Benign adult familial myoclonic epilepsy (BAFME) has been mapped to chromosome 8q24; however, genetic heterogeneity has been recently suggested. The authors report a clinical and electrophysiologic study of two Italian BAFME families showing linkage to chromosome 2p11.1-q12.2. Their report supports the evidence of non-Japanese families with BAFME and suggests a possible allelism with the recently described autosomal dominant cortical myoclonus and epilepsy syndrome.
Benign adult familial myoclonic epilepsy: genetic heterogeneity and allelism with ADCME / de Falco, Fa; Striano, Pasquale; de Falco, A; Striano, Salvatore; Santangelo, R; Perretti, A; Balbi, P; Cecconi, M; Zara, F.. - In: NEUROLOGY. - ISSN 0028-3878. - ELETTRONICO. - 22:60(2003), pp. 1381-1385.
Benign adult familial myoclonic epilepsy: genetic heterogeneity and allelism with ADCME.
STRIANO, PASQUALE;STRIANO, SALVATORE;
2003
Abstract
Benign adult familial myoclonic epilepsy (BAFME) has been mapped to chromosome 8q24; however, genetic heterogeneity has been recently suggested. The authors report a clinical and electrophysiologic study of two Italian BAFME families showing linkage to chromosome 2p11.1-q12.2. Their report supports the evidence of non-Japanese families with BAFME and suggests a possible allelism with the recently described autosomal dominant cortical myoclonus and epilepsy syndrome.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
