Simplakidine A, a unique 4-alkyl-substituted pyridiunium alkaloid, has been isolated from the Caribbean sponge Plakortis simplex. The stereostructure of simplakidine A has been determined using MS and NMR data, molecular mechanics, and an extension of the J-based configuration analysis. Data about the growth-inhibition activity of simplakidine A are reported.
Simplakidine A, a Unique Pyridinium Alkaloid From the Caribbean Sponge Plakortis simplex / C., Campagnuolo; Fattorusso, Caterina; Fattorusso, Ernesto; Ianaro, Angela; B., Pisano; TAGLIALATELA SCAFATI, Orazio. - In: ORGANIC LETTERS. - ISSN 1523-7060. - STAMPA. - 5:(2003), pp. 673-676. [10.1021/ol027437r]
Simplakidine A, a Unique Pyridinium Alkaloid From the Caribbean Sponge Plakortis simplex.
FATTORUSSO, CATERINA;FATTORUSSO, ERNESTO;IANARO, ANGELA;TAGLIALATELA SCAFATI, ORAZIO
2003
Abstract
Simplakidine A, a unique 4-alkyl-substituted pyridiunium alkaloid, has been isolated from the Caribbean sponge Plakortis simplex. The stereostructure of simplakidine A has been determined using MS and NMR data, molecular mechanics, and an extension of the J-based configuration analysis. Data about the growth-inhibition activity of simplakidine A are reported.| File | Dimensione | Formato | |
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