Four Caribbean Age/as sponges (A. clathrodes, A. conifera. A dispar. A. longisstma) have been investigated for the alkaloid composition Along with a series of known bromopyrrole alkaloids, two related novel compounds of this class, dispacamides C (7) and D (8), were found and their structures determined with spectroscopic methods All the isolated Agelas. bromopyrrole alkaloids have been evaluated for the antihistaminic activity on the guinea pig ileum.
Antihistaminic activity of the alkaloids isolated from Caribbean Agelas sponges / F., Cafieri; Fattorusso, Ernesto; T., Vallefuoco; TAGLIALATELA SCAFATI, Orazio; Carnuccio, Rosa. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - STAMPA. - 7:(1997), pp. 2283-2288. [10.1016/S0960-894X(97)00415-0]
Antihistaminic activity of the alkaloids isolated from Caribbean Agelas sponges.
FATTORUSSO, ERNESTO;TAGLIALATELA SCAFATI, ORAZIO;CARNUCCIO, ROSA
1997
Abstract
Four Caribbean Age/as sponges (A. clathrodes, A. conifera. A dispar. A. longisstma) have been investigated for the alkaloid composition Along with a series of known bromopyrrole alkaloids, two related novel compounds of this class, dispacamides C (7) and D (8), were found and their structures determined with spectroscopic methods All the isolated Agelas. bromopyrrole alkaloids have been evaluated for the antihistaminic activity on the guinea pig ileum.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.