In this paper, we have reported a concise synthesis of all four stereoisomers of beta-methoxytyrosine. The absolute configuration of the above residue in callipeltin A was assigned for the first time. In addition, our method turns out to be a useful tool for the stereochemical characterization of beta-methoxy-beta-aryl amino acids, often found as components of bioactive natural peptides.
Concise Synthesis of All Stereoisomers of b-Methoxytyrosine and Determination of the Absolute Configuration of the Residue in Callipeltin A / Zampella, Angela; D'Orsi, Rosa; Sepe, Valentina; Casapullo, Agostino; Monti, Maria Chiara; D'Auria, MARIA VALERIA. - In: ORGANIC LETTERS. - ISSN 1523-7060. - STAMPA. - 7:16(2005), pp. 3585-3588. [10.1021/ol0513600]
Concise Synthesis of All Stereoisomers of b-Methoxytyrosine and Determination of the Absolute Configuration of the Residue in Callipeltin A
ZAMPELLA, ANGELA;SEPE, VALENTINA;Monti Maria Chiara;D'AURIA, MARIA VALERIA
2005
Abstract
In this paper, we have reported a concise synthesis of all four stereoisomers of beta-methoxytyrosine. The absolute configuration of the above residue in callipeltin A was assigned for the first time. In addition, our method turns out to be a useful tool for the stereochemical characterization of beta-methoxy-beta-aryl amino acids, often found as components of bioactive natural peptides.| File | Dimensione | Formato | |
|---|---|---|---|
|
OL5 beta metossi tirosina.pdf
non disponibili
Tipologia:
Abstract
Licenza:
Accesso privato/ristretto
Dimensione
89.52 kB
Formato
Adobe PDF
|
89.52 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
