A group of 20 patients affected with thyroid carcinoma, all from Southern Italy, was typed for HLA-A, -B, -C and -DR antigens. Sixteen of them (80%) typed for DR1, while in the control group (120 unrelated healthy individuals from the same region) only 22 (18.3%) shared the same antigen (chi 2 = 32.96). The data indicate a highly significant association between the HLA-DR1 gene and the thyroid carcinoma.
Strong association between an HLA-DR antigen and thyroid carcinoma / Panza, N.; DEL VECCHIO, Luigi; Maio, M.; De Felice, M.; Lombardi, Gaetano; Minozzi, Marco; Zappacosta, Serafino. - In: TISSUE ANTIGENS. - ISSN 0001-2815. - STAMPA. - 20:2(1982), pp. 155-158.
Strong association between an HLA-DR antigen and thyroid carcinoma.
DEL VECCHIO, LUIGI;De Felice M.;LOMBARDI, GAETANO;MINOZZI, MARCO;ZAPPACOSTA, SERAFINO
1982
Abstract
A group of 20 patients affected with thyroid carcinoma, all from Southern Italy, was typed for HLA-A, -B, -C and -DR antigens. Sixteen of them (80%) typed for DR1, while in the control group (120 unrelated healthy individuals from the same region) only 22 (18.3%) shared the same antigen (chi 2 = 32.96). The data indicate a highly significant association between the HLA-DR1 gene and the thyroid carcinoma.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
