The authors have developed a technique and a prototype for β-ray quantitative imaging of biological samples which have been radioactively labeled. The prototype is based on a solid state pixel detector, bump-bonded to a low threshold, single particle counting chip: the detector the authors used is 200-μm thick GaAs, with pixel size 170 μm. Here, they describe an experiment that shows the capability of monitoring a dynamic process. Specifically, [14C]L-Leucine uptake by eggs of mollusk cephalopod Octopus culgaris and the consequent migration of marker into the ooplasm was followed
Quantitative dynamic imaging of biological processes with solid state radiation detectors / L., Abate; Bertolucci, Ennio; Conti, Maurizio; DI COSMO, Anna; C., DI CRISTO; Mettivier, Giovanni; Montesi, MARIA CRISTINA; Russo, Paolo. - In: IEEE TRANSACTIONS ON NUCLEAR SCIENCE. - ISSN 0018-9499. - 47:6(2000), pp. 1907-1910. [10.1109/23.914468]
Quantitative dynamic imaging of biological processes with solid state radiation detectors.
BERTOLUCCI, ENNIO;CONTI, MAURIZIO;DI COSMO, ANNA;METTIVIER, GIOVANNI;MONTESI, MARIA CRISTINA;RUSSO, PAOLO
2000
Abstract
The authors have developed a technique and a prototype for β-ray quantitative imaging of biological samples which have been radioactively labeled. The prototype is based on a solid state pixel detector, bump-bonded to a low threshold, single particle counting chip: the detector the authors used is 200-μm thick GaAs, with pixel size 170 μm. Here, they describe an experiment that shows the capability of monitoring a dynamic process. Specifically, [14C]L-Leucine uptake by eggs of mollusk cephalopod Octopus culgaris and the consequent migration of marker into the ooplasm was followedI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
