Background: Urinary tract infections (UTIs) in kidney transplant patients are a challenge. Aim: To evaluate epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients in a university hospital for UTI. Methods: We conducted a retrospective observational study, enrolling all kidney transplant patients hospitalized for UTI, with the objective to evaluate the epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients. Results: From our real-life experience, infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection. At the same time, the re-evaluation of immunosuppressive therapy could be an important therapeutic strategy in the course of infection. Conclusion: Prompt initiation of empiric antibiotic therapy upon initiation of microbiological investigations may reduce the risk of severe infection progression.

Urinary tract infections in kidney transplant patients admitted to hospital: A real-life experience / Pinchera, B.; Carrano, R.; Schettino, E.; D'Agostino, A.; Trucillo, E.; Cuccurullo, F.; Salemi, F.; Piccione, A.; Gentile, I.. - In: WORLD JOURNAL OF TRANSPLANTATION. - ISSN 2220-3230. - 15:2(2025). [10.5500/wjt.v15.i2.99554]

Urinary tract infections in kidney transplant patients admitted to hospital: A real-life experience

Pinchera B.;Carrano R.;Trucillo E.;Piccione A.;
2025

Abstract

Background: Urinary tract infections (UTIs) in kidney transplant patients are a challenge. Aim: To evaluate epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients in a university hospital for UTI. Methods: We conducted a retrospective observational study, enrolling all kidney transplant patients hospitalized for UTI, with the objective to evaluate the epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients. Results: From our real-life experience, infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection. At the same time, the re-evaluation of immunosuppressive therapy could be an important therapeutic strategy in the course of infection. Conclusion: Prompt initiation of empiric antibiotic therapy upon initiation of microbiological investigations may reduce the risk of severe infection progression.
2025
Urinary tract infections in kidney transplant patients admitted to hospital: A real-life experience / Pinchera, B.; Carrano, R.; Schettino, E.; D'Agostino, A.; Trucillo, E.; Cuccurullo, F.; Salemi, F.; Piccione, A.; Gentile, I.. - In: WORLD JOURNAL OF TRANSPLANTATION. - ISSN 2220-3230. - 15:2(2025). [10.5500/wjt.v15.i2.99554]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11588/1019635
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