Efficacia e tollerabilità di una crema idratante ed antiossidante in pazienti con cute sensibile

Background: skin reactivity towards chemical or physical irritant substances is variable and subjective. The aim of the present study is to evaluate, by means of validated devices and allergologic investigations, modifications induced by a moisturizing cream containing anti-oxidant chemicals when applied to sensitive skin. Materials and methods: 16 female patients with sensitive skin, aged between 15 and 60 years (medium age: 32), were enrolled. The product, containing green tea's polyphenols, soy isoflavones, vitamins E and C, was applied twice daily for a period of 7 days. Evaluation of cutaneous sensitivity was carried out by lactic acid test (stinging test), transepidermal water loss (TEWL) measurement, use test and patch test. Results: 81.2% of the patients had a positive reaction to the lactic acid test: 46.1% of them reported moderate to intense stinging. A significant decrease of TEWL values in treated areas was demonstrated. Both the use test and patch test with the product as is were negative in all the patients. Conclusions: the test product demonstrated moisturizing properties, positive effects on the cutaneous barrier and good acceptability. The data obtained suggest that it could be recommended in treating patients with sensitive skin.