Mass spectrometry plays a central role in structural proteomics, particularly in highly intensive structural genomics projects. This review paper reports some examples taken from recent work from the authors' laboratory and is aimed at showing that modem proteomics strategies are instrumental in the integration of structural genomic projects in fields such as: (i) protein-protein interactions, (ii) protein-DNA interactions, (iii) protein-ligand interactions, and (iv) protein-folding intermediates.
Exploitation of proteomics strategies in protein structure-function studies / Marino, G.; Pucci, Pietro; Birolo, Leila; Ruoppolo, Margherita. - In: PURE AND APPLIED CHEMISTRY. - ISSN 0033-4545. - STAMPA. - 75:2-3(2003), pp. 309-316. [10.1351/pac200375020309]
Exploitation of proteomics strategies in protein structure-function studies
PUCCI, PIETRO;BIROLO, LEILA;RUOPPOLO, MARGHERITA
2003
Abstract
Mass spectrometry plays a central role in structural proteomics, particularly in highly intensive structural genomics projects. This review paper reports some examples taken from recent work from the authors' laboratory and is aimed at showing that modem proteomics strategies are instrumental in the integration of structural genomic projects in fields such as: (i) protein-protein interactions, (ii) protein-DNA interactions, (iii) protein-ligand interactions, and (iv) protein-folding intermediates.| File | Dimensione | Formato | |
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