A new type of cytotoxic poly-tetrahydrofuran compound, embodying a novel tricyclic spiroketal moiety, has been obtained through an unprecedented PCC-mediated stereoselective oxidative spiroketalization process.
Discovery of a novel one-step RuO4-catalysed tandem oxidative polycyclization/ double spiroketalization process. Access to a new type of polyether bis-spiroketal compound displaying antitumour activity / Piccialli, Vincenzo; Zaccaria, Sabrina; Borbone, Nicola; Oliviero, Giorgia; D'Errico, Stefano; Hemminki, A.; Cerullo, V.; Romano, V.; Tuzi, Angela; Centore, Roberto. - In: TETRAHEDRON. - ISSN 0040-4020. - STAMPA. - 66:(2010), pp. 9370-9378. [10.1016/j.tet.2010.10.004]
Discovery of a novel one-step RuO4-catalysed tandem oxidative polycyclization/ double spiroketalization process. Access to a new type of polyether bis-spiroketal compound displaying antitumour activity
PICCIALLI, VINCENZO;ZACCARIA, SABRINA;BORBONE, NICOLA;OLIVIERO, GIORGIA;D'ERRICO, STEFANO;CERULLO V.;TUZI, ANGELA;CENTORE, ROBERTO
2010
Abstract
A new type of cytotoxic poly-tetrahydrofuran compound, embodying a novel tricyclic spiroketal moiety, has been obtained through an unprecedented PCC-mediated stereoselective oxidative spiroketalization process.| File | Dimensione | Formato | |
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