Haemostatic disorders in dogs naturally infected by Leishmania infantum

Haemostatic abnormalities such as epistaxis, haematuria and haemorrhagic diarrhoea, have been reported in canine Leishmaniasis (CanL). The object of this study was to evaluate platelet function and secondary haemostasis in dogs naturally infected by L eishmania infantum with different grades of clinical involvement, in order to improve knowledge of the haemostatic disorders found for this protozoan disease. this study demonstrates that in natural CanL primary and secondary haemostatic alterations are related to the severity of clinical symptoms. Collagen agonist could be used as a non-invasive first choice marker for the evaluation of platelet aggregation in a L eishmania infection.