The phosphotriester solid phase method based on the elongation of the chain in the 5'- to 3'-end direction was used for the synthesis of polydeoxyribonucleotides of 16-18 units contg. all 4 bases. New deprotection procedures and the use of above ambient temp. for coupling reactions are described.
Solid-phase synthesis of polynucleotides with defined sequences by the phosphotriester method based on the elongation of the chain in the 5' to 3'-end direction / DE NAPOLI, Lorenzo; Mayol, Luciano; Piccialli, Gennaro; C., Santacroce. - In: GAZZETTA CHIMICA ITALIANA. - ISSN 0016-5603. - STAMPA. - 114:(1984), pp. 471-473.
Solid-phase synthesis of polynucleotides with defined sequences by the phosphotriester method based on the elongation of the chain in the 5' to 3'-end direction.
DE NAPOLI, LORENZO;MAYOL, LUCIANO;PICCIALLI, GENNARO;
1984
Abstract
The phosphotriester solid phase method based on the elongation of the chain in the 5'- to 3'-end direction was used for the synthesis of polydeoxyribonucleotides of 16-18 units contg. all 4 bases. New deprotection procedures and the use of above ambient temp. for coupling reactions are described.File in questo prodotto:
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