By studying the effect of leucine competitors we found that activation of the specific leucine-transport system underlies the enhancement of leucine uptake in mouse 3T3 fibroblast cells induced by sublethal doses of Amphotericin B (synergic effect). The relation of the antibiotic activity and the alteration of the membrane cholesterol interaction with lipids is discussed.
Influence of amphotericin B on leucine uptake in 3T3 cells / Foresti, Magda; Amati, Paolo. - In: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. - ISSN 0005-2736. - STAMPA. - 732:1(1983), pp. 251-255.
Influence of amphotericin B on leucine uptake in 3T3 cells
FORESTI, MAGDA;AMATI, PAOLO
1983
Abstract
By studying the effect of leucine competitors we found that activation of the specific leucine-transport system underlies the enhancement of leucine uptake in mouse 3T3 fibroblast cells induced by sublethal doses of Amphotericin B (synergic effect). The relation of the antibiotic activity and the alteration of the membrane cholesterol interaction with lipids is discussed.File in questo prodotto:
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