Protein Folds 80
Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis 80
Desolvation of the substrate-binding protein TauA dictates ligand specificity for the alkanesulfonate ABC importer TauABC 80
Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses 79
Conformational recognition of an intrinsically disordered protein 77
Structural basis of synaptic vesicle assembly promoted by α-synuclein 77
Structural basis for allosteric control of the SERCA-Phospholamban membrane complex by Ca2+ and phosphorylation 76
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat 76
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease 76
Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity 76
Structure-Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates 75
Metal interactions of α-synuclein probed by NMR amide-proton exchange 73
A kink in DWORF helical structure controls the activation of the sarcoplasmic reticulum Ca2+-ATPase 72
Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity 72
Correlation between ω and ψ dihedral angles in protein structures 70
Immune responses to oligomeric α-synuclein in Parkinson's disease peripheral blood mononuclear cells 69
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition 69
Advances in modelling alpha-synuclein-induced Parkinson's diseases in rodents: Virus-based models versus inoculation of exogenous preformed toxic species 68
Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity 66
Protein kinase R dependent phosphorylation of α-synuclein regulates its membrane binding and aggregation 65
Amyloid fibrils as innovative catalysts for advanced functional materials 65
Editorial: Oligomers in amyloid-associated diseases-structural properties and toxicity 63
The Intranigral Infusion of Human-Alpha Synuclein Oligomers Induces a Cognitive Impairment in Rats Associated with Changes in Neuronal Firing and Neuroinflammation in the Anterior Cingulate Cortex 63
Characterizing protein crystal contacts and their role in crystallization: Rubredoxin as a case study 63
Repurposing Pomalidomide as a Neuroprotective Drug: Efficacy in an Alpha-Synuclein-Based Model of Parkinson’s Disease 62
Amyloid fibrils for the construction of functional materials 61
Plasticity of Membrane Binding by the Central Region of α-Synuclein 61
Thermal tuning of protein hydration in a hyperthermophilic enzyme 61
The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State 59
Toward an accurate determination of free energy landscapes in solution states of proteins 58
Josephin domain of ataxin-3 contains two distinct ubiquitin-binding sites 56
Atomic structure and hierarchical assembly of a cross-β amyloid fibril 56
Release of high-energy water as an essential driving force for the high-affinity binding of cucurbit[n]urils 54
Determination of conformational equilibria in proteins using residual dipolar couplings 54
Intrinsic disorder modulates protein self-assembly and aggregation 54
Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies 53
Stimuli-Responsive Hydrogels from Liquid–Liquid Phase Separations of FUS-Derived Peptides 52
Accurate Determination of Conformational Transitions in Oligomeric Membrane Proteins 52
Structural and hydration properties of the partially unfolded states of the prion protein 52
Characterizing intermolecular interactions that initiate native-like protein aggregation 52
Structure, dynamics, and stability of assemblies of the human prion fragment SNQNNF 52
Probing the dynamic stalk region of the ribosome using solution NMR 51
Under the Influence of Water: Molecular Recognition of Organic Hydrophilic Molecules in Water with a Prismarene Host Driven by Hydration Effects 50
Enhancing Biomolecular Simulations with Hybrid Potentials Incorporating NMR Data 50
Structure-Free Validation of Residual Dipolar Coupling and Paramagnetic Relaxation Enhancement Measurements of Disordered Proteins 50
Substitutions at residue 211 in the prion protein drive a switch between CJD and GSS syndrome, a new mechanism governing inherited neurodegenerative disorders 50
Deep-Learning Driven Identification of Novel Antimicrobial Peptides 49
Characterization of the interdomain motions in hen lysozyme using residual dipolar couplings as replica-averaged structural restraints in molecular dynamics simulations 49
Multi-scale simulations provide supporting evidence for the hypothesis of intramolecular protein translocation in GroEL/GroES complexes 49
Toward the understanding of MNEI sweetness from hydration map surfaces 49
The PROSECCO server for chemical shift predictions in ordered and disordered proteins 49
Force-field dependence of chignolin folding and misfolding: Comparison with experiment and redesign 49
New opportunities for tensor-free calculations of residual dipolar couplings for the study of protein dynamics 48
Dynamical properties of steric zipper polymorphs formed by a IAPP-derived peptide 48
Twisting transition between crystalline and fibrillar phases of aggregated peptides 48
Totale 7.984
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Categoria #
all - tutte 32.679
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 32.679
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202110 0 0 0 0 0 0 0 0 0 0 5 5
2021/2022328 11 9 1 1 9 10 4 25 12 1 16 229
2022/2023449 155 29 12 11 37 39 1 65 67 5 24 4
2023/2024387 21 34 39 18 19 14 6 45 7 8 120 56
2024/20252.812 162 123 28 33 126 229 300 195 237 267 857 255
2025/20265.387 511 482 488 482 975 181 632 433 688 296 219 0
Totale 9.580