A short and efficient enantioselective synthesis of (R)-3-hydroxydodecanoic acid is described, involving a Sharpless asymmetric dihydroxylation to produce the required (R)-stereochemistry.
Studies toward Lipid A: synthetic strategy for enantioselective preparation of 3-hydroxy fatty acids / Guaragna, Annalisa; DE NISCO, Mauro; Pedatella, Silvana; Palumbo, Giovanni. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - STAMPA. - 17:20(2006), pp. 2839-2841. [10.1016/j.tetasy.2006.10.023]
Studies toward Lipid A: synthetic strategy for enantioselective preparation of 3-hydroxy fatty acids
GUARAGNA, ANNALISA;DE NISCO, MAURO;PEDATELLA, SILVANA;PALUMBO, GIOVANNI
2006
Abstract
A short and efficient enantioselective synthesis of (R)-3-hydroxydodecanoic acid is described, involving a Sharpless asymmetric dihydroxylation to produce the required (R)-stereochemistry.File in questo prodotto:
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